7AUS
 
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7AUO
 | | Yeast Diphosphoinositol Polyphosphate Phosphohydrolase DDP1 in complex with PA-InsP8 | | 分子名称: | Diphosphoinositol polyphosphate phosphohydrolase DDP1, {[(1R,3S,4S,5R,6S)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl]bis[oxy(2-oxoethane-2,1-diyl)]}bis(phosphonic acid) | | 著者 | Marquez-Monino, M.A, Gonzalez, B. | | 登録日 | 2020-11-03 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Multiple substrate recognition by yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase through phosphate clamping.
Sci Adv, 7, 2021
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7AUL
 | | Yeast Diphosphoinositol Polyphosphate Phosphohydrolase DDP1 in complex with 5-InsP7 in presence of Mg | | 分子名称: | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, ACETATE ION, Diphosphoinositol polyphosphate phosphohydrolase DDP1, ... | | 著者 | Marquez-Monino, M.A, Gonzalez, B. | | 登録日 | 2020-11-03 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Multiple substrate recognition by yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase through phosphate clamping.
Sci Adv, 7, 2021
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7AUQ
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7AUI
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7AUR
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7AUK
 | | Yeast Diphosphoinositol Polyphosphate Phosphohydrolase DDP1 in complex with 5-InsP7 | | 分子名称: | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, Diphosphoinositol polyphosphate phosphohydrolase DDP1 | | 著者 | Marquez-Monino, M.A, Gonzalez, B. | | 登録日 | 2020-11-03 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Multiple substrate recognition by yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase through phosphate clamping.
Sci Adv, 7, 2021
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6K4D
 | | Ancestral luciferase AncLamp in complex with ATP and D-luciferin | | 分子名称: | (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid, Ancestral luciferase AncLamp, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] (4S)-2-(6-oxidanyl-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylate | | 著者 | Oba, Y, Konishi, K, Yano, D, Kato, D, Shirai, T. | | 登録日 | 2019-05-23 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Resurrecting the ancient glow of the fireflies.
Sci Adv, 6, 2020
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2NO3
 | | Novel 4-anilinopyrimidines as potent JNK1 Inhibitors | | 分子名称: | 2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE, C-JUN-AMINO-TERMINAL KINASE-INTERACTING protein 1, Mitogen-activated protein kinase 8, ... | | 著者 | Abad-Zapatero, C. | | 登録日 | 2006-10-24 | | 公開日 | 2007-04-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies.
Bioorg.Med.Chem.Lett., 17, 2007
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2H96
 | | Discovery of Potent, Highly Selective, and Orally Bioavailable Pyridine Carboxamide C-jun NH2-terminal Kinase Inhibitors | | 分子名称: | 5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE, C-jun-amino-terminal kinase-interacting protein 1, GLYCEROL, ... | | 著者 | Abad-Zapatero, C. | | 登録日 | 2006-06-09 | | 公開日 | 2006-07-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Discovery of potent, highly selective, and orally bioavailable pyridine carboxamide c-Jun NH2-terminal kinase inhibitors.
J.Med.Chem., 49, 2006
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6K4C
 | | Ancestral luciferase AncLamp in complex with DLSA | | 分子名称: | 5'-O-[N-(DEHYDROLUCIFERYL)-SULFAMOYL] ADENOSINE, Ancestral luciferase AncLamp, MAGNESIUM ION | | 著者 | Oba, Y, Konishi, K, Yano, D, Kato, D, Shirai, T. | | 登録日 | 2019-05-23 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Resurrecting the ancient glow of the fireflies.
Sci Adv, 6, 2020
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2GMX
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2G01
 | | Pyrazoloquinolones as Novel, Selective JNK1 inhibitors | | 分子名称: | 6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE, C-jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 8, ... | | 著者 | Abad-Zapatero, C. | | 登録日 | 2006-02-10 | | 公開日 | 2006-04-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
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3O17
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3NEW
 | | p38-alpha complexed with Compound 10 | | 分子名称: | 4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, Mitogen-activated protein kinase 14 | | 著者 | Goedken, E.R, Comess, K.M, Sun, C, Argiriadi, M, Jia, Y, Quinn, C.M, Banach, D.L, Marcotte, D, Borhani, D. | | 登録日 | 2010-06-09 | | 公開日 | 2010-12-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases.
Acs Chem.Biol., 6, 2011
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3O2M
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6DJY
 | | Fako virus | | 分子名称: | Clamp protein, Major capsid protein, Turret protein | | 著者 | Kaelber, J.T, Jiang, W, Weaver, S.C, Auguste, A.J, Chiu, W. | | 登録日 | 2018-05-27 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | The polymerase organization of Fako virus
To be Published
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8FJL
 | | Golden Shiner Reovirus Core Tropical Vertex | | 分子名称: | Clamp protein VP6, Major inner capsid protein VP3, Microtubule-associated protein VP5, ... | | 著者 | Stevens, A.S, Zhou, Z.H. | | 登録日 | 2022-12-19 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Asymmetric reconstruction of the aquareovirus core at near-atomic resolution and mechanism of transcription initiation.
Protein Cell, 14, 2023
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8FJK
 | | Golden Shiner Reovirus Core Polar Vertex | | 分子名称: | Clamp protein VP6, Major inner capsid protein VP3, Microtubule-associated protein VP5, ... | | 著者 | Stevens, A.S, Zhou, Z.H. | | 登録日 | 2022-12-19 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Asymmetric reconstruction of the aquareovirus core at near-atomic resolution and mechanism of transcription initiation.
Protein Cell, 14, 2023
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6DJK
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6PSN
 | | Anthrax toxin protective antigen channels bound to lethal factor | | 分子名称: | CALCIUM ION, Lethal factor, Protective antigen | | 著者 | Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. | | 登録日 | 2019-07-12 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
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5M1S
 | | Cryo-EM structure of the E. coli replicative DNA polymerase-clamp-exonuclase-theta complex bound to DNA in the editing mode | | 分子名称: | DNA Primer Strand, DNA Template Strand, DNA polymerase III subunit alpha, ... | | 著者 | Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. | | 登録日 | 2016-10-10 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Self-correcting mismatches during high-fidelity DNA replication.
Nat. Struct. Mol. Biol., 24, 2017
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6DJ8
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6WJJ
 | | Anthrax octamer prechannel bound to full-length lethal factor | | 分子名称: | CALCIUM ION, Lethal factor, Protective antigen, ... | | 著者 | Zhou, K, Hardenbrook, N.J, Liu, S, Cui, Y.X, Krantz, B.A, Zhou, Z.H. | | 登録日 | 2020-04-13 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors.
Structure, 28, 2020
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6UZB
 | | Anthrax toxin protective antigen channels bound to edema factor | | 分子名称: | CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen | | 著者 | Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. | | 登録日 | 2019-11-14 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
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