6K0T
 
 | | Crystal Structure of PPARgamma Ligand Binding Domain in complex with dibenzooxepine derivative compound-17 | | 分子名称: | 3-[(1~{E})-1-[8-[(8-chloranyl-2-cyclopropyl-imidazo[1,2-a]pyridin-3-yl)methyl]-3-fluoranyl-6~{H}-benzo[c][1]benzoxepin-11-ylidene]ethyl]-4~{H}-1,2,4-oxadiazol-5-one, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | | 著者 | Suzuki, M, Yamamoto, K, Takahashi, Y, Saito, J. | | 登録日 | 2019-05-07 | | 公開日 | 2019-10-30 | | 最終更新日 | 2019-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Development of a novel class of peroxisome proliferator-activated receptor (PPAR) gamma ligands as an anticancer agent with a unique binding mode based on a non-thiazolidinedione scaffold.
Bioorg.Med.Chem., 27, 2019
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5GVC
 | | Human Topoisomerase IIIb topo domain | | 分子名称: | DNA topoisomerase 3-beta-1, MAGNESIUM ION | | 著者 | Goto-Ito, S, Yamagata, A, Sato, Y, Takahashi, T.S, Fukai, S. | | 登録日 | 2016-09-05 | | 公開日 | 2017-06-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.436 Å) | | 主引用文献 | Structural basis of the interaction between Topoisomerase III beta and the TDRD3 auxiliary factor
Sci Rep, 7, 2017
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6KFY
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6JZV
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1CJ6
 | | T11A MUTANT HUMAN LYSOZYME | | 分子名称: | PROTEIN (LYSOZYME), SODIUM ION | | 著者 | Takano, K, Yamagata, Y, Funahashi, J, Yutani, K. | | 登録日 | 1999-04-22 | | 公開日 | 1999-04-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of intra- and intermolecular hydrogen bonds to the conformational stability of human lysozyme(,).
Biochemistry, 38, 1999
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1CJ8
 | | T40A MUTANT HUMAN LYSOZYME | | 分子名称: | PROTEIN (LYSOZYME), SODIUM ION | | 著者 | Takano, K, Yamagata, Y, Funahashi, J, Yutani, K. | | 登録日 | 1999-04-22 | | 公開日 | 1999-04-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of intra- and intermolecular hydrogen bonds to the conformational stability of human lysozyme(,).
Biochemistry, 38, 1999
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1CJ7
 | | T11V MUTANT HUMAN LYSOZYME | | 分子名称: | PROTEIN (LYSOZYME), SODIUM ION | | 著者 | Takano, K, Yamagata, Y, Funahashi, J, Yutani, K. | | 登録日 | 1999-04-22 | | 公開日 | 1999-04-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of intra- and intermolecular hydrogen bonds to the conformational stability of human lysozyme(,).
Biochemistry, 38, 1999
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1DET
 | | RIBONUCLEASE T1 CARBOXYMETHYLATED AT GLU 58 IN COMPLEX WITH 2'GMP | | 分子名称: | GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1, SODIUM ION | | 著者 | Ishikawa, K, Suzuki, E, Tanokura, M, Takahashi, K. | | 登録日 | 1996-02-20 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of ribonuclease T1 carboxymethylated at Glu58 in complex with 2'-GMP.
Biochemistry, 35, 1996
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3VUP
 | | Beta-1,4-mannanase from the common sea hare Aplysia kurodai | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-1,4-mannanase, SULFATE ION | | 著者 | Mizutani, K, Tsuchiya, S, Toyoda, M, Nanbu, Y, Tominaga, K, Yuasa, K, Takahashi, N, Tsuji, A, Mikami, B. | | 登録日 | 2012-07-04 | | 公開日 | 2012-10-17 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Structure of beta-1,4-mannanase from the common sea hare Aplysia kurodai at 1.05 A resolution.
