PDB: 1955 件ウェブページステータス検索Chemie searchBIRD

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7VW5	Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold 分子名称: MAGNESIUM ION, RNA-directed RNA polymerase nsP4 著者 Tan, Y.B, Luo, D. 登録日 2021-11-09 公開日 2022-02-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold. Nucleic Acids Res., 50, 2022
7VMV	Crystal structure of Dengue NS2B-NS3 Protease after secondary cleavage 分子名称: Core protein 著者 Quek, J.P. 登録日 2021-10-09 公開日 2022-07-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.351 Å) 主引用文献 Dynamic Interactions of Post Cleaved NS2B Cofactor and NS3 Protease Identified by Integrative Structural Approaches. Viruses, 14, 2022
7VH3	Cryo-EM structure of Machupo virus polymerase L 分子名称: RNA-directed RNA polymerase L 著者 Ma, J, Zhang, S, Zhang, X. 登録日 2021-09-20 公開日 2021-09-29 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
7VH1	Cryo-EM structure of Machupo virus dimeric L-Z complex 分子名称: Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z, RNA-directed RNA polymerase L, ZINC ION 著者 Zhang, X, Ma, J, Zhang, S. 登録日 2021-09-20 公開日 2021-09-29 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
7VH2	Cryo-EM structure of Machupo virus dimeric polymerase L 分子名称: RNA-directed RNA polymerase L 著者 Zhang, X, Ma, J, Zhang, S. 登録日 2021-09-20 公開日 2021-09-29 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
7VGQ	Cryo-EM structure of Machupo virus polymerase L in complex with matrix protein Z 分子名称: Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z, RNA-directed RNA polymerase L, ZINC ION 著者 Zhang, X, Ma, J, Zhang, S. 登録日 2021-09-18 公開日 2021-09-29 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
7PLR	Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound Baloxavir 分子名称: Baloxavir acid, FORMIC ACID, GLYCEROL, ... 著者 Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K. 登録日 2021-09-01 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound Baloxavir To Be Published
7VB4	A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically dynamic RNA-dependent RNA polymerase 分子名称: GLYCEROL, MAGNESIUM ION, RNA-directed RNA polymerase nsP4 著者 Tan, Y.B, Luo, D. 登録日 2021-08-30 公開日 2022-02-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold. Nucleic Acids Res., 50, 2022
7V99	catalytic core of human telomerase holoenzyme 分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Primer DNA, ... 著者 Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M. 登録日 2021-08-24 公開日 2022-03-30 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Zipper head mechanism of telomere synthesis by human telomerase. Cell Res., 31, 2021
7V2Z	ZIKV NS3helicase in complex with ssRNA and ATP-Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Core protein, MANGANESE (II) ION, ... 著者 Lin, M.M, Yang, H.T. 登録日 2021-08-10 公開日 2022-08-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.10101676 Å) 主引用文献 Structural Basis of Zika Virus Helicase in RNA Unwinding and ATP Hydrolysis. Acs Infect Dis., 8, 2022
7RQS	Arabidopsis RNA-dependent RNA polymerase 2 分子名称: MAGNESIUM ION, RNA-dependent RNA polymerase 2 著者 Fukudome, A, Pikaard, C.S, Takagi, Y. 登録日 2021-08-07 公開日 2021-12-08 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 Structure and RNA template requirements of Arabidopsis RNA-DEPENDENT RNA POLYMERASE 2. Proc.Natl.Acad.Sci.USA, 118, 2021
7V1G	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (with a GMP-Arg28 adduct and in complex with SAM) 分子名称: CITRIC ACID, Core protein, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1B	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH) 分子名称: CITRIC ACID, Core protein, ISOPROPYL ALCOHOL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1F	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM and GTP) 分子名称: Core protein, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1C	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SIN) 分子名称: Core protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1H	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM and m7GTP) 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CITRIC ACID, Core protein, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1E	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and m7GpppAmG) 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, Core protein, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1I	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (with an m7GMP-Arg28 adduct and in complex with SAH) 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Core protein, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1D	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and GpppA) 分子名称: Core protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1J	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and m7GpppA) 分子名称: Core protein, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7FJT	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM) 分子名称: CITRIC ACID, Core protein, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7ROZ	Structure of RNA-dependent RNA polymerase 2 (RDR2) from Arabidopsis thaliana 分子名称: MAGNESIUM ION, RNA-dependent RNA polymerase 2 著者 Fukudome, A, Pikaard, C.S, Takagi, Y. 登録日 2021-08-02 公開日 2021-12-08 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure and RNA template requirements of Arabidopsis RNA-DEPENDENT RNA POLYMERASE 2. Proc.Natl.Acad.Sci.USA, 118, 2021
7RKP	The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with cyclic compound SJ001034733 分子名称: (5R)-5-hydroxy-16,21-dioxa-3,8,28-triazatetracyclo[20.3.1.1~2,6~.1~11,15~]octacosa-1(26),2,6(28),11(27),12,14,22,24-octaene-4,7-dione, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2021-07-22 公開日 2022-07-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
7RIQ	RNA polymerase II elongation complex scaffold 1 without polyamide 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Oh, J, Dervan, P.B, Wang, D. 登録日 2021-07-20 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proc.Natl.Acad.Sci.USA, 119, 2022
7RIY	RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2 soaked with UTP 分子名称: 3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[(1-methyl-4-{[1-methyl-4-({1-methyl-4-[(1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-carbonyl)amino]butanoyl}amino)-1-methyl-1H-imidazole-2-carbonyl]amino}-1-methyl-1H-pyrrole-2-carbonyl)amino]-1-methyl-1H-pyrrole-2-carbonyl}amino)-1-methyl-1H-pyrrole-2-carbonyl]amino}propyl)(methyl)amino]propyl}carbamoyl)benzoic acid, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Oh, J, Dervan, P.B, Wang, D. 登録日 2021-07-20 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proc.Natl.Acad.Sci.USA, 119, 2022

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