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3WHK
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Crystal structure of PAN-Rpt5C chimera
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Proteasome-activating nucleotidase, 26S protease regulatory subunit 6A
著者Satoh, T, Saeki, Y, Hiromoto, T, Wang, Y.-H, Uekusa, Y, Yagi, H, Yoshihara, H, Yagi-Utsumi, M, Mizushima, T, Tanaka, K, Kato, K.
登録日2013-08-26
公開日2014-03-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for proteasome formation controlled by an assembly chaperone nas2.
Structure, 22, 2014
3WD4
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Serratia marcescens Chitinase B complexed with azide inhibitor and quinoline compound
分子名称: (E)-N-(prop-2-en-1-yloxy)-1-(quinolin-4-yl)methanimine, Chitinase B, GLYCEROL, ...
著者Hirose, T, Maita, N, Gouda, H, Koseki, J, Yamamoto, T, Sugawara, A, Nakano, H, Hirono, S, Shiomi, K, Watanabe, T, Taniguchi, H, Sharpless, K.B, Omura, S, Sunazuka, T.
登録日2013-06-06
公開日2013-09-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
Proc.Natl.Acad.Sci.USA, 110, 2013
2C8O
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BU of 2c8o by Molmil
lysozyme (1sec) and UV lasr excited fluorescence
分子名称: LYSOZYME C
著者Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D.
登録日2005-12-06
公開日2006-03-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops.
Acta Crystallogr.,Sect.D, 62, 2006
5UKW
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BU of 5ukw by Molmil
Crystal structure of human Glucose 6-phosphate Dehydrogenase mutant (A277C) complexed with G6P
分子名称: 6-O-phosphono-beta-D-glucopyranose, GLYCEROL, Glucose-6-phosphate 1-dehydrogenase
著者Ranzani, A.T, Cordeiro, A.T.
登録日2017-01-23
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Mutations in the tetramer interface of human glucose-6-phosphate dehydrogenase reveals kinetic differences between oligomeric states.
FEBS Lett., 591, 2017
5CNV
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BU of 5cnv by Molmil
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to GDP and TTP at 3.20 Angstroms resolution
分子名称: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L.
登録日2015-07-18
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli.
Elife, 5, 2016
5ULX
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BU of 5ulx by Molmil
Structure of human DNA polymerase iota bound to template 1-methyl-deoxyadenosine crystallized in the presence of dCTP
分子名称: CHLORIDE ION, DNA (5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3'), DNA (5'-D(P*(MA7)P*GP*GP*GP*TP*CP*CP*T)-3'), ...
著者Jain, R, Aggarwal, A.K.
登録日2017-01-25
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-iota.
Sci Rep, 7, 2017
3WKE
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BU of 3wke by Molmil
Crystal structure of soluble epoxide hydrolase in complex with t-AUCB
分子名称: 4-[(trans-4-{[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]dec-1-ylcarbamoyl]amino}cyclohexyl)oxy]benzoic acid, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ...
著者Amano, Y, Yamaguchi, T, Tanabe, E.
登録日2013-10-18
公開日2014-04-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography.
Bioorg.Med.Chem., 22, 2014
1ZOF
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BU of 1zof by Molmil
Crystal structure of alkyl hydroperoxide-reductase (AhpC) from Helicobacter Pylori
分子名称: alkyl hydroperoxide-reductase
著者Papinutto, E, Windle, H.J, Cendron, L, Battistutta, R, Kelleher, D, Zanotti, G.
登録日2005-05-13
公開日2005-11-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of alkyl hydroperoxide-reductase (AhpC) from Helicobacter pylori.
Biochim.Biophys.Acta, 1753, 2005
5BXV
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eIF4E complex
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1
著者Sekiyama, N, Arthanari, H, Papdopoulos, E, Rodriguez-Mias, R.A, Wagner, G, Leger-Abraham, M.
登録日2015-06-09
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.
Proc.Natl.Acad.Sci.USA, 112, 2015
5UJ9
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BU of 5uj9 by Molmil
Cryo-EM structure of bovine multidrug resistance protein 1 (MRP1)
分子名称: bovine multidrug resistance protein 1 (MRP1),Multidrug resistance-associated protein 1
著者Johnson, Z.L, Chen, J.
登録日2017-01-17
公開日2017-02-22
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Structural Basis of Substrate Recognition by the Multidrug Resistance Protein MRP1.
Cell, 168, 2017
2C9I
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BU of 2c9i by Molmil
Structure of the fluorescent protein asFP499 from Anemonia sulcata
分子名称: GREEN FLUORESCENT PROTEIN ASFP499
著者Renzi, F, Nienhaus, K, Wiedenmann, J, Vallone, B, Nienhaus, G.U.
登録日2005-12-12
公開日2007-01-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Chromophore-Protein Interactions in the Anthozoan Green Fluorescent Protein Asfp499
Biophys.J., 91, 2006
5UKN
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BU of 5ukn by Molmil
Structure of unliganded anti-gp120 CD4bs antibody DH522UCA Fab
分子名称: CHLORIDE ION, DH522UCA Fab fragment heavy chain, DH522UCA Fab fragment light chain
著者Nicely, N.I.
