PDB: 13413 件ウェブページステータス検索Chemie searchBIRD

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2JEF	The Molecular Basis of Selectivity of Nucleotide Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase IV: Steady-state and Pre-steady-state and X-Ray Crystallography of Correct and Incorrect Pairing 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*DOC)-3', 5'-D(*TP*CP*AP*CP*BZGP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP CP*CP*C)-3', ... 著者 Eoff, R.L, Angel, K.C, Kosekov, I.D, Egli, M, Guengerich, F.P. 登録日 2007-01-17 公開日 2007-03-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus Solfataricus DNA Polymerase Dpo4: Steady-State and Pre-Steady-State Kinetics and X-Ray Crystallography of Correct and Incorrect Pairing. J.Biol.Chem., 282, 2007
5HHG	Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex 分子名称: Importin subunit alpha-1, RNA-directed RNA polymerase NS5 著者 Smith, K.M, Forwood, J.K. 登録日 2016-01-11 公開日 2016-05-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog., 12, 2016
2AU0	Unmodified preinsertion binary complex 分子名称: 5'-D(*CP*TP*AP*AP*CP*G*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', 5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', CALCIUM ION, ... 著者 Rechkoblit, O, Malinina, L, Cheng, Y, Kuryavyi, V, Broyde, S, Geacintov, N.E, Patel, D.J. 登録日 2005-08-26 公開日 2006-01-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion Plos Biol., 4, 2006
4DQS	Binary complex of Bacillus DNA Polymerase I Large Fragment and duplex DNA with rC in primer terminus paired with dG of template 分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase, ... 著者 Wang, W, Beese, L.S. 登録日 2012-02-16 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. J.Biol.Chem., 287, 2012
1YY7	Crystal structure of stringent starvation protein A (SspA), an RNA polymerase-associated transcription factor 分子名称: CITRIC ACID, stringent starvation protein A 著者 Hansen, A.-M, Gu, Y, Li, M, Andrykovitch, M, Waugh, D.S, Jin, D.J, Ji, X. 登録日 2005-02-23 公開日 2005-03-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Structural basis for the function of stringent starvation protein A as a transcription factor J.Biol.Chem., 280, 2005
4IH7	Hepatitis C Virus polymerase NS5B (BK) with fragment-based compounds 分子名称: 3-(3-tert-butylphenyl)pyridin-2(1H)-one, RNA-directed RNA polymerase, ZINC ION 著者 Harris, S.F, Wong, A. 登録日 2012-12-18 公開日 2013-07-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 De novo fragment design: a medicinal chemistry approach to fragment-based lead generation. J.Med.Chem., 56, 2013
1QTM	DDTTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS 分子名称: 5'-D(*AP*AP*AP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DT))-3', DNA POLYMERASE I, ... 著者 Li, Y, Mitaxov, V, Waksman, G. 登録日 1999-06-28 公開日 1999-08-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc.Natl.Acad.Sci.USA, 96, 1999
6UOM	Y271G DNA polymerase beta ternary complex with templating adenine and incoming r8-oxo-GTP 分子名称: 1,2-ETHANEDIOL, 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Smith, M.R, Freudenthal, B.D. 登録日 2019-10-15 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase beta. J.Biol.Chem., 295, 2020
4RQ3	Precatalytic ternary complex of Human DNA Polymerase Beta With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine (8-oxoG) and dATP in the presence of CaCl2 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ACETATE ION, CALCIUM ION, ... 著者 Vyas, R, Suo, Z. 登録日 2014-10-31 公開日 2015-04-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography. J.Am.Chem.Soc., 137, 2015
4RPX	Precatalytic ternary complex of Human DNA Polymerase Beta With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine (8-oxoG) and dCTP in the presence of CaCl2 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, ACETATE ION, CALCIUM ION, ... 著者 Vyas, R, Suo, Z. 登録日 2014-10-31 公開日 2015-04-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography. J.Am.Chem.Soc., 137, 2015
5V5H	OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.2 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, RNA-directed RNA polymerase L, SODIUM ION, ... 著者 Khare, B, Mark, B.L. 登録日 2017-03-14 公開日 2017-05-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathog., 13, 2017
5V5G	OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.4 分子名称: 1,2-ETHANEDIOL, RNA-directed RNA polymerase L, SODIUM ION, ... 著者 Khare, B, Mark, B.L. 登録日 2017-03-14 公開日 2017-05-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathog., 13, 2017
6YWO	CutA in complex with A3 RNA 分子名称: CHLORIDE ION, CutA, MAGNESIUM ION, ... 著者 Malik, D, Kobylecki, K, Krawczyk, P, Poznanski, J, Jakielaszek, A, Napiorkowska, A, Dziembowski, A, Tomecki, R, Nowotny, M. 登録日 2020-04-29 公開日 2020-08-05 最終更新日 2020-09-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine. Nucleic Acids Res., 48, 2020
9ICT	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DGTP AND MNCL2 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-16 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICQ	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-01-04 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICF	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND ZNCL2 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*GP*A)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-15 公開日 1995-12-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICU	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DTTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), MANGANESE (II) ION, ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-16 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICV	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND ZNCL2 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*GP*A)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-16 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICR	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DCTP AND MNCL2 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-01-04 公開日 1996-01-04 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICO	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF DTTP AND MGCL2 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-16 公開日 1995-12-16 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICS	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2',3'-DIDEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DDCTP AND MNCL2 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-16 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICP	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF PYROPHOSPHATE (1 MILLIMOLAR) AND MGCL2 (5 MILLIMOLAR) 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-16 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICN	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2',3'-DIDEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DDCTP AND MGCL2 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-16 公開日 1995-12-16 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICK	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ARTIFICIAL MOTHER LIQUOR 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-16 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
5IF2	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-576 (5,6-dichloro-1H-1,3-benzodiazol-2-yl)methanol 分子名称: (5,6-dichloro-1H-benzimidazol-2-yl)methanol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published

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