PDB: 46188 件ウェブページステータス検索Chemie searchBIRD

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7SAN	Crystal structure of human hypoxanthine guanine phosphoribzosyltransferase in complex with (4S,7S)-7-hydroxy-4-((guanin-9-yl)methyl)-2,5-dioxaheptan-1,7-diphosphonate 分子名称: ({(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-[(2S)-2-hydroxy-2-phosphonoethoxy]propoxy}methyl)phosphonic acid, Hypoxanthine-guanine phosphoribosyltransferase 著者 Guddat, L.W, Keough, D.T. 登録日 2021-09-22 公開日 2022-05-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.58155513 Å) 主引用文献 Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6-Oxopurine Phosphoribosyltransferases. J.Med.Chem., 65, 2022
7O74	Structure of cyanase from Pseudomonas lactis 分子名称: CHLORIDE ION, Cyanate hydratase 著者 Brag, S, Driller, J.H, Pedersen, B.P. 登録日 2021-04-12 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Structure determination and analysis of unintentionally crystallized cyanase from Pseudomonas lactis To Be Published
6Q1F	Atomic structure of the Human Herpesvirus 6B Capsid and Capsid-Associated Tegument Complexes 分子名称: Large structural phosphoprotein, Major capsid protein, Small capsomere-interacting protein, ... 著者 Zhang, Y.B, Liu, W, Li, Z.H, Kumar, V, Alvarez-Cabrera, A.L, Leibovitch, E, Cui, Y.X, Mei, Y, Bi, G.Q, Jacobson, S, Zhou, Z.H. 登録日 2019-08-03 公開日 2019-12-11 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes. Nat Commun, 10, 2019
5LB6	HIF prolyl hydroxylase 2 (PHD2/EGLN1) R371H variant in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9) 分子名称: Egl nine homolog 1, GLYCEROL, MANGANESE (II) ION, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2016-06-15 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases. Nat Commun, 7, 2016
5LBE	HIF prolyl hydroxylase 2 (PHD2/EGLN1) G294E variant in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/FG2216) 分子名称: BICARBONATE ION, Egl nine homolog 1, MANGANESE (II) ION, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2016-06-15 公開日 2016-08-31 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases. Nat Commun, 7, 2016
5LBC	HIF prolyl hydroxylase 2 (PHD2/EGLN1) I280V/R281L/I292V variant in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/FG2216) 分子名称: BICARBONATE ION, CHLORIDE ION, Egl nine homolog 1, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2016-06-15 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.816 Å) 主引用文献 Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases. Nat Commun, 7, 2016
7S7B	Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1) 分子名称: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ... 著者 Puno, M.R, Lima, C.D. 登録日 2021-09-15 公開日 2022-06-15 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.06 Å) 主引用文献 Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell, 185, 2022
7SG5	Structure of PfCSP peptide 21 with antibody CIS43_Var2 分子名称: CIS43_Var2 Fab Heavy chain, CIS43_Var2 Fab Light chain, GLYCEROL, ... 著者 Tripathi, P, Kwong, P.D. 登録日 2021-10-05 公開日 2022-06-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Highly protective antimalarial antibodies via precision library generation and yeast display screening. J.Exp.Med., 219, 2022
7SG6	Structure of PfCSP peptide 21 with antibody CIS43_Var10 分子名称: CIS43_Var10 Fab Heavy chain, CIS43_Var10 Fab Light chain, GLYCEROL, ... 著者 Tripathi, P, Kwong, P.D. 登録日 2021-10-05 公開日 2022-06-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Highly protective antimalarial antibodies via precision library generation and yeast display screening. J.Exp.Med., 219, 2022
7S7C	Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2) 分子名称: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ... 著者 Puno, M.R, Lima, C.D. 登録日 2021-09-15 公開日 2022-06-15 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.62 Å) 主引用文献 Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell, 185, 2022
2IZN	MS2-RNA HAIRPIN (G-10) COMPLEX 分子名称: 5'-R(*AP*CP*AP*UP*CP*GP*CP*GP*AP*UP *UP*AP*CP*GP*GP*AP*UP*GP*U)-3', MS2 COAT PROTEIN 著者 Helgstrand, C, Grahn, E, Moss, T, Stonehouse, N.J, Tars, K, Stockley, P.G, Liljas, L. 登録日 2006-07-25 公開日 2006-07-27 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Investigating the Structural Basis of Purine Specificity in the Structures of MS2 Coat Protein RNA Translational Operator Complexes Nucleic Acids Res., 30, 2002
1J1L	Crystal structure of human Pirin: a Bcl-3 and Nuclear factor I interacting protein and a cupin superfamily member 分子名称: FE (II) ION, Pirin 著者 Pang, H, Bartlam, M, Zeng, Q, Gao, G.F, Rao, Z. 登録日 2002-12-10 公開日 2003-12-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor J.Biol.Chem., 279, 2004
