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6WFO
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Crystal structure of human Naa50 in complex with AcCoA and an inhibitor (compound 4b) identified using DNA encoded library technology
分子名称: (4S)-1-methyl-N-{(3S,5R)-5-[4-(methylcarbamoyl)-1,3-thiazol-2-yl]-1-[4-(1H-tetrazol-5-yl)benzene-1-carbonyl]pyrrolidin-3-yl}-2,6-dioxohexahydropyrimidine-4-carboxamide, ACETYL COENZYME *A, N-alpha-acetyltransferase 50
著者Greasley, S.E, Feng, J, Deng, Y.-L, Stewart, A.E.
登録日2020-04-03
公開日2020-07-01
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.
Acs Med.Chem.Lett., 11, 2020
2I79
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BU of 2i79 by Molmil
The crystal structure of the acetyltransferase of GNAT family from Streptococcus pneumoniae
分子名称: ACETYL COENZYME *A, Acetyltransferase, GNAT family
著者Zhang, R.G, Zhou, M, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-08-30
公開日2006-10-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of the acetyltransferase of GNAT family from Streptococcus pneumoniae
To be Published
6SK1
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BU of 6sk1 by Molmil
Diaminobutyrate acetyltransferase EctA from Paenibacillus lautus in complex with coenzyme A
分子名称: ACETATE ION, COENZYME A, L-2,4-diaminobutyric acid acetyltransferase
著者Richter, A.A, Kobus, S, Czech, L, Hoeppner, A, Bremer, E, Smits, S.H.J.
登録日2019-08-14
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine.
J.Biol.Chem., 295, 2020
5DED
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BU of 5ded by Molmil
Crystal structure of the small alarmone synthethase 1 from Bacillus subtilis bound to its product pppGpp
分子名称: GTP pyrophosphokinase YjbM, MAGNESIUM ION, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)
著者Steinchen, W, Schuhmacher, J.S, Altegoer, F, Bange, G.
登録日2015-08-25
公開日2015-10-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.942 Å)
主引用文献Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone.
Proc.Natl.Acad.Sci.USA, 112, 2015
8GQD
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BU of 8gqd by Molmil
Complex Structure of Arginine Kinase McsB and McsA from Staphylococcus aureus
分子名称: Protein-arginine kinase, Protein-arginine kinase activator protein, ZINC ION
著者Lu, K, Luo, B, Tao, X, Li, H, Xie, Y, Zhao, Z, Xia, W, Su, Z, Mao, Z.
登録日2022-08-30
公開日2024-03-06
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Complex structure and activation mechanism of arginine kinase McsB by McsA.
Nat.Chem.Biol., 2024
5DGN
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BU of 5dgn by Molmil
Crystal structure of human FPPS in complex with compound 13
分子名称: 8-(naphthalen-1-yl)quinoline-2-carboxylic acid, Farnesyl pyrophosphate synthase
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-08-28
公開日2015-09-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
6SFA
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BU of 6sfa by Molmil
Trypanosoma cruzi farnesyl diphosphate synthase apo structure with Mn ions
分子名称: Farnesyl diphosphate synthase, MANGANESE (II) ION, SULFATE ION
著者Magari, F, Heine, A, Klebe, G.
登録日2019-08-01
公開日2020-08-26
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Trypanosoma cruzi farnesyl diphosphate synthase apo structure with Mn ions
To Be Published
5D6O
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BU of 5d6o by Molmil
Orthorhombic Crystal Structure of an acetylester hydrolase from Corynebacterium glutamicum
分子名称: CHLORIDE ION, GLYCEROL, Homoserine O-acetyltransferase, ...
著者Niefind, K, Toelzer, C, Altenbuchner, J, Watzlawick, H.
登録日2015-08-12
公開日2015-12-09
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A novel esterase subfamily with alpha / beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases.
