6AOD
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![BU of 6aod by Molmil](/molmil-images/mine/6aod) | FXIa antibody complex | 分子名称: | COBALT (II) ION, Coagulation factor XI, FXIa Antibody FAB Heavy Chain, ... | 著者 | Lolicato, M, Minor, D.L. | 登録日 | 2017-08-15 | 公開日 | 2018-03-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent. Structure, 26, 2018
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8TXN
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6PBH
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6PBN
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6BD9
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![BU of 6bd9 by Molmil](/molmil-images/mine/6bd9) | Saccharomyces cerevisiae acetohydroxyacid synthase | 分子名称: | Acetolactate synthase catalytic subunit, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Guddat, L.W, Lonhienne, T. | 登録日 | 2017-10-22 | 公開日 | 2017-11-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.982 Å) | 主引用文献 | High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism Chemistryselect, 2017
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5JTD
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6E7H
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5JTS
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![BU of 5jts by Molmil](/molmil-images/mine/5jts) | Structure of a beta-1,4-mannanase, SsGH134. | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Jin, Y, Petricevic, M, Goddard-Borger, E.D, Williams, S.J, Davies, G.J. | 登録日 | 2016-05-09 | 公開日 | 2016-11-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | A beta-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism. ACS Cent Sci, 2, 2016
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6AT9
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![BU of 6at9 by Molmil](/molmil-images/mine/6at9) | Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-A*0101 | 分子名称: | ALK, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | 登録日 | 2017-08-28 | 公開日 | 2018-03-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.9503 Å) | 主引用文献 | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. Front Immunol, 9, 2018
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8UFJ
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![BU of 8ufj by Molmil](/molmil-images/mine/8ufj) | Structure of M. mazei GS(R167L-A168G) apo form | 分子名称: | Glutamine synthetase, MAGNESIUM ION | 著者 | Schumacher, M.A. | 登録日 | 2023-10-04 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation. Nat Commun, 14, 2023
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7ZSZ
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5KC6
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6XLO
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![BU of 6xlo by Molmil](/molmil-images/mine/6xlo) | Crystal structure of bRaf in complex with inhibitor | 分子名称: | 3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide, IODIDE ION, Serine/threonine-protein kinase B-raf | 著者 | Yin, J, Eigenbrot, C, Wang, W. | 登録日 | 2020-06-28 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | 主引用文献 | Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3 H )-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor. J.Med.Chem., 64, 2021
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6EOS
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![BU of 6eos by Molmil](/molmil-images/mine/6eos) | DPP8 - Apo, space group 19 | 分子名称: | Dipeptidyl peptidase 8 | 著者 | Ross, B.R, Huber, R. | 登録日 | 2017-10-10 | 公開日 | 2018-02-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6EAK
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6PJ9
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6EDH
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![BU of 6edh by Molmil](/molmil-images/mine/6edh) | Taurine:2OG dioxygenase (TauD) bound to the vanadyl ion, taurine, and succinate | 分子名称: | 2-AMINOETHANESULFONIC ACID, ACETATE ION, Alpha-ketoglutarate-dependent taurine dioxygenase, ... | 著者 | Davis, K.M, Altmyer, M, Boal, A.K. | 登録日 | 2018-08-09 | 公開日 | 2019-08-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.73000407 Å) | 主引用文献 | Structure of a Ferryl Mimic in the Archetypal Iron(II)- and 2-(Oxo)-glutarate-Dependent Dioxygenase, TauD. Biochemistry, 58, 2019
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5K5U
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5K63
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![BU of 5k63 by Molmil](/molmil-images/mine/5k63) | Crystal structure of N-terminal amidase C187S | 分子名称: | ASPARAGINE, GLYCINE, Nta1p | 著者 | Kim, M.K, Oh, S.-J, Lee, B.-G, Song, H.K. | 登録日 | 2016-05-24 | 公開日 | 2017-01-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5K6R
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![BU of 5k6r by Molmil](/molmil-images/mine/5k6r) | Crystal structure of Arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Acetolactate synthase, ... | 著者 | Garcia, M.D, Lonhienne, T, Guddat, L.W. | 登録日 | 2016-05-25 | 公開日 | 2017-02-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.734 Å) | 主引用文献 | Comprehensive understanding of acetohydroxyacid synthase inhibition by different herbicide families. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5K14
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![BU of 5k14 by Molmil](/molmil-images/mine/5k14) | HIV-1 Reverse Transcriptase in complex with a 2,6-difluorophenyl DAPY analog | 分子名称: | 4-{[4-(2,6-difluoro-4-methoxybenzene-1-carbonyl)pyrimidin-2-yl]amino}benzonitrile, HIV-1 reverse transcriptase (isolate LW123), HIV-1 reverse transcriptase(isolate HXB2) | 著者 | Lansdon, E.B. | 登録日 | 2016-05-17 | 公開日 | 2016-06-29 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Novel (2,6-difluorophenyl)(2-(phenylamino)pyrimidin-4-yl)methanones with restricted conformation as potent non-nucleoside reverse transcriptase inhibitors against HIV-1. Eur.J.Med.Chem., 122, 2016
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6PML
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6EK8
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7ZM9
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![BU of 7zm9 by Molmil](/molmil-images/mine/7zm9) | Ketosynthase domain 3 of Brevibacillus Brevis orphan BGC11 | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Putative polyketide synthase | 著者 | Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. | 登録日 | 2022-04-19 | 公開日 | 2022-09-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
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5K6F
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![BU of 5k6f by Molmil](/molmil-images/mine/5k6f) | Crystal structure of prefusion-stabilized RSV F single-chain 9-19 DS-Cav1 variant. | 分子名称: | Fusion glycoprotein F0 | 著者 | Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-08-10 | 最終更新日 | 2016-09-21 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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