PDB: 658 件ウェブページステータス検索Chemie searchBIRD

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6CT4	TFE-induced NMR structure of an antimicrobial peptide (EcDBS1R5) derived from a mercury transporter protein (MerP - Escherichia coli) 分子名称: EcDBS1R5 著者 Cardoso, M.H, Chan, L.Y, Candido, E.S, Craik, D.J, Franco, O.L. 登録日 2018-03-22 公開日 2018-11-14 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 A Computationally Designed Peptide Derived from Escherichia coli as a Potential Drug Template for Antibacterial and Antibiofilm Therapies. ACS Infect Dis, 4, 2018
4A82	Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966. 分子名称: CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR 著者 Rosenberg, M.F, ORyan, L.P, Hughes, G, Zhao, Z, Aleksandrov, L.A, Riordan, J.R, Ford, R.C. 登録日 2011-11-18 公開日 2012-01-11 最終更新日 2024-05-08 実験手法 ELECTRON CRYSTALLOGRAPHY (9 Å) 主引用文献 The Cystic Fibrosis Transmembrane Conductance Regulator (Cftr):3D Structure and Localisation of a Channel Gate. J.Biol.Chem., 286, 2011
7KGE	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-II 分子名称: Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE 著者 Morgan, C.E, Yu, E.W. 登録日 2020-10-16 公開日 2021-03-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGI	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-ET-III 分子名称: ETHIDIUM, Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE 著者 Morgan, C.E, Yu, E.W. 登録日 2020-10-16 公開日 2021-03-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGF	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-III 分子名称: Efflux pump membrane transporter 著者 Morgan, C.E, Yu, E.W. 登録日 2020-10-16 公開日 2021-03-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGH	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-ET-II 分子名称: ETHIDIUM, Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE 著者 Morgan, C.E, Yu, E.W. 登録日 2020-10-16 公開日 2021-03-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.79 Å) 主引用文献 Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGD	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-I 分子名称: Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE 著者 Morgan, C.E, Yu, E.W. 登録日 2020-10-16 公開日 2021-03-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGG	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-ET-I 分子名称: ETHIDIUM, Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE 著者 Morgan, C.E, Yu, E.W. 登録日 2020-10-16 公開日 2021-03-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7PHP	Structure of Multidrug and Toxin Compound Extrusion (MATE) transporter NorM by NabFab-fiducial assisted cryo-EM 分子名称: Anti-Fab nanobody, Multidrug resistance protein NorM, NabFab HC, ... 著者 Bloch, J.S, Mukherjee, S, Kowal, J, Niederer, M, Pardon, E, Steyaert, J, Kossiakoff, A.A, Locher, K.P. 登録日 2021-08-18 公開日 2021-09-01 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins. Proc.Natl.Acad.Sci.USA, 118, 2021
4ZIT	Crystal structure of AcrB in P21 space group 分子名称: DODECYL-BETA-D-MALTOSIDE, Multidrug efflux pump subunit AcrB, NICKEL (II) ION 著者 Ababou, A, Koronakis, V. 登録日 2015-04-28 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.296 Å) 主引用文献 Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZIW	Crystal structure of AcrB deletion mutant in P21 space group 分子名称: DODECYL-BETA-D-MALTOSIDE, Multidrug efflux pump subunit AcrB, NICKEL (II) ION 著者 Ababou, A, Koronakis, V. 登録日 2015-04-28 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.399 Å) 主引用文献 Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZIV	Crystal structure of AcrB triple mutant in P21 space group 分子名称: DODECYL-BETA-D-MALTOSIDE, Multidrug efflux pump subunit AcrB, NICKEL (II) ION 著者 Ababou, A, Koronakis, V. 登録日 2015-04-28 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.16 Å) 主引用文献 Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
7B8S	Fusidic acid bound structure of bacterial efflux pump. 分子名称: DARPin, FUSIDIC ACID, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB 著者 Wilhelm, J, Sjuts, H, Pos, K.M. 登録日 2020-12-13 公開日 2021-10-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms. Nat Commun, 12, 2021
