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5I4N
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BU of 5i4n by Molmil
Crystal Structure of the E596A V617F Mutant JAK2 Pseudokinase Domain Bound to Mg-ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Shiau, A.K, Motamedi, A.
登録日2016-02-12
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 alpha C helix.
Biochem.J., 473, 2016
5IDM
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BU of 5idm by Molmil
Bifunctional histidine kinase CckA (domain, CA) in complex with c-di-GMP and AMPPNP/Mg2+
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Cell cycle histidine kinase CckA, MAGNESIUM ION, ...
著者Dubey, B.N, Schirmer, T.
登録日2016-02-24
公開日2016-10-05
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking.
Sci Adv, 2, 2016
1AEV
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BU of 1aev by Molmil
INTRODUCTION OF NOVEL SUBSTRATE OXIDATION INTO CYTOCHROME C PEROXIDASE BY CAVITY COMPLEMENTATION: OXIDATION OF 2-AMINOTHIAZOLE AND COVALENT MODIFICATION OF THE ENZYME (2-AMINOTHIAZOLE)
分子名称: 2-AMINOTHIAZOLE, CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
著者Musah, R.A, Fitzgerald, M.M, Jensen, G.M, Mcree, D.E, Goodin, D.B.
登録日1997-02-25
公開日1997-09-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Introduction of novel substrate oxidation into cytochrome c peroxidase by cavity complementation: oxidation of 2-aminothiazole and covalent modification of the enzyme.
Biochemistry, 36, 1997
6S08
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BU of 6s08 by Molmil
Crystal Structure of Properdin (TSR domains N1 & 456)
分子名称: Properdin, SODIUM ION, TRIETHYLENE GLYCOL, ...
著者van den Bos, R.M, Pearce, N.M, Gros, P.
登録日2019-06-14
公開日2019-09-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b.
Front Immunol, 10, 2019
5NFO
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BU of 5nfo by Molmil
Human JMJD7 in complex with Mn and 2OG in the P21212 form
分子名称: 2-OXOGLUTARIC ACID, GLYCEROL, JmjC domain-containing protein 7, ...
著者Chowdhury, R, Markolovic, S, Schofield, C.J.
登録日2017-03-14
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.173 Å)
主引用文献(3S)-Lysyl hydroxylation of TRAFAC GTPases is catalyzed by the human Jumonji-C oxygenase JMJD7.
To Be Published
4B2A
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BU of 4b2a by Molmil
Structure of the factor Xa-like trypsin variant triple-Ala (TGA) in complex with eglin C
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ...
著者Menzel, A, Neumann, P, Stubbs, M.T.
登録日2012-07-13
公開日2012-08-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Thermodynamic signatures in macromolecular interactions involving conformational flexibility.
Biol.Chem., 395, 2014
8H2D
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BU of 8h2d by Molmil
The hypothetical protein from Mycobacterium tuberculosis mutant - E47A
分子名称: Uncharacterized protein Rv1546
著者Kim, D.H, Na, Y, Lee, B.J.
登録日2022-10-05
公開日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Domain swapping of the C-terminal helix promotes the dimerization of a novel ribonuclease protein from Mycobacterium tuberculosis.
Protein Sci., 32, 2023
6VJP
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BU of 6vjp by Molmil
Structure of Staphylococcus aureus peptidoglycan O-acetyltransferase A (OatA) C-terminal catalytic domain
分子名称: Acetyltransferase, SODIUM ION
著者Jones, C.J, Sychantha, D, Howell, P.L, Clarke, A.J.
登録日2020-01-16
公開日2020-05-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.711 Å)
主引用文献Structural basis for theO-acetyltransferase function of the extracytoplasmic domain of OatA fromStaphylococcus aureus.
J.Biol.Chem., 295, 2020
1UUZ
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BU of 1uuz by Molmil
IVY:A NEW FAMILY OF PROTEIN
分子名称: INHIBITOR OF VERTEBRATE LYSOZYME, LYSOZYME C
著者Abergel, C, Lembo, F, Byrne, D, Maza, C, Claverie, J.M.
登録日2004-01-12
公開日2004-01-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and Evolution of the Ivy Protein Family, Unexpected Lysozyme Inhibitors in Gram-Negative Bacteria.
Proc.Natl.Acad.Sci.USA, 104, 2007
6I9L
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BU of 6i9l by Molmil
JmjC domain-containing protein 5 (JMJD5) in complex with Mn and pyridine-2,4-dicarboxylic acid (2,4-PDCA)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, JmjC domain-containing protein 5, MANGANESE (II) ION, ...
著者Chowdhury, R, Islam, M.S, Schofield, C.J.
登録日2018-11-23
公開日2019-12-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5.
Sci Rep, 12, 2022
7Y5C
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BU of 7y5c by Molmil
Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Saw, W.-G, Wong, C.F, Grueber, G.
登録日2022-06-16
公開日2022-11-23
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors.
Antimicrob.Agents Chemother., 66, 2022
8U87
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BU of 8u87 by Molmil
Structural Basis of Human NOX5 Activation
分子名称: DODECANE, FLAVIN-ADENINE DINUCLEOTIDE, HEME B/C, ...
著者Cui, C, Jiang, M, Sun, J.
登録日2023-09-16
公開日2024-05-01
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Structural Basis of Human NOX5 Activation
To Be Published
7Y5D
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BU of 7y5d by Molmil
Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 3) (backbone)
分子名称: ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ...