Acta Crystallogr.,Sect.F, 68, 2012
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3VKP
 | | Assimilatory nitrite reductase (Nii3) - NO2 complex from tobbaco leaf analysed with low X-ray dose | | 分子名称: | CHLORIDE ION, IRON/SULFUR CLUSTER, NITRITE ION, ... | | 著者 | Nakano, S, Takahashi, M, Sakamoto, A, Morikawa, H, Katayanagi, K. | | 登録日 | 2011-11-20 | | 公開日 | 2012-04-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | The reductive reaction mechanism of tobacco nitrite reductase derived from a combination of crystal structures and ultraviolet-visible microspectroscopy
Proteins, 80, 2012
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3VHM
 | | Crystal structure of NPC-biotin-avidin complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[(3aS,4R,6aR)-1-{[(1R)-1-(6-nitro-1,3-benzodioxol-5-yl)ethoxy]carbonyl}-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid, Avidin, ... | | 著者 | Terai, T, Maki, E, Sugiyama, S, Takahashi, Y, Matsumura, H, Mori, Y, Nagano, T. | | 登録日 | 2011-08-29 | | 公開日 | 2011-12-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Rational development of caged-biotin protein-labeling agents and some applications in live cells
Chem.Biol., 18, 2011
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3W54
 | | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with colletochlorin B | | 分子名称: | 3-chloro-5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-4,6-dihydroxy-2-methylbenzaldehyde, Alternative oxidase, mitochondrial, ... | | 著者 | Shiba, T, Kido, Y, Sakamoto, K, Inaoka, D.K, Tsuge, C, Tatsumi, R, Takahashi, G, Balogun, E.O, Nara, T, Aoki, T, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Saimoto, H, Moore, A.L, Harada, S, Kita, K. | | 登録日 | 2013-01-21 | | 公開日 | 2013-03-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the trypanosome cyanide-insensitive alternative oxidase
Proc.Natl.Acad.Sci.USA, 110, 2013
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3WJ2
 | | Crystal structure of ESTFA (FE-lacking apo form) | | 分子名称: | Carboxylesterase | | 著者 | Ohara, K, Unno, H, Oshima, Y, Furukawa, K, Fujino, N, Hirooka, K, Hemmi, H, Takahashi, S, Nishino, T, Kusunoki, M, Nakayama, T. | | 登録日 | 2013-10-03 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Structural insights into the low pH adaptation of a unique carboxylesterase from Ferroplasma: altering the pH optima of two carboxylesterases.
J.Biol.Chem., 289, 2014
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3WJ1
 | | Crystal structure of SSHESTI | | 分子名称: | Carboxylesterase, octyl beta-D-glucopyranoside | | 著者 | Ohara, K, Unno, H, Oshima, Y, Furukawa, K, Fujino, N, Hirooka, K, Hemmi, H, Takahashi, S, Nishino, T, Kusunoki, M, Nakayama, T. | | 登録日 | 2013-10-03 | | 公開日 | 2014-07-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural insights into the low pH adaptation of a unique carboxylesterase from Ferroplasma: altering the pH optima of two carboxylesterases.
J.Biol.Chem., 289, 2014
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3X27
 | | Structure of McbB in complex with tryptophan | | 分子名称: | Cucumopine synthase, TRYPTOPHAN | | 著者 | Mori, T, Sahashi, S, Morita, H, Abe, I. | | 登録日 | 2014-12-10 | | 公開日 | 2015-10-28 | | 最終更新日 | 2015-11-04 | | 実験手法 | X-RAY DIFFRACTION (2.481 Å) | | 主引用文献 | Structural Basis for beta-Carboline Alkaloid Production by the Microbial Homodimeric Enzyme McbB
Chem.Biol., 22, 2015
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3WQH
 | | Crystal Structure of human DPP-IV in complex with Anagliptin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide | | 著者 | Watanabe, Y.S, Okada, S, Motoyama, T, Takahashi, R, Adachi, H, Oka, M. | | 登録日 | 2014-01-27 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Anagliptin, a potent dipeptidyl peptidase IV inhibitor: its single-crystal structure and enzyme interactions.