Febs Lett., 590, 2016
8GQM
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BU of 8gqm by Molmil
Crystal structure of Thiolase complexed with acetyl coenzyme A
分子名称: ACETYL COENZYME *A, GLYCEROL, Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
8GQK
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BU of 8gqk by Molmil
Crystal structure of Thiolase from Pseudomonas aeruginosa PAO1
分子名称: CITRIC ACID, Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
5D85
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BU of 5d85 by Molmil
Staphyloferrin B precursor biosynthetic enzyme SbnA bound to aminoacrylate intermediate
分子名称: 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, CITRATE ANION, GLYCEROL, ...
著者Kobylarz, M.J, Grigg, J.C, Liu, Y, Lee, M.S.F, Heinrichs, D.E, Murphy, M.E.P.
登録日2015-08-15
公開日2016-02-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis.
Biochemistry, 55, 2016
8GQI
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BU of 8gqi by Molmil
Structure of Thiolase from Pseudomonas aeruginosa PAO1
分子名称: GLYCEROL, Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
8GQJ
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BU of 8gqj by Molmil
Structure of Thiolase from Pseudomonas aeruginosa PAO1
分子名称: GLYCEROL, NONAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ...
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
2IB9
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BU of 2ib9 by Molmil
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-11
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
8GQF
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BU of 8gqf by Molmil
Crystal structure of Thiolase
分子名称: GLYCEROL, Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
6SLL
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BU of 6sll by Molmil
Diaminobutyrate acetyltransferase EctA from Paenibacillus lautus in complex with its substrate L-2,4-diaminobutyric acid (DAB) and coenzyme A
分子名称: 2,4-DIAMINOBUTYRIC ACID, COENZYME A, L-2,4-diaminobutyric acid acetyltransferase, ...
著者Richter, A.A, Kobus, S, Czech, L, Hoeppner, A, Bremer, E, Smits, S.H.J.
登録日2019-08-20
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine.
J.Biol.Chem., 295, 2020
8GQH
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BU of 8gqh by Molmil
Structure of Thiolase from Pseudomonas aeruginosa PAO1
分子名称: GLYCEROL, Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
8GQN
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BU of 8gqn by Molmil
X-ray structure of thiolase with CoA
分子名称: COENZYME A, Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
2IBY
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BU of 2iby by Molmil
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-12
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
8GQL
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BU of 8gql by Molmil
X-ray structure of Thiolase from Pseudomonas aeruginosa PAO1
分子名称: GLYCEROL, Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
8GQG
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BU of 8gqg by Molmil
Crystal structure of Thioloase from Pseudomonas aeruginosa PAO1
分子名称: Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
2I00
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BU of 2i00 by Molmil
Crystal structure of acetyltransferase (GNAT family) from Enterococcus faecalis
分子名称: Acetyltransferase, GNAT family
著者Zhang, R, Zhou, M, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-08-09
公開日2006-09-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of the acetyltransferase (GNAT family) from Enterococcus faecalis
To be Published, 2006
2IB7
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BU of 2ib7 by Molmil
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-11
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
5D86
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BU of 5d86 by Molmil
Staphyloferrin B precursor biosynthetic enzyme SbnA Y152F variant
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, ...
著者Kobylarz, M.J, Grigg, J.C, Liu, Y, Lee, M.S.F, Heinrichs, D.E, Murphy, M.E.P.
登録日2015-08-15
公開日2016-02-03
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis.
Biochemistry, 55, 2016
5DBE
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BU of 5dbe by Molmil
Crystal structure of O-acetylserine sulfhydrylase from Haemophilus influenzae in complex with pre-reactive O-acetyl serine, alpha-aminoacrylate reaction intermediate and peptide inhibitor at the resolution of 2.25A
分子名称: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, C-terminal peptide from Serine acetyltransferase, Cysteine synthase, ...
著者Singh, A.K, Kaushik, A, Ekka, M.K, Kumaran, S.
登録日2015-08-21
公開日2015-09-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure Of O-Acetylserine Sulfhydrylase From Haemophilus Influenzae In Complex With Pre-Reactive O-Acetyl Serine, Alpha-Aminoacrylate Reactionintermediate And Peptide Inhibitor At The Resolution Of 2.25A
To Be Published

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件を2024-10-16に公開中

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