著者Saw, W.-G, Wong, C.F, Grueber, G.
登録日2022-06-16
公開日2022-11-23
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors.
Antimicrob.Agents Chemother., 66, 2022
6F63
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BU of 6f63 by Molmil
Crystal structure of the SYCP1 C-terminal back-to-back assembly
分子名称: Synaptonemal complex protein 1
著者Dunce, J.M, Millan, C, Uson, I, Davies, O.R.
登録日2017-12-04
公開日2018-06-06
最終更新日2020-04-22
実験手法X-RAY DIFFRACTION (2.154 Å)
主引用文献Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly.
Nat. Struct. Mol. Biol., 25, 2018
1VRL
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BU of 1vrl by Molmil
MutY adenine glycosylase in complex with DNA and soaked adenine free base
分子名称: 5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*T)-3', ADENINE, ...
著者Fromme, J.C, Banerjee, A, Huang, S.J, Verdine, G.L.
登録日2005-03-08
公開日2005-03-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
Nature, 427, 2004
5LZP
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BU of 5lzp by Molmil
Binding of the C-terminal GQYL motif of the bacterial proteasome activator Bpa to the 20S proteasome
分子名称: Bacterial proteasome activator, Proteasome subunit alpha, Proteasome subunit beta
著者Bolten, M, Delley, C.L, Leibundgut, M, Boehringer, D, Ban, N, Weber-Ban, E.
登録日2016-09-30
公開日2016-11-23
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural Analysis of the Bacterial Proteasome Activator Bpa in Complex with the 20S Proteasome.
Structure, 24, 2016
6I9M
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BU of 6i9m by Molmil
JmjC domain-containing protein 5 (JMJD5) in complex with Mn and R-2-hydroxyglutarate
分子名称: (2R)-2-hydroxypentanedioic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ...
著者Chowdhury, R, Islam, M.S, Schofield, C.J.
登録日2018-11-23
公開日2019-12-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5.
Sci Rep, 12, 2022
7XD7
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BU of 7xd7 by Molmil
The pre-Tet-C state of wild-type Tetrahymena group I intron with 30nt 3'/5'-exon
分子名称: MAGNESIUM ION, SPERMIDINE, The pre-Tet-C state molecule of co-transcriptional folded wild-type Tetrahymena group I intron with 30nt 3'/5'-exon
著者Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z.
登録日2022-03-26
公開日2023-03-29
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing
Nat Catal, 2023
5XGE
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BU of 5xge by Molmil
Crystal structure of the PAS-GGDEF-EAL domain of PA0861 from Pseudomonas aeruginosa in complex with cyclic di-GMP
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Uncharacterized protein PA0861
著者Liu, C, Liew, C.W, Sreekanth, R, Lescar, J.
登録日2017-04-13
公開日2017-12-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa.
J. Bacteriol., 200, 2018
1BJ9
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BU of 1bj9 by Molmil
EFFECT OF UNNATURAL HEME SUBSTITUTION ON KINETICS OF ELECTRON TRANSFER IN CYTOCHROME C PEROXIDASE
分子名称: CYTOCHROME C PEROXIDASE, [7,12-DEACETYL-3,8,13,17-TETRAMETHYL-21H,23H-PORPHINE-2,18-DIPROPANOATO(2-)-N21,N22,N23,N24]-IRON
著者Miller, M.A, Kraut, J.
登録日1998-07-03
公開日1999-01-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Effect of Unnatural Heme Substitution on Kinetics of Electron Transfer in Cytochrome C Peroxidase
To be Published
7NCB
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BU of 7ncb by Molmil
Glutathione-S-transferase GliG mutant H26A
分子名称: Glutathione S-transferase GliG
著者Groll, M, Huber, E.M.
登録日2021-01-28
公開日2021-05-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Angew.Chem.Int.Ed.Engl., 60, 2021
7NCM
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BU of 7ncm by Molmil
Glutathione-S-transferase GliG mutant E82A
分子名称: 1,2-ETHANEDIOL, Glutathione S-transferase GliG
著者Groll, M, Huber, E.M.
登録日2021-01-29
公開日2021-05-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Angew.Chem.Int.Ed.Engl., 60, 2021
7NCU
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BU of 7ncu by Molmil
Glutathione-S-transferase GliG mutant K127G in complex with oxidized glutathione
分子名称: 1,2-ETHANEDIOL, Glutathione S-transferase GliG, OXIDIZED GLUTATHIONE DISULFIDE
著者Groll, M, Huber, E.M.
登録日2021-01-29
公開日2021-05-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Angew.Chem.Int.Ed.Engl., 60, 2021
7NC2
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BU of 7nc2 by Molmil
Glutathione-S-transferase GliG (space group P3221)
分子名称: Glutathione S-transferase GliG
著者Groll, M, Huber, E.M.
登録日2021-01-28
公開日2021-05-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Angew.Chem.Int.Ed.Engl., 60, 2021
7NC1
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BU of 7nc1 by Molmil
Glutathione-S-transferase GliG with partially disordered active site
分子名称: ACETATE ION, Glutathione S-transferase GliG
著者Groll, M, Huber, E.M.
登録日2021-01-28
公開日2021-05-12
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Angew.Chem.Int.Ed.Engl., 60, 2021

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