6ZH4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zh4 by Molmil](/molmil-images/mine/6zh4) | Cryo-EM structure of DNA-PKcs (State 3) | 分子名称: | DNA-dependent protein kinase catalytic subunit,DNA-PKcs | 著者 | Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L. | 登録日 | 2020-06-20 | 公開日 | 2020-10-21 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28, 2021
|
|
6ZH8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zh8 by Molmil](/molmil-images/mine/6zh8) | Cryo-EM structure of DNA-PKcs:DNA | 分子名称: | DNA (5'-D(P*AP*CP*TP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*AP*GP*TP*TP*TP*TP*TP*AP*GP*TP*T)-3'), DNA-dependent protein kinase catalytic subunit,DNA-PKcs | 著者 | Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L. | 登録日 | 2020-06-21 | 公開日 | 2020-10-21 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | 主引用文献 | Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28, 2021
|
|
6UR2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ur2 by Molmil](/molmil-images/mine/6ur2) | |
6UR4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ur4 by Molmil](/molmil-images/mine/6ur4) | |
4YFU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yfu by Molmil](/molmil-images/mine/4yfu) | |
6BTF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6btf by Molmil](/molmil-images/mine/6btf) | DNA Polymerase Beta I260Q Ternary Complex | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA Downstream Strand, DNA Primer Strand, ... | 著者 | Eckenroth, B.E, Doublie, S. | 登録日 | 2017-12-06 | 公開日 | 2018-09-26 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity. Nucleic Acids Res., 46, 2018
|
|
6BTE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bte by Molmil](/molmil-images/mine/6bte) | DNA Polymerase Beta I260Q Binary Complex | 分子名称: | CHLORIDE ION, DNA Downstream Strand, DNA Primer Strand, ... | 著者 | Eckenroth, B.E, Doublie, S. | 登録日 | 2017-12-06 | 公開日 | 2018-09-26 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity. Nucleic Acids Res., 46, 2018
|
|
6UHN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uhn by Molmil](/molmil-images/mine/6uhn) | Crystal Structure of C148 mGFP-cDNA-1 | 分子名称: | C148 mGFP-cDNA-1, UNKNOWN LIGAND | 著者 | Winegar, P.W, Hayes, O.G, McMillan, J.R, Figg, C.A, Focia, P.J, Mirkin, C.A. | 登録日 | 2019-09-27 | 公開日 | 2020-03-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | DNA-Directed Protein Packing within Single Crystals. Chem, 6, 2020
|
|
6UHQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uhq by Molmil](/molmil-images/mine/6uhq) | Crystal Structure of C148 mGFP-cDNA-3 | 分子名称: | C148 mGFP-cDNA-3, UNKNOWN LIGAND | 著者 | Winegar, P.W, Hayes, O.G, McMillan, J.R, Figg, C.A, Focia, P.J, Mirkin, C.A. | 登録日 | 2019-09-27 | 公開日 | 2020-03-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | DNA-Directed Protein Packing within Single Crystals. Chem, 6, 2020
|
|
6UHR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uhr by Molmil](/molmil-images/mine/6uhr) | Crystal Structure of C148 mGFP-scDNA-2 | 分子名称: | C148 mGFP-scDNA-2 | 著者 | Winegar, P.W, Hayes, O.G, McMillan, J.R, Figg, C.A, Focia, P.J, Mirkin, C.A. | 登録日 | 2019-09-27 | 公開日 | 2020-03-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | DNA-Directed Protein Packing within Single Crystals. Chem, 6, 2020
|
|
6UHP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uhp by Molmil](/molmil-images/mine/6uhp) | Crystal Structure of C148 mGFP-ncDNA-1 | 分子名称: | C148 mGFP-ncDNA-1 | 著者 | Winegar, P.W, Hayes, O.G, McMillan, J.R, Figg, C.A, Focia, P.J, Mirkin, C.A. | 登録日 | 2019-09-27 | 公開日 | 2020-03-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | DNA-Directed Protein Packing within Single Crystals. Chem, 6, 2020
|
|
6UHL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uhl by Molmil](/molmil-images/mine/6uhl) | Crystal Structure of C148 mGFP-scDNA-1 | 分子名称: | C148 mGFP-scDNA-1, UNKNOWN LIGAND | 著者 | Winegar, P.W, Hayes, O.G, McMillan, J.R, Figg, C.A, Focia, P.J, Mirkin, C.A. | 登録日 | 2019-09-27 | 公開日 | 2020-03-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | DNA-Directed Protein Packing within Single Crystals. Chem, 6, 2020
|
|
7K97
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k97 by Molmil](/molmil-images/mine/7k97) | |
5Y3R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y3r by Molmil](/molmil-images/mine/5y3r) | Cryo-EM structure of Human DNA-PK Holoenzyme | 分子名称: | DNA (34-MER), DNA (36-MER), DNA-dependent protein kinase catalytic subunit, ... | 著者 | Yin, X, Liu, M, Tian, Y, Wang, J, Xu, Y. | 登録日 | 2017-07-29 | 公開日 | 2017-09-06 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Cryo-EM structure of human DNA-PK holoenzyme Cell Res., 27, 2017
|
|
5A9J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5a9j by Molmil](/molmil-images/mine/5a9j) | Crystal structure of the Helicase domain of human DNA polymerase theta, apo-form | 分子名称: | DNA POLYMERASE THETA | 著者 | Newman, J.A, Cooper, C.D.O, Aitkenhead, H, Pinkas, D.M, Kupinska, K, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2015-07-21 | 公開日 | 2015-12-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | 主引用文献 | Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. Structure, 23, 2015
