PDB: 45331 件ウェブページステータス検索Chemie searchBIRD

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6EUT	The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (KSK67) 分子名称: (3~{R})-8-cyclopropyl-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Begum, A, Hall, M, Grundstrom, C, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. 登録日 2017-10-31 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J. Med. Chem., 61, 2018
6EUZ	The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK37) 分子名称: (3~{R})-8-methoxy-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid, ISOPROPYL ALCOHOL, Listeriolysin positive regulatory factor A, ... 著者 Begum, A, Hall, M, Grundstrom, C, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. 登録日 2017-10-31 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J. Med. Chem., 61, 2018
4LGD	Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ras association domain family member 5, ... 著者 Luo, X, Ni, L, Tomchick, D.R. 登録日 2013-06-27 公開日 2013-09-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5. Structure, 21, 2013
6ESQ	Structure of the acetoacetyl-CoA thiolase/HMG-CoA synthase complex from Methanothermococcus thermolithotrophicus soaked with acetyl-CoA 分子名称: CHLORIDE ION, COENZYME A, HydroxyMethylGlutaryl-CoA synthase, ... 著者 Voegeli, B, Engilberge, S, Girard, E, Riobe, F, Maury, O, Erb, J.T, Shima, S, Wagner, T. 登録日 2017-10-24 公開日 2018-03-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Archaeal acetoacetyl-CoA thiolase/HMG-CoA synthase complex channels the intermediate via a fused CoA-binding site. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EUU	The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (KSK29) 分子名称: (3~{R})-8-cyclopropyl-5-oxidanylidene-7-(quinolin-3-ylmethyl)-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid, ISOPROPYL ALCOHOL, Listeriolysin positive regulatory factor A, ... 著者 Begum, A, Hall, M, Grundstrom, C, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. 登録日 2017-10-31 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J. Med. Chem., 61, 2018
6EZI	PDZK1 domain 4 in complex with C-terminal peptide of human PepT2. 分子名称: GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Solute carrier family 15 member 2 著者 Loew, C, Flayhan, A, Pieprzyk, J. 登録日 2017-11-15 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.503321 Å) 主引用文献 Probing the Architecture of a Multi-PDZ Domain Protein: Structure of PDZK1 in Solution. Structure, 26, 2018
6A0U	Homoserine dehydrogenase K195A mutant from Thermus thermophilus HB8 complexed with HSE and NADP+ 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, FORMIC ACID, GLYCEROL, ... 著者 Akai, S, Ikushiro, H, Sawai, T, Yano, T, Kamiya, N, Miyahara, I. 登録日 2018-06-06 公開日 2018-11-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 The crystal structure of homoserine dehydrogenase complexed with l-homoserine and NADPH in a closed form J. Biochem., 165, 2019
4KLI	DNA polymerase beta matched product complex with Mg2+, 90 s 分子名称: 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Freudenthal, B.D, Beard, W.A, Shock, D.D, Wilson, S.H. 登録日 2013-05-07 公開日 2013-07-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.597 Å) 主引用文献 Observing a DNA polymerase choose right from wrong. Cell(Cambridge,Mass.), 154, 2013
6F5V	Crystal structure of the prephenate aminotransferase from Arabidopsis thaliana 分子名称: Bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase, CITRIC ACID, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Cobessi, D, Robin, A, Giustini, C, Graindorge, M, Matringe, M. 登録日 2017-12-03 公開日 2019-03-13 最終更新日 2019-06-12 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1 beta aspartate aminotransferase. Febs J., 286, 2019
6F9M	The LIPY/F-motif in an intracellular subtilisin protease is involved in inhibition 分子名称: ACETATE ION, SODIUM ION, Serine protease, ... 著者 Bjerga, G.E.K, Larsen, O, Arsin, H, Williamson, A.K, Garcia-Moyano, A, Leiros, I, Puntervoll, P. 登録日 2017-12-14 公開日 2018-06-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.298 Å) 主引用文献 Mutational analysis of the pro-peptide of a marine intracellular subtilisin protease supports its role in inhibition. Proteins, 86, 2018
3QXT	Structure of an Anti-Methotrexate CDR1-3 Graft VHH Antibody in Complex with Methotrexate 分子名称: Anti-Methotrexate CDR1-3 Graft VHH, METHOTREXATE, SODIUM ION 著者 Fanning, S.W, Horn, J.R. 登録日 2011-03-02 公開日 2011-07-06 最終更新日 2013-09-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop. Protein Sci., 20, 2011
6EYP	X-ray structure of the unliganded uridine phosphorylase from Vibrio cholerae at 1.22A 分子名称: GLYCEROL, MAGNESIUM ION, SODIUM ION, ... 著者 Prokofev, I.I, Balaev, V.V, Gabdoulkhakov, A.G, Betzel, C, Lashkov, A.A. 登録日 2017-11-13 公開日 2018-11-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 X-ray structure of the unliganded uridine phosphorylase from Vibrio cholerae at 1.22A To Be Published
