PDB: 3116 件ウェブページステータス検索Chemie searchBIRD

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6ZQF	Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-B (Poly-Ala) 分子名称: 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... 著者 Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. 登録日 2020-07-09 公開日 2020-09-23 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
7AJT	Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... 著者 Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. 登録日 2020-09-29 公開日 2020-12-30 最終更新日 2021-02-03 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome. Mol.Cell, 81, 2021
7AKY	Crystal structure of the viral rhodopsin OLPVR1 in P21212 space group 分子名称: (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, EICOSANE, viral rhodopsin OLPVR1 著者 Kovalev, K, Zabelskii, D, Alekseev, A, Astashkin, R, Gordeliy, V. 登録日 2020-10-02 公開日 2020-11-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Viral rhodopsins 1 are an unique family of light-gated cation channels. Nat Commun, 11, 2020
5IBF	Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 19a 分子名称: 4-(3'-amino[1,1'-biphenyl]-3-yl)-1H-pyrazol-5-amine, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Levy, C. 登録日 2016-02-22 公開日 2016-04-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors. J.Med.Chem., 59, 2016
7NQO	Mycobacterium tuberculosis Cytochrome P450 CYP121 in complex with lead compound 21 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[4-[2-(5-bromanyl-1~{H}-indol-3-yl)ethyl]pyrimidin-2-yl]morpholine, CHLORIDE ION, ... 著者 Selvam, I.R. 登録日 2021-03-01 公開日 2022-02-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen). Eur.J.Med.Chem., 230, 2022
6PSV	Escherichia coli RNA polymerase promoter unwinding intermediate (TpreRPo) with TraR and rpsT P2 promoter 分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2019-07-13 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6PST	Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5b) with TraR and mutant rpsT P2 promoter 分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2019-07-13 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
7AVN	Structure of marine actinobacteria clade rhodopsin (MacR) in orange form in P1 space group 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Bacteriorhodopsin, ... 著者 Gushchin, I, Polovinkin, V, Kovalev, K, Shevchenko, V, Gordeliy, V. 登録日 2020-11-05 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Alternating Access Mechanism in a Minimalistic Light-Driven Proton Pump To Be Published
7AVP	Structure of marine actinobacteria clade rhodopsin (MacR) in violet form 分子名称: Bacteriorhodopsin, EICOSANE 著者 Gushchin, I, Polovinkin, V, Kovalev, K, Shevchenko, V, Gordeliy, V. 登録日 2020-11-05 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Alternating Access Mechanism in a Minimalistic Light-Driven Proton Pump To Be Published
7AVO	Structure of marine actinobacteria clade rhodopsin (MacR) in orange form in P1211 space group 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Bacteriorhodopsin, ... 著者 Gushchin, I, Polovinkin, V, Kovalev, K, Shevchenko, V, Gordeliy, V. 登録日 2020-11-05 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Alternating Access Mechanism in a Minimalistic Light-Driven Proton Pump To Be Published
5JYK	Deg9 crystal under 289K 分子名称: GLYCEROL, Protease Do-like 9 著者 Ouyang, M, Zhang, L.X. 登録日 2016-05-14 公開日 2017-05-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.297 Å) 主引用文献 The crystal structure of Deg9 reveals a novel octameric-type HtrA protease Nat Plants, 3, 2017
4IPS	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazin-2-one, Cytochrome P450 121, GLYCEROL, ... 著者 Fonvielle, M, LeDu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-10 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
4IPW	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3-(3,4-dihydroxybenzyl)-6-(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, GLYCEROL, ... 著者 Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-10 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
