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1W14
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UROKINASE TYPE PLASMINOGEN ACTIVATOR
分子名称: N-[(2-PHENYLETHYL)SULFONYL]-D-SERYL-N-[(1S)-4-[(DIAMINOMETHYLENE)AMINO]-1-(HYDROXYMETHYL)BUTYL]-L-ALANINAMIDE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR
著者Jacob, U.
登録日2004-06-15
公開日2008-05-20
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystals of Urokinase Type Plasminogen Activator Complexes Reveal the Binding Mode of Peptidomimetic Inhibitors.
J.Mol.Biol., 328, 2003
8T8T
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Crystal structure of TET25 in complex with PyDH2 ligand in P212121 space group
分子名称: 4,4'-{pyridine-2,6-diylbis[carbonyl-(1E)-hydrazin-2-yl-1-ylidene-(E)-methanylylidene]}bis(1-methylquinolin-1-ium), POTASSIUM ION, TET25
著者Lam, G, Yatsunyk, L.A.
登録日2023-06-23
公開日2024-09-04
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystal structure of TET25 in complex with PyDH2 ligand in P212121 space group
To be Published
3S9L
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Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ...
著者Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J.
登録日2011-06-01
公開日2011-08-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.
Proc.Natl.Acad.Sci.USA, 108, 2011
2BIV
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Crystal structure of the wild-type MBT domains of Human SCML2
分子名称: IODIDE ION, SEX COMB ON MIDLEG-LIKE PROTEIN 2, SODIUM ION
著者Santiveri, C.M, Allen, M.D, Sait, F, Bycroft, M.
登録日2005-01-26
公開日2005-02-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Malignant Brain Tumor Repeats of Human Scml2 Bind to Peptides Containing Monomethylated Lysine.
J.Mol.Biol., 382, 2008
1YKJ
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A45G p-hydroxybenzoate hydroxylase with p-hydroxybenzoate bound
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, P-hydroxybenzoate hydroxylase, ...
著者Cole, L.J, Gatti, D.L, Entsch, B, Ballou, D.P.
登録日2005-01-18
公開日2005-07-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Removal of a methyl group causes global changes in p-hydroxybenzoate hydroxylase.
Biochemistry, 44, 2005
1YI2
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BU of 1yi2 by Molmil
Crystal Structure Of Erythromycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui
分子名称: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-11
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
1YHQ
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Crystal Structure Of Azithromycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui
分子名称: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-10
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
1DUQ
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CRYSTAL STRUCTURE OF THE REV BINDING ELEMENT OF HIV-1
分子名称: SODIUM ION, THE REV BINDING ELEMENT
著者Hung, L.-W, Holbrook, E.L, Holbrook, S.R.
登録日2000-01-18
公開日2000-05-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of the Rev binding element of HIV-1 reveals novel base pairing and conformational variability.
Proc.Natl.Acad.Sci.USA, 97, 2000
1YIT
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Crystal Structure Of Virginiamycin M and S Bound To The 50S Ribosomal Subunit Of Haloarcula Marismortui
分子名称: 23S RIBOSOMAL RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-13
公開日2005-04-26
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance.
Cell(Cambridge,Mass.), 121, 2005
3CR6
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Crystal Structure of the R132K:R111L:A32E Mutant of Cellular Retinoic Acid Binding Protein Type II Complexed with C15-aldehyde (a retinal analog) at 1.22 Angstrom resolution.
分子名称: 1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene, Cellular retinoic acid-binding protein 2
著者Jia, X, Geiger, J.H.
登録日2008-04-04
公開日2009-03-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Two distinctive orientations of binding determined by a single mutation in the CRABPII mutant-C15-aldehyde complexes
To be Published
2CE8
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An EH1 peptide bound to the Groucho-TLE WD40 domain.
分子名称: EH1 PEPTIDE, TRANSDUCIN-LIKE ENHANCER PROTEIN 1
著者Pickles, L.M, Roe, S.M, Pearl, L.H.
登録日2006-02-03
公開日2006-06-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular Recognition of Transcriptional Repressor Motifs by the Wd Domain of the Groucho/Tle Corepressor.
Mol.Cell, 22, 2006
1W7F
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BU of 1w7f by Molmil
Crystal structure of the class A beta-lactamase BS3 inhibited with isocitrate
分子名称: BETA-LACTAMASE, ISOCITRIC ACID
著者Petrella, S, Sauvage, E, Herman, R, Charlier, P.
登録日2004-09-01
公開日2006-05-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Class a Beta-Lactamase Bs3 Bs3 Inhibited with Isocitrate
To be Published
3D8C
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BU of 3d8c by Molmil
Factor inhibiting HIF-1 alpha D201G mutant in complex with ZN(II), alpha-ketoglutarate and HIF-1 alpha 19mer
分子名称: 2-OXOGLUTARIC ACID, GLYCEROL, HYPOXIA-INDUCIBLE FACTOR 1 ALPHA, ...
