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5KQ1
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BU of 5kq1 by Molmil
Crystal structure of S. pombe Dcp1/Dcp2 in complex with H. sapiens PNRC2
分子名称: Proline-rich nuclear receptor coactivator 2, mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1
著者Mugridge, J.S, Ziemniak, M, Jemielity, J, Gross, J.D.
登録日2016-07-05
公開日2016-10-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.002 Å)
主引用文献Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
Nat.Struct.Mol.Biol., 23, 2016
5J3Y
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BU of 5j3y by Molmil
Crystal structure of S. pombe Dcp2:Dcp1 mRNA decapping complex
分子名称: mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1
著者Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
登録日2016-03-31
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.288 Å)
主引用文献Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
5J3T
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BU of 5j3t by Molmil
Crystal structure of S. pombe Dcp2:Dcp1:Edc1 mRNA decapping complex
分子名称: Edc1, FORMIC ACID, MAGNESIUM ION, ...
著者Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
登録日2016-03-31
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
5IW5
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BU of 5iw5 by Molmil
Crystal structure of E. coli NudC in complex with NMN
分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, NADH pyrophosphatase, ZINC ION
著者Li, S, Du, J, Patel, D.J.
登録日2016-03-22
公開日2016-07-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and function of the bacterial decapping enzyme NudC
Nat.Chem.Biol., 12, 2016
5IW4
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BU of 5iw4 by Molmil
Crystal structure of E. coli NudC in complex with NAD
分子名称: NADH pyrophosphatase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
著者Li, S, Du, J, Patel, D.J.
登録日2016-03-22
公開日2016-07-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and function of the bacterial decapping enzyme NudC.
Nat.Chem.Biol., 12, 2016
5ISY
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BU of 5isy by Molmil
Crystal structure of Nudix family protein with NAD
分子名称: NADH pyrophosphatase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
著者Zhang, D, Guan, Z, Zou, T, Yin, P.
登録日2016-03-15
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.354 Å)
主引用文献Structural basis of prokaryotic NAD-RNA decapping by NudC
Cell Res., 26, 2016
5I8U
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BU of 5i8u by Molmil
Crystal Structure of the RV1700 (MT ADPRASE) E142Q mutant
分子名称: ADP-ribose pyrophosphatase, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ...
著者Thirawatananond, P, Kang, L.-W, Amzel, L.M, Gabelli, S.B.
登録日2016-02-19
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Kinetic and mutational studies of the adenosine diphosphate ribose hydrolase from Mycobacterium tuberculosis.
J. Bioenerg. Biomembr., 48, 2016
5HZX
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BU of 5hzx by Molmil
Crystal structure of zebrafish MTH1 in complex with TH588
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Narwal, M, Gustafsson, R, Brautigam, L, Pudelko, L, Jemth, A.-S, Gad, H, Karsten, S, Carreras-Puigvert, J, Homan, E, Berndt, C, Berglund, U.W, Helleday, T, Stenmark, P.
登録日2016-02-03
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Hypoxic Signaling and the Cellular Redox Tumor Environment Determine Sensitivity to MTH1 Inhibition.
Cancer Res., 76, 2016
5GP0
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BU of 5gp0 by Molmil
Crystal structure of geraniol-NUDX1 complex
分子名称: GERANYL DIPHOSPHATE, GLYCEROL, Nudix hydrolase 1
著者Liu, J, Guan, Z, Zou, T, Yin, P.
登録日2016-07-30
公開日2017-10-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Structural Insights into the Substrate Recognition Mechanism of Arabidopsis GPP-Bound NUDX1 for Noncanonical Monoterpene Biosynthesis.
Mol Plant, 11, 2018
5GHQ
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BU of 5ghq by Molmil
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP under high concentrations of 2-oxo-dATP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.181 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHP
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BU of 5ghp by Molmil
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.192 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHO
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BU of 5gho by Molmil
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 8-oxo-dGTP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.191 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHN
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BU of 5ghn by Molmil
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.391 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHM
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BU of 5ghm by Molmil
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 7.0
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHJ
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BU of 5ghj by Molmil
Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHI
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BU of 5ghi by Molmil
Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.211 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GGD
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BU of 5ggd by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with phosphate and magnesium ions (excess magnesium, II)
分子名称: Hydrolase, NUDIX family protein, MAGNESIUM ION, ...
著者Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
登録日2016-06-15
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
5GGC
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BU of 5ggc by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with phosphate and magnesium ions (excess magnesium, I)
分子名称: Hydrolase, NUDIX family protein, MAGNESIUM ION, ...
著者Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
登録日2016-06-15
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
5GGB
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BU of 5ggb by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGDP
分子名称: 2'-deoxy-8-oxoguanosine 5'-(trihydrogen diphosphate), Hydrolase, NUDIX family protein
著者Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
登録日2016-06-15
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
5GGA
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BU of 5gga by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-GDP, 8-oxo-GMP and pyrophosphate
分子名称: Hydrolase, NUDIX family protein, MAGNESIUM ION, ...
著者Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
登録日2016-06-15
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
5GG9
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BU of 5gg9 by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-GTP, 8-oxo-GMP and pyrophosphate
分子名称: 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, Hydrolase, NUDIX family protein, ...
著者Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
登録日2016-06-15
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
5GG8
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BU of 5gg8 by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP, 8-oxo-dGMP and pyrophosphate (II)
分子名称: 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Hydrolase, ...
著者Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
登録日2016-06-15
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
5GG7
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BU of 5gg7 by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP, 8-oxo-dGMP and pyrophosphate (I)
分子名称: 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Hydrolase, ...
著者Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
登録日2016-06-15
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
5GG6
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BU of 5gg6 by Molmil
Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP
分子名称: 1,2-ETHANEDIOL, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
著者Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
登録日2016-06-15
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
5GG5
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BU of 5gg5 by Molmil
Crystal structure of Mycobacterium smegmatis MutT1
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Hydrolase, ...
著者Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M.
登録日2016-06-15
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017

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