2IZ8	MS2-RNA HAIRPIN (C-7) COMPLEX 分子名称: MS2 COAT PROTEIN, RNA, (5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*CP*UP*CP* AP*CP*CP*CP*AP*UP*GP*U)-3') 著者 Helgstrand, C, Grahn, E, Stonehouse, N.J, Stockley, P.G, Liljas, L. 登録日 2006-07-25 公開日 2006-07-27 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Investigating the Structural Basis of Purine Specificity in the Structures of MS2 Coat Protein RNA Translational Operator Hairpins Nucleic Acids Res., 30, 2002
1IX3	Crystal Structure of Rat Heme Oxygenase-1 in complex with Heme bound to Cyanide 分子名称: CYANIDE ION, HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE 著者 Sugishima, M, Sakamoto, H, Omata, Y, Hayashi, S, Noguchi, M, Fukuyama, K. 登録日 2002-06-10 公開日 2003-09-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1. Biochemistry, 42, 2003
7NXK	Crystal structure of human Cdk12/Cyclin K in complex with the inhibitor BSJ-01-175 分子名称: (E)-N-[4-[(1R,3R)-3-[[5-chloranyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]cyclohexyl]oxyphenyl]-4-(dimethylamino)but-2-enamide, Cyclin-K, Cyclin-dependent kinase 12 著者 Anand, K, Dust, S, Kaltheuner, I.H, Geyer, M. 登録日 2021-03-18 公開日 2021-05-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma. Eur.J.Med.Chem., 221, 2021
7OEV	Hepatitis B core protein mutant F97L with bound GSLLGRMKGA 分子名称: Capsid protein, GSLLGRMKGA 著者 Makbul, C, Bottcher, B. 登録日 2021-05-04 公開日 2021-05-19 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Conformational Plasticity of Hepatitis B Core Protein Spikes Promotes Peptide Binding Independent of the Secretion Phenotype. Microorganisms, 9, 2021
7NXJ	Crystal structure of human Cdk13/Cyclin K in complex with the inhibitor THZ531 分子名称: Cyclin-K, Cyclin-dependent kinase 13, N-[4-[(3R)-3-[[5-chloranyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamide 著者 Anand, K, Greifenberg, A.K, Kaltheuner, I.H, Geyer, M. 登録日 2021-03-18 公開日 2021-05-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma. Eur.J.Med.Chem., 221, 2021
7OEN	Hepatitis B core protein mutant P5T with bound GSLLGRMKGA 分子名称: Capsid protein, GSLLGRMKGA 著者 Bottcher, B, Makbul, C. 登録日 2021-05-03 公開日 2021-05-19 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Conformational Plasticity of Hepatitis B Core Protein Spikes Promotes Peptide Binding Independent of the Secretion Phenotype. Microorganisms, 9, 2021
7OCO	Hepatitis B core protein -low secretion phenotype L60V 分子名称: Capsid protein 著者 Bottcher, B, Makbul, C. 登録日 2021-04-28 公開日 2021-05-26 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Conformational Plasticity of Hepatitis B Core Protein Spikes Promotes Peptide Binding Independent of the Secretion Phenotype. Microorganisms, 9, 2021
7OD8	Hepatitis B core Protein mutant L60V + GSLLGRMKGA 分子名称: Capsid protein, peptide GSLLGRMKGA 著者 Bottcher, B, Makbul, C. 登録日 2021-04-28 公開日 2021-05-26 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Conformational Plasticity of Hepatitis B Core Protein Spikes Promotes Peptide Binding Independent of the Secretion Phenotype. Microorganisms, 9, 2021
7NPT	Cytosolic bridge of an intact ESX-5 inner membrane complex 分子名称: ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5 著者 Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C. 登録日 2021-02-28 公開日 2021-05-26 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Structure and dynamics of a mycobacterial type VII secretion system. Nature, 593, 2021
7OCW	Hepatitis B core protein -low secretion phenotype P5T 分子名称: Capsid protein 著者 Bottcher, B, Makbul, C. 登録日 2021-04-28 公開日 2021-05-26 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Conformational Plasticity of Hepatitis B Core Protein Spikes Promotes Peptide Binding Independent of the Secretion Phenotype. Microorganisms, 9, 2021
7OD6	Hepatitis B core protein + GSLLGRMKGA 分子名称: Capsid protein, Inhibitory Peptide P2 (GSLLGRMKGA) 著者 Bottcher, B, Makbul, C. 登録日 2021-04-28 公開日 2021-05-26 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Conformational Plasticity of Hepatitis B Core Protein Spikes Promotes Peptide Binding Independent of the Secretion Phenotype. Microorganisms, 9, 2021
7OD7	Hepatitis B core protein + SLLGRM 分子名称: Capsid protein, SLLRGM 著者 Bottcher, B, Makbul, C. 登録日 2021-04-28 公開日 2021-05-26 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Conformational Plasticity of Hepatitis B Core Protein Spikes Promotes Peptide Binding Independent of the Secretion Phenotype. Microorganisms, 9, 2021
1IX9	Crystal Structure of the E. coli Manganase(III) superoxide dismutase mutant Y174F at 0.90 angstroms resolution. 分子名称: MANGANESE (II) ION, Superoxide Dismutase 著者 Anderson, B.F, Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B. 登録日 2002-06-17 公開日 2002-12-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (0.9 Å) 主引用文献 Structures at 0.90 A resolution of the oxidised and reduced forms of the Y174F mutant of the manganese superoxide dismutase from Escherichia coli To be Published

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