PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4I8L	Bovine trypsin at 0.87 resolution 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Dauter, Z, Liebschner, D, Dauter, M, Brzuszkiewicz, A. 登録日 2012-12-03 公開日 2012-12-19 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (0.87 Å) 主引用文献 On the reproducibility of protein crystal structures: five atomic resolution structures of trypsin. Acta Crystallogr.,Sect.D, 69, 2013
4HTR	N149W variant of SiRHP bound to sulfite 分子名称: IRON/SULFUR CLUSTER, SIROHEME, SODIUM ION, ... 著者 Smith, K.W, Stroupe, M.E. 登録日 2012-11-01 公開日 2013-01-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Mutational analysis of sulfite reductase hemoprotein reveals the mechanism for coordinated electron and proton transfer. Biochemistry, 51, 2012
4HU9	E. coli thioredoxin variant with (4S)-FluoroPro76 as single proline residue 分子名称: COPPER (II) ION, Thioredoxin-1 著者 Scharer, M.A, Rubini, M, Capitani, G, Glockshuber, R. 登録日 2012-11-02 公開日 2013-05-29 最終更新日 2017-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 (4R)- and (4S)-Fluoroproline in the Conserved cis-Prolyl Peptide Bond of the Thioredoxin Fold: Tertiary Structure Context Dictates Ring Puckering. Chembiochem, 14, 2013
4HWG	Structure of UDP-N-acetylglucosamine 2-epimerase from Rickettsia bellii 分子名称: PHOSPHATE ION, UDP-N-acetylglucosamine 2-epimerase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-11-07 公開日 2012-11-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of UDP-N-acetylglucosamine 2-epimerase from Rickettsia bellii TO BE PUBLISHED
4HWP	Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor 分子名称: N-{[3-(4-amino-2-methylquinazolin-7-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, ZINC ION 著者 Hilgers, M.T. 登録日 2012-11-08 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.807 Å) 主引用文献 Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J.Med.Chem., 56, 2013
3DRI	Crystal structure of Lactococcal OppA co-crystallized with an octamer peptide in an open conformation 分子名称: Oligopeptide-binding protein oppA, peptide AASASA 著者 Berntsson, R.P.-A, Doeven, M.K, Duurkens, R.H, Sengupta, D, Marrink, S.-J, Thunnissen, A.-M, Poolman, B, Slotboom, D.-J. 登録日 2008-07-11 公開日 2009-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structural basis for peptide selection by the transport receptor OppA Embo J., 28, 2009
4HW5	Crystal Structure of the Human C3a anaphylatoxin 分子名称: Complement C3, SULFATE ION 著者 Bajic, G, Yatime, L, Andersen, G.R. 登録日 2012-11-07 公開日 2012-12-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg. Protein Sci., 22, 2013
4HWT	Crystal structure of human Threonyl-tRNA synthetase bound to a novel inhibitor 分子名称: N-{[3-(2H-indazol-5-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, cytoplasmic, ... 著者 Hilgers, M.T. 登録日 2012-11-08 公開日 2013-09-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J.Med.Chem., 56, 2013
4HXK	Brd4 Bromodomain 1 complex with 6,7-DIHYDROTHIENO[3,2-C]PYRIDIN-5(4H)-YL(1H-IMIDAZOL-1-YL)METHANONE inhibitor 分子名称: 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl(1H-imidazol-1-yl)methanone, Bromodomain-containing protein 4 著者 Chen, T.T, Cao, D.Y, Chen, W.Y, Xiong, B, Shen, J.K, Xu, Y.C. 登録日 2012-11-12 公開日 2013-04-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain. J.Med.Chem., 56, 2013
4HXR	Brd4 Bromodomain 1 complex with N-[3-(2-OXO-2,3-DIHYDRO-1,3-THIAZOL-4-YL)PHENYL]THIOPHENE-2-SULFONAMIDE inhibitor 分子名称: Bromodomain-containing protein 4, N-[3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)phenyl]thiophene-2-sulfonamide 著者 Chen, T.T, Cao, D.Y, Chen, W.Y, Xiong, B, Shen, J.K, Xu, Y.C. 登録日 2012-11-12 公開日 2013-04-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain. J.Med.Chem., 56, 2013
3DP1	Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3n 分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, BENZAMIDINE, CHLORIDE ION, ... 著者 Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H. 登録日 2008-07-07 公開日 2009-05-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination. J.Med.Chem., 52, 2009
3DSZ	Engineered human lipocalin 2 in complex with Y-DTPA 分子名称: N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, YTTRIUM (III) ION, engineered human lipocalin 2 著者 Eichinger, A, Skerra, A. 登録日 2008-07-14 公開日 2009-05-19 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 High-affinity recognition of lanthanide(III) chelate complexes by a reprogrammed human lipocalin 2 J.Am.Chem.Soc., 131, 2009
