PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

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6PJR	Time-resolved structural snapshot of proteolysis by GlpG inside the membrane 分子名称: CHLORIDE ION, Peptide aldehyde inhibitor, Rhomboid protease GlpG 著者 Urban, S, Cho, S. 登録日 2019-06-28 公開日 2019-10-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019
8U47	Crystal structure of Bacteroides thetaiotaomicron VPI-5482 Endoglycosidase BT1285 分子名称: Endo-beta-N-acetylglucosaminidase, MAGNESIUM ION, PHOSPHATE ION 著者 Sastre, D.E, Sultana, N, Sundberg, E.J. 登録日 2023-09-09 公開日 2024-05-29 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate. Nat Commun, 15, 2024
6PLI	Crystal Structure of EcDsbA in a complex with purified oxadiazole 11 分子名称: 2-[4-(4-cyano-3-methylphenoxy)phenyl]-N-methyl-N-[2-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl]acetamide, COPPER (II) ION, Thiol:disulfide interchange protein DsbA 著者 Ilyichova, O.V, Bentley, M, Doak, B, Scanlon, M.J. 登録日 2019-07-01 公開日 2020-05-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiL X ). J.Med.Chem., 63, 2020
6Z1E	Crystal structure of the AAA domain of Rubisco Activase from Nostoc sp. (strain PCC 7120) 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Ribulose bisphosphate carboxylase/oxygenase activase 著者 Popilka, L, Bracher, A. 登録日 2020-05-13 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.454 Å) 主引用文献 Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes. Cell, 183, 2020
6YVW	HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with monocyclic BB-328 分子名称: 4-[(5-bromanyl-4,6-dimethyl-pyridin-2-yl)amino]-4-oxidanylidene-butanoic acid, Egl nine homolog 1, FE (III) ION, ... 著者 Chowdhury, R, Banerji, B, Schofield, C.J. 登録日 2020-04-28 公開日 2020-12-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2. Sci Rep, 10, 2020
5JVV	Crystal structure and characterization an elongating GH family 16 beta-1,3-glucosyltransferase 分子名称: beta-1,3-glucosyltransferase 著者 Qin, Z, Yan, Q, Yang, S, Jiang, Z. 登録日 2016-05-11 公開日 2016-12-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.589 Å) 主引用文献 Catalytic Mechanism of a Novel Glycoside Hydrolase Family 16 "Elongating" beta-Transglycosylase J. Biol. Chem., 292, 2017
6BVC	Crystal structure of AAC(3)-Ia in complex with coenzyme A 分子名称: 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Aminoglycoside-(3)-N-acetyltransferase, CHLORIDE ION, ... 著者 Stogios, P.J, Evdokimova, E, Wawrzak, Z, Savchenko, A, Joachimiak, A, Satchell, K, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-12-12 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.808 Å) 主引用文献 To be published To Be Published
6CAF	High Resolution Structure of Concanavalin B from Jack Bean (Canavalia ensiformis), A Chitinase-like Protein 分子名称: Concanavalin B 著者 McPherson, A. 登録日 2018-01-30 公開日 2018-03-28 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 High Resolution Structure of Concanavalin B from Jack Bean (Canavalia ensiformis), a Chitinase-like Protein To be published
6P9S	E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 7 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
6Q4D	CDK2 in complex with FragLite31 分子名称: 2-(4-bromanyl-2-methoxy-phenyl)ethanoic acid, Cyclin-dependent kinase 2 著者 Wood, D.J, Martin, M.P, Noble, M.E.M. 登録日 2018-12-05 公開日 2019-03-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
8W68	Crystal structure of Q9PR55 at pH 6.0 (use NMR model) 分子名称: Uncharacterized protein UU089.1 著者 Hsu, M.F, Ko, T.P, Huang, K.F, Chen, Y.R, Huang, J.S, Hsu, S.T.D. 登録日 2023-08-28 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure, dynamics, and stability of the smallest and most complex 7 1 protein knot. J.Biol.Chem., 300, 2023
6Q55	Crystal structure of Cryptosporidium hominis CPSF3 in complex with Compound 61 分子名称: 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-trien-5-yl]propanoic acid, Cleavage and Polyadenylation Specificity Factor 3 (CPSF3), GLYCEROL, ... 著者 Palencia, A, Swale, C. 登録日 2018-12-07 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection. Sci Transl Med, 11, 2019
5K7E	The structure of pistol ribozyme, soaked with Mn2+ 分子名称: DNA/RNA 11-MER, MANGANESE (II) ION, RNA 47-MER 著者 Ren, A, Patel, D. 登録日 2016-05-26 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.27 Å) 主引用文献 Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage. Nat.Chem.Biol., 12, 2016