著者McDonough, M.A, Chowdhury, R, Schofield, C.J.
登録日2008-05-23
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Evidence that two enzyme-derived histidine ligands are sufficient for iron binding and catalysis by factor inhibiting HIF (FIH).
J.Biol.Chem., 283, 2008
2MV7
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BU of 2mv7 by Molmil
Solution NMR structure of DOT1L in complex with AF9 (DOT1L-AF9)
分子名称: Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-9
著者Kuntimaddi, A, Bushweller, J.H.
登録日2014-09-24
公開日2015-04-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential.
Cell Rep, 11, 2015
2MUK
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BU of 2muk by Molmil
1H, 13C, and 15N Chemical Shift Assignments for AUX/IAA17
分子名称: Auxin-responsive protein IAA17
著者Suh, J, Han, M.
登録日2014-09-11
公開日2014-12-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for the auxin-induced transcriptional regulation by Aux/IAA17.
Proc.Natl.Acad.Sci.USA, 111, 2014
3D96
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Crystal Structure of the R132K:Y134F Mutant of Apo-Cellular Retinoic Acid Binding Protein Type II at 1.71 Angstroms Resolution
分子名称: ACETATE ION, Cellular retinoic acid-binding protein 2
著者Vaezeslami, S, Geiger, J.H.
登録日2008-05-26
公開日2008-07-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structural analysis of site-directed mutants of cellular retinoic acid-binding protein II addresses the relationship between structural integrity and ligand binding.
Acta Crystallogr.,Sect.D, 64, 2008
1CSL
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BU of 1csl by Molmil
CRYSTAL STRUCTURE OF THE RRE HIGH AFFINITY SITE
分子名称: 5'-R(*AP*AP*CP*GP*GP*GP*CP*GP*CP*AP*GP*AP*A)-3', 5'-R(*UP*CP*UP*GP*AP*CP*GP*GP*UP*AP*CP*GP*UP*UP*U)-3'
著者Ippolito, J.A, Steitz, T.A.
登録日1999-08-18
公開日2000-02-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structure of the HIV-1 RRE high affinity rev binding site at 1.6 A resolution.
J.Mol.Biol., 295, 2000
2CMN
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BU of 2cmn by Molmil
A Proximal Arginine Residue in the Switching Mechanism of the FixL Oxygen Sensor
分子名称: PROTOPORPHYRIN IX CONTAINING FE, SENSOR PROTEIN FIXL
著者Gilles-Gonzalez, M.-A, Caceres, A.I, Silva Sousa, E.H, Tomchick, D.R, Brautigam, C.A, Gonzalez, C, Machius, M.
登録日2006-05-11
公開日2007-05-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Proximal Arginine R206 Participates in Switching of the Bradyrhizobium Japonicum Fixl Oxygen Sensor
J.Mol.Biol., 360, 2006
3DDK
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Coxsackievirus B3 3Dpol RNA Dependent RNA Polymerase
分子名称: RNA polymerase B3 3Dpol, SODIUM ION, SULFATE ION
著者Campagnola, G, Weygandt, M.H, Scoggin, K.E, Peersen, O.B.
登録日2008-06-05
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of Coxsackievirus B3 3Dpol Highlights Functional Importance of Residue 5 in Picornaviral Polymerases
J.Virol., 82, 2008
3DAI
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BU of 3dai by Molmil
Crystal structure of the bromodomain of the human ATAD2
分子名称: ATPase family AAA domain-containing protein 2, CHLORIDE ION, SULFATE ION
著者Filippakopoulos, P, Keates, T, Picaud, S, Fedorov, O, Roos, A.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2008-05-29
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
1VQ6
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The structure of c-hpmn and CCA-PHE-CAP-BIO bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*(5AA)*(HFA))-3', 5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3', ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.
Nature, 438, 2005
2C1N
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Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3
分子名称: 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE
著者Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C.
登録日2005-09-16
公開日2005-11-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
Mol.Cell, 20, 2005
3T6O
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The Structure of an Anti-sigma-factor antagonist (STAS) domain protein from Planctomyces limnophilus.
分子名称: CHLORIDE ION, Sulfate transporter/antisigma-factor antagonist STAS
著者Cuff, M.E, Moser, C, Hatzos-Skintges, C, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2011-07-28
公開日2011-09-07
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Structure of an Anti-sigma-factor antagonist (STAS) domain protein from Planctomyces limnophilus.
TO BE PUBLISHED
1VQ5
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The structure of the transition state analogue "RAA" bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-D(*(DC)P*(DC)P*(5AA)P*(2OP)P*(PO2)P*AP*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
5EIZ
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Crystal structure of Y99A mutant of human macrophage migration inhibitory factor
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
著者Pantouris, G, Lolis, E.
登録日2015-10-30
公開日2015-11-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.
Angew. Chem. Int. Ed. Engl., 2018

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件を2024-09-18に公開中

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