2IIM
 
 | | SH3 Domain of Human Lck | | 分子名称: | CALCIUM ION, Proto-oncogene tyrosine-protein kinase LCK, TETRAETHYLENE GLYCOL, ... | | 著者 | Romir, J, Egerer-Sieber, C, Muller, Y.A. | | 登録日 | 2006-09-28 | | 公開日 | 2006-11-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs.
J.Mol.Biol., 365, 2007
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2DYB
 | | The crystal structure of human p40(phox) | | 分子名称: | Neutrophil cytosol factor 4 | | 著者 | Honbou, K. | | 登録日 | 2006-09-08 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding.
Embo J., 26, 2007
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2DX1
 | | Crystal structure of RhoGEF protein Asef | | 分子名称: | Rho guanine nucleotide exchange factor 4 | | 著者 | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-08-22 | | 公開日 | 2007-01-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism
J.Biol.Chem., 282, 2007
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2J06
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2J05
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2DVJ
 | | phosphorylated Crk-II | | 分子名称: | V-crk sarcoma virus CT10 oncogene homolog, isoform a | | 著者 | Kobashigawa, Y, Inagaki, F. | | 登録日 | 2006-07-31 | | 公開日 | 2007-05-08 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat.Struct.Mol.Biol., 14, 2007
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2HDA
 | | Yes SH3 domain | | 分子名称: | Proto-oncogene tyrosine-protein kinase Yes, SULFATE ION | | 著者 | Camara-Artigas, A, Luque, I, Ruiz-Sanz, J, Mateo, P.L, Martin-Garcia, J.M. | | 登録日 | 2006-06-20 | | 公開日 | 2007-04-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic structure of the SH3 domain of the human c-Yes tyrosine kinase: Loop flexibility and amyloid aggregation.
Febs Lett., 581, 2007
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2DRK
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2DRM
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2H8H
 | | Src kinase in complex with a quinazoline inhibitor | | 分子名称: | N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE, Proto-oncogene tyrosine-protein kinase Src | | 著者 | Otterbein, L.R, Norman, R, Pauptit, R.A, Rowsell, S, Breed, J. | | 登録日 | 2006-06-07 | | 公開日 | 2006-11-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor.
J.Med.Chem., 49, 2006
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2DNU
 | | Solution structure of RSGI RUH-061, a SH3 domain from human | | 分子名称: | SH3 multiple domains 1 | | 著者 | Ohashi, W, Hirota, H, Nagashima, T, Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-26 | | 公開日 | 2006-10-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of RSGI RUH-061, a SH3 domain from human
to be published
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2DMO
 | | Refined solution structure of the 1st SH3 domain from human Neutrophil cytosol factor 2 (NCF-2) | | 分子名称: | Neutrophil cytosol factor 2 | | 著者 | Tochio, N, Chikayama, E, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-22 | | 公開日 | 2006-05-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the 1st SH3 domain from human Neutrophil cytosol factor 2 (NCF-2)
To be Published
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2GQI
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2DL8
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2DL5
 | | Solution structure of the first SH3 domain of human KIAA0769 protein | | 分子名称: | KIAA0769 protein | | 著者 | Qin, X.R, Izumi, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-17 | | 公開日 | 2006-10-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the first SH3 domain of human KIAA0769 protein
To be published
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2DL4
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2GNC
 | | Crystal structure of srGAP1 SH3 domain in the slit-robo signaling pathway | | 分子名称: | SLIT-ROBO Rho GTPase-activating protein 1 | | 著者 | Li, X, Liu, Y, Gao, F, Bartlam, M, Wu, J.Y, Rao, Z. | | 登録日 | 2006-04-10 | | 公開日 | 2006-07-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis of Robo Proline-rich Motif Recognition by the srGAP1 Src Homology 3 Domain in the Slit-Robo Signaling Pathway
J.Biol.Chem., 281, 2006
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2DIL
 | | Solution structure of the SH3 domain of the human Proline-serine-threonine phosphatase-interacting protein 1 | | 分子名称: | Proline-serine-threonine phosphatase-interacting protein 1 | | 著者 | Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-03-30 | | 公開日 | 2007-02-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the SH3 domain of the human Proline-serine-threonine phosphatase-interacting protein 1
To be Published
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2CDT
 | | alpha-SPECTRIN SH3 DOMAIN A56S MUTANT | | 分子名称: | SPECTRIN ALPHA CHAIN | | 著者 | Casares, S, Camara-Artigas, A, Vega, M.C, Lopez-Mayorga, O, Conejero-Lara, F. | | 登録日 | 2006-01-27 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Cooperative Propagation of Local Stability Changes from Low-Stability and High-Stability Regions in a SH3 Domain.
Proteins: Struct., Funct., Bioinf., 67, 2007
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2FRY
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2FO0
 | | Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase | | 分子名称: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... | | 著者 | Nagar, B, Hantschel, O, Seeliger, M, Davies, J.M, Weis, W.I, Superti-Furga, G, Kuriyan, J. | | 登録日 | 2006-01-12 | | 公開日 | 2006-03-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase.
Mol.Cell, 21, 2006
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2D8J
 | | Solution structure of the SH3 domain of Fyn-related kinase | | 分子名称: | fyn-related kinase | | 著者 | Qin, X.R, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-12-06 | | 公開日 | 2006-06-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the SH3 domain of Fyn-related kinase
TO BE PUBLISHED
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2F2V
 | | alpha-spectrin SH3 domain A56G mutant | | 分子名称: | FORMIC ACID, Spectrin alpha chain, brain | | 著者 | Camara-Artigas, A, Conejero-Lara, F, Casares, S, Lopez-Mayorga, O, Vega, C. | | 登録日 | 2005-11-18 | | 公開日 | 2006-10-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain
Proteins, 67, 2007
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2F2W
 | | alpha-spectrin SH3 domain R21A mutant | | 分子名称: | SULFATE ION, Spectrin alpha chain, brain | | 著者 | Camara-Artigas, A, Conejero-Lara, F, Casares, S, Lopez-Mayorga, O, Vega, C. | | 登録日 | 2005-11-18 | | 公開日 | 2006-10-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain
Proteins, 67, 2007
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2F2X
 | | alpha-spectrin SH3 domain R21G mutant | | 分子名称: | SULFATE ION, Spectrin alpha chain, brain | | 著者 | Camara-Artigas, A, Conejero-Lara, F, Casares, S, Lopez-Mayorga, O, Vega, C. | | 登録日 | 2005-11-18 | | 公開日 | 2006-10-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain
Proteins, 67, 2007
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