J Enzyme Inhib Med Chem, 30, 2015
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5WRL
 | | Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y628 peptide | | 分子名称: | AP-2 complex subunit mu, Insulin receptor substrate 1 | | 著者 | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | | 登録日 | 2016-12-02 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.095 Å) | | 主引用文献 | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
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5WRK
 | | Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y608 peptide | | 分子名称: | AP-2 complex subunit mu, Insulin receptor substrate 1, NICKEL (II) ION | | 著者 | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | | 登録日 | 2016-12-02 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
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6KBI
 | | Crystal structure of ErbB3 N418Q mutant | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-3 | | 著者 | Kato, K, Yao, M. | | 登録日 | 2019-06-25 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of ErbB3 N418Q mutant
To Be Published
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7VY3
 | | STRUCTURE OF PHOTOSYNTHETIC LH1-RC SUPER-COMPLEX OF RHODOBACTER SPHAEROIDES LACKING PROTEIN-U | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Antenna pigment protein alpha chain, Antenna pigment protein beta chain, ... | | 著者 | Tani, K, Kanno, R, Kawamura, S, Kikuchi, R, Nagashima, K.V.P, Hall, M, Takahashi, A, Yu, L.-J, Kimura, Y, Madigan, M.T, Mizoguchi, A, Humbel, B.M, Wang-Otomo, Z.-Y. | | 登録日 | 2021-11-13 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | Asymmetric structure of the native Rhodobacter sphaeroides dimeric LH1-RC complex.
Nat Commun, 13, 2022
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7VY2
 | | STRUCTURE OF PHOTOSYNTHETIC LH1-RC SUPER-COMPLEX OF RHODOBACTER SPHAEROIDES DIMER | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Antenna pigment protein alpha chain, Antenna pigment protein beta chain, ... | | 著者 | Tani, K, Kanno, R, Kawamura, S, Kikuchi, R, Nagashima, K.V.P, Hall, M, Takahashi, A, Yu, L.-J, Kimura, Y, Madigan, M.T, Mizoguchi, A, Humbel, B.M, Wang-Otomo, Z.-Y. | | 登録日 | 2021-11-13 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Asymmetric structure of the native Rhodobacter sphaeroides dimeric LH1-RC complex.
Nat Commun, 13, 2022
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7VPC
 | | Neryl diphosphate synthase from Solanum lycopersicum | | 分子名称: | 1,2-ETHANEDIOL, D-MALATE, Neryl-diphosphate synthase 1 | | 著者 | Imaizumi, R, Misawa, S, Takeshita, K, Sakai, N, Yamamoto, M, Kataoka, K, Nakayama, T, Takahashi, S, Yamashita, S. | | 登録日 | 2021-10-15 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structure-based engineering of a short-chain cis-prenyltransferase to biosynthesize nonnatural all-cis-polyisoprenoids: molecular mechanisms for primer substrate recognition and ultimate product chain-length determination.
Febs J., 289, 2022
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7VUS
 | | Crystal structure of AlleyCat9 with 5-nitro-benzotriazole | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-nitro-1H-benzotriazole, AlleyCat, ... | | 著者 | Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K. | | 登録日 | 2021-11-04 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | NMR-guided directed evolution.
Nature, 610, 2022
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7VUR
 | | Crystal structure of AlleyCat9 with calcium but no inhibitor | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, AlleyCat, CALCIUM ION | | 著者 | Margheritis, E, Takahashi, K, Korendovych, I.V, Tame, J.R.H. | | 登録日 | 2021-11-04 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | NMR-guided directed evolution.
Nature, 610, 2022
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5XXL
 | | Crystal structure of GH3 beta-glucosidase from Bacteroides thetaiotaomicron | | 分子名称: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Periplasmic beta-glucosidase, ... | | 著者 | Nakajima, M, Ishiguro, R, Tanaka, N, Abe, K, Maeda, T, Miyanaga, A, Takahash, Y, Sugimoto, N, Nakai, H, Taguchi, H. | | 登録日 | 2017-07-04 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Function and structure relationships of a beta-1,2-glucooligosaccharide-degrading beta-glucosidase.
FEBS Lett., 591, 2017
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