7H0K
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![BU of 7h0k by Molmil](/molmil-images/mine/7h0k) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0011076-001 | 分子名称: | 4-{[(1S)-1-(1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~,2-benzothiazin-7-yl)-2-methylpropyl]amino}-N-ethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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7SC7
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![BU of 7sc7 by Molmil](/molmil-images/mine/7sc7) | Synechocystis PCC 6803 Phycobilisome core from up-down rod conformation | 分子名称: | Allophycocyanin alpha chain, Allophycocyanin beta chain, Allophycocyanin subunit alpha-B, ... | 著者 | Sauer, P.V, Sutter, M, Dominguez-Martin, M.A, Kirst, H, Kerfeld, C.A. | 登録日 | 2021-09-27 | 公開日 | 2022-08-31 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structures of a phycobilisome in light-harvesting and photoprotected states. Nature, 609, 2022
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8OMG
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![BU of 8omg by Molmil](/molmil-images/mine/8omg) | Crystal structure of mKHK (apo) | 分子名称: | Ketohexokinase | 著者 | Ebenhoch, E, Pautsch, P. | 登録日 | 2023-03-31 | 公開日 | 2023-09-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design. Acta Crystallogr D Struct Biol, 79, 2023
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3GQT
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![BU of 3gqt by Molmil](/molmil-images/mine/3gqt) | Crystal structure of glutaryl-CoA dehydrogenase from Burkholderia pseudomallei with fragment (1,4-dimethyl-1,2,3,4-tetrahydroquinoxalin-6-yl)methylamine | 分子名称: | 1-(1,4-dimethyl-1,2,3,4-tetrahydroquinoxalin-6-yl)methanamine, Glutaryl-CoA dehydrogenase | 著者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2009-03-24 | 公開日 | 2009-04-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening. Acta Crystallogr.,Sect.F, 67, 2011
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7SC9
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![BU of 7sc9 by Molmil](/molmil-images/mine/7sc9) | Synechocystis PCC 6803 Phycobilisome core, complex with OCP | 分子名称: | Allophycocyanin alpha chain, Allophycocyanin beta chain, Allophycocyanin subunit alpha-B, ... | 著者 | Sauer, P.V, Sutter, M, Dominguez-Martin, M.A, Kirst, H, Kerfeld, C.A. | 登録日 | 2021-09-27 | 公開日 | 2022-08-31 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structures of a phycobilisome in light-harvesting and photoprotected states. Nature, 609, 2022
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2HMX
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![BU of 2hmx by Molmil](/molmil-images/mine/2hmx) | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 MATRIX PROTEIN | 分子名称: | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 MATRIX PROTEIN | 著者 | Massiah, M.A, Starich, M.R, Paschall, C, Christensen, A.M, Sundquist, W.I, Summers, M.F. | 登録日 | 1995-09-22 | 公開日 | 1996-01-29 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure of the human immunodeficiency virus type 1 matrix protein. J.Mol.Biol., 244, 1994
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7A9E
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![BU of 7a9e by Molmil](/molmil-images/mine/7a9e) | tRNA-guanine transglycosylase C158S/C281S/Y330C/H333A mutant in complex with ethyl methyl sulfone | 分子名称: | 1,2-ETHANEDIOL, 1-methylsulfonylethane, GLYCEROL, ... | 著者 | Nguyen, D, You, S, Heine, A, Klebe, G. | 登録日 | 2020-09-01 | 公開日 | 2021-06-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface. Acs Chem.Biol., 16, 2021
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5JXG
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![BU of 5jxg by Molmil](/molmil-images/mine/5jxg) | Structure of the unliganded form of the proprotein convertase furin. | 分子名称: | CALCIUM ION, CHLORIDE ION, Furin, ... | 著者 | Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E. | 登録日 | 2016-05-13 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
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7S01
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![BU of 7s01 by Molmil](/molmil-images/mine/7s01) | X-ray structure of the phage AR9 non-virion RNA polymerase holoenzyme in complex with a forked oligonucleotide containing the P077 promoter | 分子名称: | DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ... | 著者 | Leiman, P.G, Sokolova, M.L, Gordeeva, J, Fraser, A, Severinov, K.V. | 登録日 | 2021-08-28 | 公開日 | 2022-07-06 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
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8P24
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2YCJ
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![BU of 2ycj by Molmil](/molmil-images/mine/2ycj) | methyltransferase bound with methyltetrahydrofolate | 分子名称: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-METHYLTETRAHYDROFOLATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE, GLYCEROL, ... | 著者 | Goetzl, S, Jeoung, J.-H, Hennig, S.E, Dobbek, H. | 登録日 | 2011-03-16 | 公開日 | 2011-06-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural Basis for Electron and Methyl-Group Transfer in a Methyltransferase System Operating in the Reductive Acetyl-Coa Pathway J.Mol.Biol., 411, 2011
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3GVL