3AXG	Structure of 6-aminohexanoate-oligomer hydrolase 分子名称: Endotype 6-aminohexanoat-oligomer hydrolase, SODIUM ION 著者 Negoro, S, Shibata, N, Tanaka, Y, Yasuhira, K, Shibata, H, Hashimoto, H, Lee, Y.H, Ohshima, S, Santa, R, Mochiji, K, Goto, Y, Ikegami, T, Nagai, K, Kato, D, Takeo, M, Higuchi, Y. 登録日 2011-04-04 公開日 2011-12-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Three-dimensional structure of nylon hydrolase and mechanism of nylon-6 hydrolysis J.Biol.Chem., 287, 2012
6EXK	The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK206) - unfolded HTH motif 分子名称: ISOPROPYL ALCOHOL, Listeriolysin regulatory protein, SODIUM ION, ... 著者 Hall, M, Grundstrom, C, Begum, A, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. 登録日 2017-11-08 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J. Med. Chem., 61, 2018
2FBL	The crystal structure of the hypothetical protein NE1496 分子名称: SODIUM ION, hypothetical protein NE1496 著者 Lunin, V.V, Skarina, T, Onopriyenko, O, Binkowski, T.A, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) 登録日 2005-12-09 公開日 2005-12-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The crystal structure of the hypothetical protein NE1496 To be Published
6BVE	Triosephosphate isomerase of Synechocystis in complex with 2-Phosphoglycolic acid 分子名称: 2-PHOSPHOGLYCOLIC ACID, SODIUM ION, Triosephosphate isomerase 著者 Jimenez-Sandoval, P, Castro-Torres, E, Brieba, L.G. 登録日 2017-12-12 公開日 2018-12-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural Basis for the Limited Response to Oxidative and Thiol-Conjugating Agents by Triosephosphate Isomerase From the Photosynthetic BacteriaSynechocystis. Front Mol Biosci, 5, 2018
6BTE	DNA Polymerase Beta I260Q Binary Complex 分子名称: CHLORIDE ION, DNA Downstream Strand, DNA Primer Strand, ... 著者 Eckenroth, B.E, Doublie, S. 登録日 2017-12-06 公開日 2018-09-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity. Nucleic Acids Res., 46, 2018
6AJX	Crystal structure of BRD4 in complex with isoliquiritigenin in the absence of DMSO 分子名称: 2',4,4'-TRIHYDROXYCHALCONE, Bromodomain-containing protein 4, SODIUM ION 著者 Yokoyama, T, Matsumoto, K, Nabeshima, Y, Mizuguchi, M. 登録日 2018-08-28 公開日 2019-06-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.887 Å) 主引用文献 Structural and thermodynamic characterization of the binding of isoliquiritigenin to the first bromodomain of BRD4. Febs J., 286, 2019
4J0N	Crystal structure of a manganese dependent isatin hydrolase 分子名称: CALCIUM ION, Isatin hydrolase B, MANGANESE (II) ION, ... 著者 Bjerregaard-Andersen, K, Sommer, T, Jensen, J.K, Jochimsen, B, Etzerodt, M, Morth, J.P. 登録日 2013-01-31 公開日 2013-02-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A proton wire and water channel revealed in the crystal structure of isatin hydrolase. J.Biol.Chem., 289, 2014
6AID	Structural insights into the unique polylactate degrading mechanism of Thermobifida alba cutinase 分子名称: CALCIUM ION, Esterase, LACTIC ACID, ... 著者 Kitadokoro, K, Kakara, M, Matsui, S, Osokoshi, R, Thumarat, U, Kawai, F, Kamitani, S. 登録日 2018-08-22 公開日 2019-02-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural insights into the unique polylactate-degrading mechanism of Thermobifida alba cutinase. Febs J., 286, 2019
4LS8	Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a covalent complex with cerulenin 分子名称: (3R,7E,10E)-3-hydroxy-4-oxododeca-7,10-dienamide, 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase 2, ... 著者 Trajtenberg, F, Larrieux, N, Buschiazzo, A. 登録日 2013-07-22 公開日 2014-04-02 最終更新日 2014-06-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights into bacterial resistance to cerulenin. Febs J., 281, 2014
6C39	Apo crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) 分子名称: SODIUM ION, SULFATE ION, Serine-type D-Ala-D-Ala carboxypeptidase, ... 著者 Alexander, J.A.N, Strynadka, N.C.J. 登録日 2018-01-09 公開日 2018-11-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 293, 2018
2X8J	Intracellular subtilisin precursor from B. clausii 分子名称: GLYCEROL, INTRACELLULAR SUBTILISIN PROTEASE, PENTAETHYLENE GLYCOL, ... 著者 Vedodova, J, Gamble, M, Ariza, A, Dodson, E, Jones, D.D, Wilson, K.S. 登録日 2010-03-09 公開日 2010-08-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Crystal structure of an intracellular subtilisin reveals novel structural features unique to this subtilisin family. Structure, 18, 2010
6B4N	a hydroxymethyl functionality at the 4-position of the 2-phenyloxazole moiety of HIV-1 protease inhibitors involving the P2' ligands 分子名称: CHLORIDE ION, Protease, SODIUM ION, ... 著者 Wang, Y.-F, Agniswamy, J, Weber, I.T. 登録日 2017-09-27 公開日 2017-11-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Design, Synthesis, Biological Evaluation, and X-ray Studies of HIV-1 Protease Inhibitors with Modified P2' Ligands of Darunavir. ChemMedChem, 12, 2017
4KLQ	Observing a DNA polymerase choose right from wrong. 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*A)-3', ... 著者 Freudenthal, B.D, Beard, W.A, Shock, D.D, Wilson, S.H. 登録日 2013-05-07 公開日 2013-07-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Observing a DNA polymerase choose right from wrong. Cell(Cambridge,Mass.), 154, 2013

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