4HZ3	MthK pore crystallized in presence of TBSb 分子名称: Calcium-gated potassium channel mthK, HEXANE-1,6-DIOL, POTASSIUM ION 著者 Posson, D.J, McCoy, J.G, Nimigean, C.M. 登録日 2012-11-14 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The voltage-dependent gate in MthK potassium channels is located at the selectivity filter. Nat.Struct.Mol.Biol., 20, 2013
3F8B	Crystal structure of the multidrug binding transcriptional regulator LmrR in drug free state 分子名称: Transcriptional regulator, PadR-like family 著者 Madoori, P.K, Agustiandari, H, Driessen, A.J.M, Thunnissen, A.-M.W.H. 登録日 2008-11-12 公開日 2008-12-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition. Embo J., 28, 2009
4I1T	Crystal structure of the cap-snatching endonuclease from Pichinde virus 分子名称: RNA-directed RNA polymerase L 著者 Bussetta, C, Choi, K.H. 登録日 2012-11-21 公開日 2014-02-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the cap-snatching endonuclease from Pichinde virus, a new world arenavirus To be Published
4I3E	Crystal structure of Staphylococcal IMPase - I complexed with products. 分子名称: GLYCEROL, Inositol monophosphatase family protein, MAGNESIUM ION, ... 著者 Bhattacharyya, S, Dutta, A, Dutta, D, Das, A.K. 登録日 2012-11-26 公開日 2013-12-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of Staphylococcal IMPase - I complexed with products. To be Published
4I1Y	The structure of Cysteine synthase from Mycobacterium ulcerans Agy99 分子名称: CHLORIDE ION, Cysteine synthase, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-11-21 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4I3Y	Crystal structure of Staphylococcal inositol monophosphatase-1: 100 mM LiCl soaked inhibitory complex 分子名称: GLYCEROL, Inositol monophosphatase family protein, MAGNESIUM ION, ... 著者 Dutta, A, Bhattacharyya, S, Dutta, D, Das, A.K. 登録日 2012-11-26 公開日 2013-11-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural elucidation of the binding site and mode of inhibition of Li(+) and Mg(2+) in inositol monophosphatase. Febs J., 281, 2014
3FCA	Genetic Incorporation of a Metal-ion Chelating Amino Acid into proteins as biophysical probe 分子名称: Cysteine synthase, ZINC ION 著者 Wang, F, Lee, H, Spraggon, G, Schultz, P.G. 登録日 2008-11-21 公開日 2009-02-17 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.149 Å) 主引用文献 Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe. J.Am.Chem.Soc., 131, 2009
4I6U	Crystal Structure of a Y37F mutant of the Restriction-Modification Controller Protein C.Esp1396I 分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Martin, R.N.A, McGeehan, J.E, Kneale, G.G. 登録日 2012-11-30 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I. Plos One, 9, 2014
4I75	Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with the NiTris metalorganic complex 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Inosine-adenosine-guanosine-nucleoside hydrolase, ... 著者 Giannese, F, Degano, M. 登録日 2012-11-30 公開日 2013-08-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor Acta Crystallogr.,Sect.D, 69, 2013
4HSC	Crystal structure of a cholesterol dependent cytolysin 分子名称: Streptolysin O 著者 Feil, S.C, Parker, M.W. 登録日 2012-10-29 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration. J.Mol.Biol., 426, 2014
4IA0	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors 分子名称: 5-bromo-2-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-6-octylpyrimidin-4(3H)-one, MAGNESIUM ION, ZINC ION, ... 著者 Ren, J, Chen, T, Xu, Y. 登録日 2012-12-05 公開日 2014-01-01 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5. Bioorg.Med.Chem.Lett., 23, 2013
4HTT	Crystal Structure of Twin Arginine Translocase Receptor- TatC in DDM 分子名称: Sec-independent protein translocase protein TatC, Lysozyme 著者 Ramasamy, S, Suloway, C.J.M, Clemons Jr, W.M. 登録日 2012-11-01 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (6.8 Å) 主引用文献 The Glove-like Structure of the Conserved Membrane Protein TatC Provides Insight into Signal Sequence Recognition in Twin-Arginine Translocation. Structure, 21, 2013
4HWJ	Crystal Structure of the Human C3a desArg anaphylatoxin 分子名称: Complement C3, SULFATE ION 著者 Bajic, G, Yatime, L, Andersen, G.R. 登録日 2012-11-08 公開日 2012-12-12 最終更新日 2018-03-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg. Protein Sci., 22, 2013

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