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![BU of 3gvl by Molmil](/molmil-images/mine/3gvl) | Crystal Structure of endo-neuraminidaseNF | 分子名称: | Endo-N-acetylneuraminidase, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid, N-acetyl-beta-neuraminic acid | 著者 | Schulz, E.C, Dickmanns, A, Ficner, R. | 登録日 | 2009-03-31 | 公開日 | 2010-03-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Structural basis for the recognition and cleavage of polysialic acid by the bacteriophage K1F tailspike protein EndoNF. J.Mol.Biol., 397, 2010
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5JZQ
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![BU of 5jzq by Molmil](/molmil-images/mine/5jzq) | |
2HHB
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![BU of 2hhb by Molmil](/molmil-images/mine/2hhb) | |
7D6L
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![BU of 7d6l by Molmil](/molmil-images/mine/7d6l) | |
5JZY
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![BU of 5jzy by Molmil](/molmil-images/mine/5jzy) | Thrombin in complex with (S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(4-carbamimidoylbenzyl)pyrrolidine-2-carboxamide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-cyclohexyl-D-alanyl-N-[(4-carbamimidoylphenyl)methyl]-L-prolinamide, DIMETHYL SULFOXIDE, ... | 著者 | Sandner, A, Heine, A, Klebe, G. | 登録日 | 2016-05-17 | 公開日 | 2017-06-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | Strategies for Late-Stage Optimization: Profiling Thermodynamics by Preorganization and Salt Bridge Shielding. J.Med.Chem., 62, 2019
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8OYL
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![BU of 8oyl by Molmil](/molmil-images/mine/8oyl) | Coiled-Coil Domain of Human STIL, Q729L Mutant | 分子名称: | CADMIUM ION, CHLORIDE ION, SCL-interrupting locus protein, ... | 著者 | Martin, F.J.O, Shamir, M, Woolfson, D.N, Friedler, A. | 登録日 | 2023-05-05 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Molecular Mechanism of STIL Coiled-Coil Domain Oligomerization. Int J Mol Sci, 24, 2023
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2Y9X
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![BU of 2y9x by Molmil](/molmil-images/mine/2y9x) | Crystal structure of PPO3, a tyrosinase from Agaricus bisporus, in deoxy-form that contains additional unknown lectin-like subunit, with inhibitor tropolone | 分子名称: | 2-HYDROXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE, COPPER (II) ION, HOLMIUM ATOM, ... | 著者 | Ismaya, W.T, Rozeboom, H.J, Weijn, A, Mes, J.J, Fusetti, F, Wichers, H.J, Dijkstra, B.W. | 登録日 | 2011-02-17 | 公開日 | 2011-07-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Crystal Structure of Agaricus Bisporus Mushroom Tyrosinase: Identity of the Tetramer Subunits and Interaction with Tropolone. Biochemistry, 50, 2011
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7SDN
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![BU of 7sdn by Molmil](/molmil-images/mine/7sdn) | [C:Ag+:U] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*UP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (4.32 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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8P10
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2YUX
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![BU of 2yux by Molmil](/molmil-images/mine/2yux) | Solution Structure of 3rd Fibronectin type three Domain of slow type Myosin-Binding Protein C | 分子名称: | Myosin-binding protein C, slow-type | 著者 | Niraula, T.N, Tochio, N, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-06 | 公開日 | 2008-04-08 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of 3rd Fibronectin type three Domain of slow type Myosin-Binding Protein C To be Published
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7SDT
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![BU of 7sdt by Molmil](/molmil-images/mine/7sdt) | [iU:Ag+:S] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*(5IU)P*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*(IMC)P*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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7A3F
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![BU of 7a3f by Molmil](/molmil-images/mine/7a3f) | Crystal structure of apo DPP9 | 分子名称: | Dipeptidyl peptidase 9, GLYCEROL, PHOSPHATE ION | 著者 | Ross, B.H, Huber, R. | 登録日 | 2020-08-18 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Discovery and Development of 4-Oxo-beta-Lactams as Novel Inhibitors of Dipeptidyl Peptidases 8 and 9 To Be Published
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7DNJ
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![BU of 7dnj by Molmil](/molmil-images/mine/7dnj) | K63-polyUb MDA5CARDs complex | 分子名称: | Interferon-induced helicase C domain-containing protein 1, Ubiquitin | 著者 | Song, B, Chen, Y, Luo, D.H, Zheng, J. | 登録日 | 2020-12-09 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains. Immunity, 54, 2021
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7H00
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![BU of 7h00 by Molmil](/molmil-images/mine/7h00) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0011221-001 | 分子名称: | (4M)-4-(4-{[(1S)-1-(2,3-dihydro[1,4]dioxino[2,3-b]pyridin-6-yl)-2,2-dimethylpropyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-1-methyl-1H-pyrazole-5-carbonitrile, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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