7B8T	Levofloxacin bound structure of bacterial efflux pump. 分子名称: (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, DARPin, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB 著者 Wilhelm, J, Sjuts, H, Pos, K.M. 登録日 2020-12-13 公開日 2021-10-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms. Nat Commun, 12, 2021
7B8R	Doxycycline bound structure of bacterial efflux pump. 分子名称: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, DARPin, DI(HYDROXYETHYL)ETHER, ... 著者 Wilhelm, J, Sjuts, H, Pos, K.M. 登録日 2020-12-13 公開日 2021-10-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms. Nat Commun, 12, 2021
2GHI	Crystal Structure of Plasmodium yoelii Multidrug Resistance Protein 2 分子名称: SULFATE ION, transport protein 著者 Dong, A, Gao, M, Choe, J, Zhao, Y, Lew, J, Wasney, G, Alam, Z, Melone, M, Kozieradzki, I, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC) 登録日 2006-03-27 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
5IHJ	Fusion of Maltose-binding Protein and PilA from Acinetobacter baumannii BIDMC57 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, GLYCEROL, ... 著者 Piepenbrink, K.H, Sundberg, E.J. 登録日 2016-02-29 公開日 2016-09-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Diversity in the Type IV Pili of Multidrug-resistant Acinetobacter. J.Biol.Chem., 291, 2016
7OCY	Enterococcus faecalis EfrCD in complex with a nanobody 分子名称: ABC transporter ATP-binding protein, Nanobody 著者 Ehrenbolger, K, Hutter, C.A.J, Meier, G, Seeger, M.A, Barandun, J. 登録日 2021-04-28 公開日 2022-05-18 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.25 Å) 主引用文献 Deep mutational scan of a drug efflux pump reveals its structure-function landscape. Nat.Chem.Biol., 19, 2023
4Q4J	Structure of crosslinked TM287/288_S498C_S520C mutant 分子名称: ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288 著者 Hohl, M, Schoeppe, J, Gruetter, M.G, Seeger, M.A. 登録日 2014-04-14 公開日 2014-07-16 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proc.Natl.Acad.Sci.USA, 111, 2014
4ZJO	Crystal structure of AcrB triple mutant in complex with antibiotic in P21 space group 分子名称: DODECYL-BETA-D-MALTOSIDE, ERYTHROMYCIN A, Multidrug efflux pump subunit AcrB, ... 著者 Ababou, A, Koronakis, V. 登録日 2015-04-29 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZJQ	Crystal structure of AcrB deletion mutant in complex with antibiotic in P21 space group 分子名称: DODECYL-BETA-D-MALTOSIDE, ERYTHROMYCIN A, Multidrug efflux pump subunit AcrB, ... 著者 Ababou, A, Koronakis, V. 登録日 2015-04-29 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.592 Å) 主引用文献 Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZJL	Crystal structure of AcrB in complex with antibiotic in P21 space group 分子名称: DODECYL-BETA-D-MALTOSIDE, ERYTHROMYCIN A, Multidrug efflux pump subunit AcrB, ... 著者 Ababou, A, Koronakis, V. 登録日 2015-04-29 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.47 Å) 主引用文献 Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4Q4H	TM287/288 in its apo state 分子名称: ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288 著者 Hohl, M, Gruetter, M.G, Seeger, M.A. 登録日 2014-04-14 公開日 2014-07-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.527 Å) 主引用文献 Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proc.Natl.Acad.Sci.USA, 111, 2014
4DK1	Crystal Structure of MacA-MexA chimeric protein, containing the Pseudomonas aeruginosa MexA alpha-hairpin domain. 分子名称: Putative MacA, Multidrug resistance protein mexA 著者 Xu, Y, Ha, N.C. 登録日 2012-02-03 公開日 2012-03-07 最終更新日 2017-08-23 実験手法 X-RAY DIFFRACTION (3.499 Å) 主引用文献 Assembly and channel opening of outer membrane protein in tripartite drug efflux pumps of Gram-negative bacteria. J.Biol.Chem., 287, 2012
5CFV	Fusion of Maltose-binding Protein and PilA from Acinetobacter nosocomialis M2 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, MAGNESIUM ION, ... 著者 Piepenbrink, K.H, Sundberg, E.J. 登録日 2015-07-08 公開日 2016-07-13 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Diversity in the Type IV Pili of Multidrug-resistant Acinetobacter. J.Biol.Chem., 291, 2016

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