4IQ7	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3-(4-hydroxybenzyl)-6-methylpiperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-11 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
4IQ9	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3-(4-hydroxybenzyl)-6-(1H-indol-3-ylmethyl)piperazine-2,5-dione, Cytochrome P450 121, GLYCEROL, ... 著者 Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-11 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
7BMH	Crystal structure of a light-driven proton pump LR (Mac) from Leptosphaeria maculans 分子名称: EICOSANE, OLEIC ACID, Opsin 著者 Kovalev, K, Zabelskii, D, Dmitrieva, N, Volkov, O, Shevchenko, V, Astashkin, R, Zinovev, E, Gordeliy, V. 登録日 2021-01-20 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-based insights into evolution of rhodopsins. Commun Biol, 4, 2021
7FDN	Crystal structure of transcription factor WER in complex with EGL3 分子名称: CHLORIDE ION, GLYCEROL, SODIUM ION, ... 著者 Luo, Q, Wang, B. 登録日 2021-07-17 公開日 2022-07-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into partner selection for MYB and bHLH transcription factor complexes. Nat.Plants, 8, 2021
7FDM	Crystal structure of transcription factor MYB29 in complex with MYC3 分子名称: Transcription factor MYB29, Transcription factor MYC3 著者 Luo, Q, Wang, B. 登録日 2021-07-17 公開日 2022-07-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insights into partner selection for MYB and bHLH transcription factor complexes. Nat.Plants, 8, 2021
7FDL	Crystal structure of transcription factor WER in complex with EGL3 分子名称: Transcription factor EGL1, Transcription factor WER 著者 Luo, Q, Wang, B. 登録日 2021-07-17 公開日 2022-07-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.897 Å) 主引用文献 Structural insights into partner selection for MYB and bHLH transcription factor complexes. Nat.Plants, 8, 2021
4G47	Structure of cytochrome P450 CYP121 in complex with 4-(1H-1,2,4-triazol-1-yl)phenol 分子名称: 4-(1H-1,2,4-triazol-1-yl)phenol, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Hudson, S.A, McLean, K.J, Surade, S, Yang, Y.-Q, Leys, D, Ciulli, A, Munro, A.W, Abell, C. 登録日 2012-07-16 公開日 2012-09-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121 Angew.Chem.Int.Ed.Engl., 51, 2012
4G44	Structure of P450 CYP121 in complex with lead compound MB286, 3-((1H-1,2,4-triazol-1-yl)methyl)aniline 分子名称: 3-(1H-1,2,4-triazol-1-ylmethyl)aniline, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Hudson, S.A, McLean, K.J, Surade, S, Yang, Y.-Q, Leys, D, Ciulli, A, Munro, A.W, Abell, C. 登録日 2012-07-16 公開日 2012-09-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121 Angew.Chem.Int.Ed.Engl., 51, 2012
4G45	Structure of cytochrome CYP121 in complex with 2-methylquinolin-6-amine 分子名称: 2-methylquinolin-6-amine, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Hudson, S.A, McLean, K.J, Surade, S, Yang, Y.-Q, Leys, D, Ciulli, A, Munro, A.W, Abell, C. 登録日 2012-07-16 公開日 2012-09-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121 Angew.Chem.Int.Ed.Engl., 51, 2012
4G46	Structure of cytochrome P450 CYP121 in complex with 4-oxo-4,5,6,7-tetrahydrobenzofuran-3-carboxylate 分子名称: 4-oxo-4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Hudson, S.A, McLean, K.J, Surade, S, Yang, Y.-Q, Leys, D, Ciulli, A, Munro, A.W, Abell, C. 登録日 2012-07-16 公開日 2012-09-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121 Angew.Chem.Int.Ed.Engl., 51, 2012
4G1X	Crystal structure of Mycobacterium tuberculosis CYP121 in complex with 4-(1H-1,2,4-triazol-1-yl)quinolin-6-amine 分子名称: 4-(1H-1,2,4-triazol-1-yl)quinolin-6-amine, Cytochrome P450 121, DIMETHYL SULFOXIDE, ... 著者 Hudson, S.A. 登録日 2012-07-11 公開日 2012-09-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121 Angew.Chem.Int.Ed.Engl., 51, 2012
4G48	Structure of CYP121 in complex with 4-(4-phenoxy-1H-pyrazol-3-yl)benzene-1,3-diol 分子名称: 4-(4-phenoxy-1H-pyrazol-3-yl)benzene-1,3-diol, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Hudson, S.A, McLean, K.J, Surade, S, Yang, Y.-Q, Leys, D, Ciulli, A, Munro, A.W, Abell, C. 登録日 2012-07-16 公開日 2012-09-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121 Angew.Chem.Int.Ed.Engl., 51, 2012

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