PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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5ETM	E. coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.46 angstrom resolution 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 2-azanyl-8-[(4-fluorophenyl)methylsulfanyl]-1,7-dihydropurin-6-one, CALCIUM ION, ... 著者 Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2015-11-17 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. J.Med.Chem., 59, 2016
5ETN	E. coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.40 angstrom resolution 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 2-azanyl-8-[(4-chlorophenyl)methylsulfanyl]-1,9-dihydropurin-6-one, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2015-11-17 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. J.Med.Chem., 59, 2016
5ETK	E. coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.09 angstrom resolution 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 2-azanyl-8-[(2-fluorophenyl)methylsulfanyl]-1,9-dihydropurin-6-one, CALCIUM ION, ... 著者 Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2015-11-17 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. J.Med.Chem., 59, 2016
3IDG	Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ALDKWD 分子名称: 2F5 Fab heavy chain, 2F5 Fab light chain, gp41 MPER peptide 著者 Julien, J.P, Bryson, S, Pai, E.F. 登録日 2009-07-21 公開日 2010-03-02 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications. J.Virol., 83, 2009
5ETO	E. coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.07 angstrom resolution 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 4-[(2-azanyl-6-oxidanylidene-1,9-dihydropurin-8-yl)sulfanylmethyl]-3-fluoranyl-benzenecarbonitrile, CALCIUM ION, ... 著者 Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2015-11-17 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. J.Med.Chem., 59, 2016
6BZC	Crystal Structure of Glucose-6-phosphate Isomerase from Elizabethkingia anophelis with bound Glucose-6-phosphate 分子名称: 1,2-ETHANEDIOL, 6-O-phosphono-alpha-D-glucopyranose, GLYCEROL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-12-22 公開日 2018-01-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal Structure of Glucose-6-phosphate Isomerase from Elizabethkingia anophelis with bound Glucose-6-phosphate to be published
9M74	Crystal structure of MBP-fused BIL1/BZR1 (21-104) in complex with double-stranded DNA contaning CACAGCTGTG 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*CP*AP*CP*AP*GP*CP*TP*GP*TP*GP*AP*AP*A)-3'), Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1, ... 著者 Shohei, N, Masaru, T, Takuya, M. 登録日 2025-03-09 公開日 2025-09-10 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Single cis-elements in brassinosteroid-induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA-binding domain. Febs Lett., 2025
8I0S	The cryo-EM structure of human Bact-II complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0W	The cryo-EM structure of human C complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
5ETS	S. aureus 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.95 angstrom resolution 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 2-azanyl-8-[(4-chlorophenyl)methylsulfanyl]-1,9-dihydropurin-6-one, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... 著者 Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2015-11-18 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. J.Med.Chem., 59, 2016
5ETT	S. aureus 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.55 angstrom resolution 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 4-[(2-azanyl-6-oxidanylidene-1,9-dihydropurin-8-yl)sulfanylmethyl]-3-fluoranyl-benzenecarbonitrile, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... 著者 Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2015-11-18 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. J.Med.Chem., 59, 2016
4BDC	Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, N-(furan-2-ylmethyl)quinoxaline-6-carboxamide, ... 著者 Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M. 登録日 2012-10-05 公開日 2013-06-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2. Plos One, 8, 2013
5ETP	E. coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.05 angstrom resolution 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 2-azanyl-8-[2-(4-bromophenyl)-2-oxidanylidene-ethyl]sulfanyl-1,9-dihydropurin-6-one, CALCIUM ION, ... 著者 Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2015-11-17 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. J.Med.Chem., 59, 2016
4CH3	Structure of pyrrolysyl-tRNA synthetase in complex with adenylated butyryl lysine 分子名称: 1,2-ETHANEDIOL, 5'-O-({[(2R)-2-amino-6-(butanoylamino)hexanoyl]oxy}phosphinato)adenosine, MAGNESIUM ION, ... 著者 Fluegel, V, Vrabel, M, Schneider, S. 登録日 2013-11-28 公開日 2014-03-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structural Basis for the Site-Specific Incorporation of Lysine Derivatives Into Proteins. Plos One, 9, 2014