登録日2017-01-23
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.
Nat Commun, 8, 2017
3WIJ
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BU of 3wij by Molmil
Crystal structure of a plant class V chitinase mutant from Cycas revoluta in complex with (GlcNAc)3
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Numata, T, Osawa, T, Umemoto, N, Ohnuma, T, Fukamizo, T.
登録日2013-09-13
公開日2014-09-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of a plant class V chitinase mutant from Cycas revoluta in complex with (GlcNAc)3
To be Published
5UKP
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BU of 5ukp by Molmil
Structure of unliganded anti-gp120 CD4bs antibody DH522.1 Fab
分子名称: DH522.1 Fab fragment heavy chain, DH522.1 Fab fragment light chain
著者Nicely, N.I.
登録日2017-01-23
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.
Nat Commun, 8, 2017
3W3N
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BU of 3w3n by Molmil
Crystal structure of human TLR8 in complex with Resiquimod (R848) crystal form 3
分子名称: 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Tanji, H, Ohto, U, Shimizu, T.
登録日2012-12-22
公開日2013-04-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
Science, 339, 2013
3W4R
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BU of 3w4r by Molmil
Crystal structure of an insect chitinase from the Asian corn borer, Ostrinia furnacalis
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase
著者Chen, L, Liu, T, Zhou, Y, Shen, X, Yang, Q.
登録日2013-01-10
公開日2014-02-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting
Acta Crystallogr.,Sect.D, 70, 2014
5BZ4
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BU of 5bz4 by Molmil
Crystal structure of a T1-like thiolase (CoA-complex) from Mycobacterium smegmatis
分子名称: Beta-ketothiolase, COENZYME A
著者Janardan, N, Harijan, R.K, Kiema, T.R, Wierenga, R.K, Murthy, M.R.N.
登録日2015-06-11
公開日2016-05-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structural characterization of a mitochondrial 3-ketoacyl-CoA (T1)-like thiolase from Mycobacterium smegmatis
Acta Crystallogr.,Sect.D, 71, 2015
3WK8
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BU of 3wk8 by Molmil
Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor
分子名称: 6-(trifluoromethyl)-1,3-benzothiazol-2-amine, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ...
著者Amano, Y, Yamaguchi, T, Tanabe, E.
登録日2013-10-17
公開日2014-04-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography.
Bioorg.Med.Chem., 22, 2014
3WKN
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BU of 3wkn by Molmil
Crystal structure of the artificial protein AFFinger p17 (AF.p17) complexed with Fc fragment of human IgG
分子名称: AFFinger p17, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Watanabe, H, Honda, S.
登録日2013-10-29
公開日2014-10-29
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Adaptive Assembly: Maximizing the Potential of a Given Functional Peptide with a Tailor-Made Protein Scaffold.
Chem.Biol., 22, 2015
1ZIV
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BU of 1ziv by Molmil
Catalytic Domain of Human Calpain-9
分子名称: BETA-MERCAPTOETHANOL, CALCIUM ION, Calpain 9
著者Walker, J.R, Davis, T, Newman, E.M, Mackenzie, F, Dong, A, Choe, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2005-04-27
公開日2005-07-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The crystal structures of human calpains 1 and 9 imply diverse mechanisms of action and auto-inhibition.
J.Mol.Biol., 366, 2007
5C1A
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BU of 5c1a by Molmil
p97-N750D/R753D/M757D/Q760D in complex with ATP-gamma-S
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Haenzelmann, P, Schindelin, H.
登録日2015-06-13
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97.
Structure, 24, 2016
2CKJ
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BU of 2ckj by Molmil
Human milk xanthine oxidoreductase
分子名称: ACETIC ACID, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Pearson, A.R, Godber, B.L.J, Eisenthal, R, Taylor, G.L, Harrison, R.
登録日2006-04-19
公開日2007-05-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.59 Å)
主引用文献Human Milk Xanthine Dehydrogenase is Incompletely Converted to the Oxidase Form in the Absence of Proteolysis. A Structural Explanation.
To be Published
5GU3
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Crystal structure of Au(E).CL-apo-E45C/R52C-rHLFr
分子名称: 1,2-ETHANEDIOL, CADMIUM ION, Ferritin light chain, ...
著者Maity, B, Abe, S, Ueno, T.
登録日2016-08-24
公開日2017-03-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Observation of gold sub-nanocluster nucleation within a crystalline protein cage
Nat Commun, 8, 2017
1ZKM
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Structural Analysis of Escherichia Coli ThiF
分子名称: Adenylyltransferase thiF, ZINC ION
著者Duda, D.M, Walden, H, Sfondouris, J, Schulman, B.A.
登録日2005-05-03
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
5V18
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Structure of PHD2 in complex with 1,2,4-Triazolo-[1,5-a]pyridine
分子名称: 4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile, Egl nine homolog 1, FE (II) ION, ...
著者Skene, R.J.
登録日2017-03-01
公開日2017-06-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction.
J. Med. Chem., 60, 2017

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件を2024-08-21に公開中

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