5K85	Crystal Structure of Acetyl-CoA Synthetase in Complex with Adenosine-5'-propylphosphate and Coenzyme A from Cryptococcus neoformans H99 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-MONOPHOSPHATE-PROPYL ESTER, Acetyl-coenzyme A synthetase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID), Fox III, D, Delker, S.L, Potts, K.T, Lorimer, D.D, Edwards, T.E, Mutz, M.W, SSGCID 登録日 2016-05-27 公開日 2016-08-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 CRYSTAL STRUCTURE OF ACETYL-COA SYNTHETASE IN COMPLEX WITH ADENOSINE-5'-PROPYLPHOSPHATE AND COENZYME A FROM CRYPTOCOCCUS NEOFORMANS H99 To Be Published
6D82	Structure of the Bovine p85a BH domain 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION 著者 Moore, S.A, Marshall, J.D, Anderson, D.H. 登録日 2018-04-25 公開日 2018-05-23 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (2.407 Å) 主引用文献 Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation. Sci Rep, 8, 2018
6GIG	Structural insights into AapA1 toxin 分子名称: AapA1 著者 Salgado, G.F, Korkut, D.N. 登録日 2018-05-11 公開日 2019-09-11 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Structural insights into the AapA1 toxin of Helicobacter pylori. Biochim Biophys Acta Gen Subj, 1864, 2020
6QDF	Leishmania major N-myristoyltransferase in complex with thienopyrimidine inhibitor IMP-0000096 分子名称: 3-[[6-tert-butyl-2-[methyl-[(3S)-1-methylpyrrolidin-3-yl]amino]thieno[3,2-d]pyrimidin-4-yl]-methyl-amino]propanenitrile, Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, ... 著者 Brannigan, J.A. 登録日 2019-01-01 公開日 2020-05-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes. J.Med.Chem., 63, 2020
6YYM	Structure of S. pombe Mei2 RRM3 domain bound to RNA 分子名称: Meiosis protein mei2, RNA (5'-R(*GP*CP*UP*UP*UP*UP*UP*GP*UP*UP*CP*G)-3') 著者 Hazra, D, Graille, M. 登録日 2020-05-05 公開日 2020-12-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 A scaffold lncRNA shapes the mitosis to meiosis switch. Nat Commun, 12, 2021
6GWD	Tubulin:iiH5 alphaRep complex 分子名称: ALPHA-TUBULIN, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Gigant, B, Campanacci, V. 登録日 2018-06-22 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Selection and Characterization of Artificial Proteins Targeting the Tubulin alpha Subunit. Structure, 27, 2019
6QD9	Leishmania major N-myristoyltransferase in complex with thienopyrimidine inhibitor IMP-0000065 分子名称: 3-[[2-[3-(dimethylamino)propyl-methyl-amino]thieno[3,2-d]pyrimidin-4-yl]-methyl-amino]propanenitrile, Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, ... 著者 Brannigan, J.A. 登録日 2019-01-01 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes. J.Med.Chem., 63, 2020
6QDH	Leishmania major N-myristoyltransferase in complex with quinazoline inhibitor IMP-0000906 分子名称: 4-[ethyl(methyl)amino]-2-[methyl-(1-methylpiperidin-4-yl)amino]-~{N}-(1,3,5-trimethylpyrazol-4-yl)quinazoline-6-sulfonamide, Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, ... 著者 Brannigan, J.A. 登録日 2019-01-01 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes. J.Med.Chem., 63, 2020
8BHE	K141H and S142H double mutant of hGSTA1-1 分子名称: Glutathione S-transferase A1 著者 Papageorgiou, A.C, Poudel, N. 登録日 2022-10-31 公開日 2023-03-08 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 A Key Role in Catalysis and Enzyme Thermostability of a Conserved Helix H5 Motif of Human Glutathione Transferase A1-1. Int J Mol Sci, 24, 2023
6GT2	Reduced copper nitrite reductase from Achromobacter cycloclastes determined by serial femtosecond rotation crystallography 分子名称: COPPER (II) ION, Copper-containing nitrite reductase, MALONATE ION 著者 Halsted, T.P, Yamashita, K, Gopalasingam, C.C, Shenoy, R.T, Hirata, K, Ago, H, Ueno, G, Eady, R.R, Antonyuk, S.V, Yamamoto, M, Hasnain, S.S. 登録日 2018-06-15 公開日 2019-07-03 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Catalytically important damage-free structures of a copper nitrite reductase obtained by femtosecond X-ray laser and room-temperature neutron crystallography. Iucrj, 6, 2019
6YTD	CLK1 V324A mutant bound with benzothiazole Tg003 (Cpd 2) 分子名称: (1~{Z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one, Dual specificity protein kinase CLK1 著者 Schroeder, M, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2020-04-24 公開日 2020-07-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 DFG-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing a Basis for Rational Design of Kinase Inhibitor Selectivity. J.Med.Chem., 63, 2020
5JQN	NitN Amidase from Neterenkonia sp. AN1 after thrombin His-tag removal. 分子名称: Aliphatic amidase 著者 Sewell, B.T, Kimani, S.W, Weber, B.W. 登録日 2016-05-05 公開日 2016-05-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 QM/MM Modelling of Substrate Binding in the Amidase Active Site To Be Published

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