2Z3P
 
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2BXA
 | | Human serum albumin complexed with 3-carboxy-4-methyl-5-propyl-2- furanpropanoic acid (CMPF) | | 分子名称: | 3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC, SERUM ALBUMIN | | 著者 | Ghuman, J, Zunszain, P.A, Petitpas, I, Bhattacharya, A.A, Otagiri, M, Curry, S. | | 登録日 | 2005-07-26 | | 公開日 | 2005-09-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
J.Mol.Biol., 353, 2005
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3M0N
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1RXY
 | | E. coli uridine phosphorylase: type-B native | | 分子名称: | ACETATE ION, GLYCEROL, POTASSIUM ION, ... | | 著者 | Caradoc-Davies, T.T, Cutfield, S.M, Lamont, I.L, Cutfield, J.F. | | 登録日 | 2003-12-18 | | 公開日 | 2004-04-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium
J.Mol.Biol., 337, 2004
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1S51
 | | Thr24Ser Bacteriorhodopsin | | 分子名称: | RETINAL, bacteriorhodopsin | | 著者 | Yohannan, S, Faham, S, Yang, D, Grosfeld, D, Chamberlain, A.K, Bowie, J.U. | | 登録日 | 2004-01-19 | | 公開日 | 2004-03-02 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A C(alpha)-H.O Hydrogen Bond in a Membrane Protein Is Not Stabilizing
J.Am.Chem.Soc., 126, 2004
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5HJ7
 | | Glutamate Racemase Mycobacterium tuberculosis (MurI) with bound D-glutamate, 2.3 Angstrom resolution, X-ray diffraction | | 分子名称: | D-GLUTAMIC ACID, Glutamate racemase | | 著者 | Poen, S, Nakatani, Y, Krause, K. | | 登録日 | 2016-01-12 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Exploring the structure of glutamate racemase from Mycobacterium tuberculosis as a template for anti-mycobacterial drug discovery.
Biochem. J., 473, 2016
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5HNQ
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5HR1
 | | Crystal structure of thioredoxin L107A mutant | | 分子名称: | COPPER (II) ION, Thioredoxin-1 | | 著者 | Noguera, M.E, Vazquez, D.S, Howard, E.I, Cousido-Siah, A, Mitschler, A, Podjarny, A, Santos, J. | | 登録日 | 2016-01-22 | | 公開日 | 2017-02-22 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.144 Å) | | 主引用文献 | Structural variability of E. coli thioredoxin captured in the crystal structures of single-point mutants.
Sci Rep, 7, 2017
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3M6A
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2Z3O
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5HVQ
 | | Alternative model of the MAGE-G1 NSE-1 complex | | 分子名称: | Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ZINC ION | | 著者 | Newman, J.A, Cooper, C.D.O, Roos, A.K, Aitkenhead, H, Oppermann, U.C.T, Cho, H.J, Osman, R, Gileadi, O. | | 登録日 | 2016-01-28 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.923 Å) | | 主引用文献 | Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Plos One, 11, 2016
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1S54
 | | Thr24Ala Bacteriorhodopsin | | 分子名称: | RETINAL, bacteriorhodopsin | | 著者 | Yohannan, S, Faham, S, Yang, D, Grosfeld, D, Chamberlain, A.K, Bowie, J.U. | | 登録日 | 2004-01-19 | | 公開日 | 2004-03-02 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A C(alpha)-H.O Hydrogen Bond in a Membrane Protein Is Not Stabilizing
J.Am.Chem.Soc., 126, 2004
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7KPV
 | | Structure of kinase and Central lobes of yeast CKM | | 分子名称: | Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ... | | 著者 | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | | 登録日 | 2020-11-12 | | 公開日 | 2021-01-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module.
Sci Adv, 7, 2021
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7KXE
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3MC9
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1S0A
 | | Crystal Structure of the Y17F Mutant of 7,8-Diaminopelargonic Acid Synthase | | 分子名称: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION | | 著者 | Sandmark, J, Eliot, A.C, Famm, K, Schneider, G, Kirsch, J.F. | | 登録日 | 2003-12-30 | | 公開日 | 2004-03-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
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7B9O
 | | Crystal structure of Retinoic Acid Receptor alpha (RXRA) in complexed with S169 inhibitor | | 分子名称: | 3-(5-(3,5-bis(trifluoromethyl)phenyl)-4-phenyloxazol-2-yl)propanoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | | 著者 | Ni, X, Chaikuad, A, Schierle, S, Merk, D, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2020-12-14 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Oxaprozin Analogues as Selective RXR Agonists with Superior Properties and Pharmacokinetics.
J.Med.Chem., 64, 2021
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4KRZ
 | | Apo crystal structure of pyruvate kinase (PYK) from Trypanosoma cruzi | | 分子名称: | GLYCEROL, POTASSIUM ION, Pyruvate kinase | | 著者 | Zhong, W, Morgan, H.P, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | | 登録日 | 2013-05-17 | | 公開日 | 2014-11-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of pyruvate kinases display evolutionarily divergent allosteric strategies.
R Soc Open Sci, 1, 2014
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5DV8
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3MH6
 | | HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues | | 分子名称: | DIISOPROPYL PHOSPHONATE, Protease do | | 著者 | Krojer, T, Sawa, J, Huber, R, Clausen, T. | | 登録日 | 2010-04-07 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010
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3MKV
 | | Crystal structure of amidohydrolase eaj56179 | | 分子名称: | CARBONATE ION, GLYCEROL, PUTATIVE AMIDOHYDROLASE, ... | | 著者 | Patskovsky, Y, Bonanno, J, Ozyurt, S, Sauder, J.M, Freeman, J, Wu, B, Smith, D, Bain, K, Rodgers, L, Wasserman, S.R, Raushel, F.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2010-04-15 | | 公開日 | 2010-04-28 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Functional identification and structure determination of two novel prolidases from cog1228 in the amidohydrolase superfamily .
Biochemistry, 49, 2010
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2BFR
 | | The Macro domain is an ADP-ribose binding module | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, HYPOTHETICAL PROTEIN AF1521, MAGNESIUM ION | | 著者 | Karras, G.I, Buhecha, H.R, Allen, M.D, Pugieux, C, Sait, F, Bycroft, M, Ladurner, A.G. | | 登録日 | 2004-12-10 | | 公開日 | 2004-12-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Macro Domain is an Adp-Ribose Binding Module.
Embo J., 24, 2005
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2BXF
 | | Human serum albumin complexed with diazepam | | 分子名称: | 7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE, SERUM ALBUMIN | | 著者 | Ghuman, J, Zunszain, P.A, Petitpas, I, Bhattacharya, A.A, Curry, S. | | 登録日 | 2005-07-26 | | 公開日 | 2005-09-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
J.Mol.Biol., 353, 2005
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3MLF
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5HJF
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