6M68	The Cryo-EM Structure of Human Pannexin 1 in the Presence of CBX 分子名称: Pannexin-1 著者 Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S. 登録日 2020-03-13 公開日 2020-04-15 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Cryo-EM structures of human pannexin 1 channel. Cell Res., 30, 2020
5OFJ	Crystal structure of N-terminal domain of bifunctional CbXyn10C 分子名称: 1,2-ETHANEDIOL, CITRATE ANION, Glycoside hydrolase family 48 著者 Hakulinen, N, Penttinen, L, Rouvinen, J. 登録日 2017-07-11 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Insights into the roles of non-catalytic residues in the active site of a GH10 xylanase with activity on cellulose. J. Biol. Chem., 292, 2017
7UPL	SARS-Cov2 Omicron varient S protein structure in complex with neutralizing monoclonal antibody 002-S21F2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... 著者 Patel, A, Ortlund, E. 登録日 2022-04-15 公開日 2022-08-10 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody. Sci Adv, 8, 2022
9M73	Crystal structure of MBP-fused BIL1/BZR1 (21-104) in complex with double-stranded DNA contaning CACATATGTG 分子名称: 1,2-ETHANEDIOL, E-box(CATATG)-containing DNA, Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1, ... 著者 Shohei, N, Masaru, T, Takuya, M. 登録日 2025-03-09 公開日 2025-09-10 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Single cis-elements in brassinosteroid-induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA-binding domain. Febs Lett., 2025
7FAV	Crystal Structure of Rubella Protease 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Quek, J.P. 登録日 2021-07-07 公開日 2022-07-13 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold. J.Biol.Chem., 298, 2022
1M5R	Ternary complex of T4 phage BGT with UDP and a 13 mer DNA duplex 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*TP*C)-3', ... 著者 Lariviere, L, Morera, S. 登録日 2002-07-10 公開日 2002-12-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Base-flipping mechanism for the T4 phage beta-glucosyltransferase and identification of a transition state analog J.Mol.Biol., 324, 2002
6BOV	Human APE1 substrate complex with an A/G mismatch adjacent the THF 分子名称: 21-mer DNA, DI(HYDROXYETHYL)ETHER, DNA-(apurinic or apyrimidinic site) lyase 著者 Freudenthal, B.D, Whitaker, A.M, Fairlamb, M.S. 登録日 2017-11-20 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.975 Å) 主引用文献 Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches. Acta Crystallogr D Struct Biol, 74, 2018
5FDX	Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution. 分子名称: 1,2-ETHANEDIOL, 3-[(4-methylpiperazin-1-yl)methyl]-~{N}-[(4~{R})-4-methyl-2-pyrimidin-5-yl-3,4-dihydro-1~{H}-isoquinolin-7-yl]-5-(trifluoromethyl)benzamide, DI(HYDROXYETHYL)ETHER, ... 著者 Bartual, S.G, Pinkas, D.M, Wang, Z, Ding, K, Mahajan, P, Kupinska, K, Mukhopadhyay, S, Strain-Damerell, C, Chalk, R, Borkowska, O, Talon, R, Kopec, J, Williams, E, Tallant, C, Chaikuad, A, Sorell, F, Newman, J, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) 登録日 2015-12-16 公開日 2016-10-26 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution. To Be Published
2VLH	Quinonoid intermediate of Citrobacter freundii tyrosine phenol-lyase formed with methionine 分子名称: (2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}-4-(METHYLSULFANYL)BUTANOIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, POTASSIUM ION, ... 著者 Milic, D, Demidkina, T.V, Matkovic-Calogovic, D, Antson, A.A. 登録日 2008-01-14 公開日 2008-08-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Insights Into the Catalytic Mechanism of Tyrosine Phenol-Lyase from X-Ray Structures of Quinonoid Intermediates. J.Biol.Chem., 283, 2008
5VA6	CRYSTAL STRUCTURE OF ATXR5 IN COMPLEX WITH HISTONE H3.1 MONO-METHYLATED ON R26 分子名称: Histone H3.1, Probable Histone-lysine N-methyltransferase ATXR5, S-ADENOSYL-L-HOMOCYSTEINE 著者 Bergamin, E, Sarvan, S, Malette, J, Eram, M, Yeung, S, Mongeon, V, Joshi, M, Brunzelle, J.S, Michaels, S.D, Blais, A, Vedadi, M, Couture, J.-F. 登録日 2017-03-24 公開日 2017-04-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis for the methylation specificity of ATXR5 for histone H3. Nucleic Acids Res., 45, 2017
4Z3O	Quinolone(Moxifloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae 分子名称: 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA topoisomerase 4 subunit B,ParE30-ParC55 fused topo IV from S. pneumoniae, E-site DNA, ... 著者 Laponogov, I, Veselkov, D.A, Pan, X.-S, Selvarajah, J, Crevel, I.M.-T, Fisher, L.M, Sanderson, M.R. 登録日 2015-03-31 公開日 2016-09-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.44 Å) 主引用文献 Structural studies of the drug-stabilized cleavage complexes of topoisomerase IV and gyrase from Streptococcus pneumoniae To Be Published

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