|
|
6NUA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nua by Molmil](/molmil-images/mine/6nua) | |
6UHO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uho by Molmil](/molmil-images/mine/6uho) | Crystal Structure of C148 mGFP-cDNA-2 | 分子名称: | C148 mGFP-cDNA-2, UNKNOWN LIGAND | 著者 | Winegar, P.W, Hayes, O.G, McMillan, J.R, Figg, C.A, Focia, P.J, Mirkin, C.A. | 登録日 | 2019-09-27 | 公開日 | 2020-03-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | DNA-Directed Protein Packing within Single Crystals. Chem, 6, 2020
|
|
7K1K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k1k by Molmil](/molmil-images/mine/7k1k) | CryoEM structure of inactivated-form DNA-PK (Complex IV) | 分子名称: | DNA (5'-D(*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*GP*CP*A)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3'), DNA-dependent protein kinase catalytic subunit, ... | 著者 | Chen, X, Gellert, M, Yang, W. | 登録日 | 2020-09-07 | 公開日 | 2021-01-06 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure of an activated DNA-PK and its implications for NHEJ. Mol.Cell, 81, 2021
|
|
3ISC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3isc by Molmil](/molmil-images/mine/3isc) | Binary complex of human DNA polymerase beta with an abasic site (THF) in the gapped DNA | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*(3DR)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | 著者 | Beard, W.A, Shock, D.D, Batra, V.K, Pedersen, L.C, Wilson, S.H. | 登録日 | 2009-08-25 | 公開日 | 2009-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | DNA polymerase beta substrate specificity: side chain modulation of the "A-rule". J.Biol.Chem., 284, 2009
|
|
3ISD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3isd by Molmil](/molmil-images/mine/3isd) | Ternary complex of human DNA polymerase beta with an abasic site (THF): DAPCPP mismatch | 分子名称: | 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, 5'-D(*CP*CP*GP*AP*CP*(3DR)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', ... | 著者 | Beard, W.A, Shock, D.D, Batra, V.K, Pedersen, L.C, Wilson, S.H. | 登録日 | 2009-08-25 | 公開日 | 2009-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | DNA polymerase beta substrate specificity: side chain modulation of the "A-rule". J.Biol.Chem., 284, 2009
|
|
3ISB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3isb by Molmil](/molmil-images/mine/3isb) | Binary complex of human DNA polymerase beta with a gapped DNA | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | 著者 | Beard, W.A, Shock, D.D, Batra, V.K, Pedersen, L.C, Wilson, S.H. | 登録日 | 2009-08-25 | 公開日 | 2009-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | DNA polymerase beta substrate specificity: side chain modulation of the "A-rule". J.Biol.Chem., 284, 2009
|
|
7K1J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k1j by Molmil](/molmil-images/mine/7k1j) | CryoEM structure of inactivated-form DNA-PK (Complex III) | 分子名称: | DNA (5'-D(*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*GP*CP*A)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3'), DNA-dependent protein kinase catalytic subunit, ... | 著者 | Chen, X, Gellert, M, Yang, W. | 登録日 | 2020-09-07 | 公開日 | 2021-01-06 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of an activated DNA-PK and its implications for NHEJ. Mol.Cell, 81, 2021
|
|
3VDY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vdy by Molmil](/molmil-images/mine/3vdy) | B. subtilis SsbB/ssDNA | 分子名称: | 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', Single-stranded DNA-binding protein ssbB | 著者 | Yadav, T, Carrasco, B, Myers, A.R, George, N.P, Keck, J.L, Alonso, J.C. | 登録日 | 2012-01-06 | 公開日 | 2012-03-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Genetic recombination in Bacillus subtilis: a division of labor between two single-strand DNA-binding proteins. Nucleic Acids Res., 40, 2012
|
|
7K1N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k1n by Molmil](/molmil-images/mine/7k1n) | CryoEM structure of inactivated-form DNA-PK (Complex V) | 分子名称: | DNA (5'-D(P*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*GP*CP*A)-3'), DNA (5'-D(P*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3'), DNA-dependent protein kinase catalytic subunit, ... | 著者 | Chen, X, Gellert, M, Yang, W. | 登録日 | 2020-09-08 | 公開日 | 2021-01-06 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of an activated DNA-PK and its implications for NHEJ. Mol.Cell, 81, 2021
|
|
7OWF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7owf by Molmil](/molmil-images/mine/7owf) | KlenTaq DNA polymerase in a ternary complex with primer/template and the fluorescent nucleotide analog BFdUTP | 分子名称: | DNA polymerase I, thermostable, GLYCEROL, ... | 著者 | Betz, K, Srivatsan, S.G. | 登録日 | 2021-06-18 | 公開日 | 2022-06-29 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Microenvironment-Sensitive Fluorescent Nucleotide Probes from Benzofuran, Benzothiophene, and Selenophene as Substrates for DNA Polymerases. J.Am.Chem.Soc., 144, 2022
|
|