PDB: 316 件ウェブページステータス検索Chemie searchBIRD

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3QGA	3.0 A Model of Iron Containing Urease UreA2B2 from Helicobacter mustelae 分子名称: FE (III) ION, Fusion of urease beta and gamma subunits, Urease subunit beta 2 著者 Tronrud, D.E, Robbins, A, Karplus, P.A. 登録日 2011-01-24 公開日 2011-08-10 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Iron-containing urease in a pathogenic bacterium. Proc.Natl.Acad.Sci.USA, 108, 2011
7KNS	Cryo-EM structure of jack bean urease 分子名称: NICKEL (II) ION, PHOSPHATE ION, Urease 著者 Feathers, J.R, Spoth, K.A, Fromme, J.C. 登録日 2020-11-05 公開日 2021-03-24 最終更新日 2021-04-21 実験手法 ELECTRON MICROSCOPY (2.77 Å) 主引用文献 Experimental evaluation of super-resolution imaging and magnification choice in single-particle cryo-EM. J Struct Biol X, 5, 2021
3UBP	DIAMIDOPHOSPHATE INHIBITED BACILLUS PASTEURII UREASE 分子名称: DIAMIDOPHOSPHATE, NICKEL (II) ION, PROTEIN (UREASE ALPHA SUBUNIT), ... 著者 Benini, S, Rypniewski, W.R, Wilson, K.S, Miletti, S, Mangani, S, Ciurli, S. 登録日 1998-12-16 公開日 1999-12-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A new proposal for urease mechanism based on the crystal structures of the native and inhibited enzyme from Bacillus pasteurii: why urea hydrolysis costs two nickels. Structure Fold.Des., 7, 1999
3D6N	Crystal Structure of Aquifex Dihydroorotase Activated by Aspartate Transcarbamoylase 分子名称: Aspartate carbamoyltransferase, CITRATE ANION, Dihydroorotase, ... 著者 Edwards, B.F.P. 登録日 2008-05-20 公開日 2009-01-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Dihydroorotase from the hyperthermophile Aquifiex aeolicus is activated by stoichiometric association with aspartate transcarbamoylase and forms a one-pot reactor for pyrimidine biosynthesis. Biochemistry, 48, 2009
1A5O	K217C VARIANT OF KLEBSIELLA AEROGENES UREASE, CHEMICALLY RESCUED BY FORMATE AND NICKEL 分子名称: FORMIC ACID, NICKEL (II) ION, UREASE (ALPHA SUBUNIT), ... 著者 Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P. 登録日 1998-02-17 公開日 1998-05-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand. Biochemistry, 37, 1998
1A5N	K217A VARIANT OF KLEBSIELLA AEROGENES UREASE, CHEMICALLY RESCUED BY FORMATE AND NICKEL 分子名称: FORMIC ACID, NICKEL (II) ION, UREASE (ALPHA SUBUNIT), ... 著者 Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P. 登録日 1998-02-17 公開日 1998-05-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand. Biochemistry, 37, 1998
1A5K	K217E VARIANT OF KLEBSIELLA AEROGENES UREASE 分子名称: UREASE (ALPHA SUBUNIT), UREASE (BETA SUBUNIT), UREASE (GAMMA SUBUNIT) 著者 Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P. 登録日 1998-02-17 公開日 1998-05-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand. Biochemistry, 37, 1998
1A5L	K217C VARIANT OF KLEBSIELLA AEROGENES UREASE 分子名称: UREASE (ALPHA SUBUNIT), UREASE (BETA SUBUNIT), UREASE (GAMMA SUBUNIT) 著者 Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P. 登録日 1998-02-17 公開日 1998-05-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand. Biochemistry, 37, 1998
5FSE	2.07 A resolution 1,4-Benzoquinone inhibited Sporosarcina pasteurii urease 分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ... 著者 Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. 登録日 2016-01-04 公開日 2016-03-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Inactivation of Urease by 1,4-Benzoquinone: Chemistry at the Protein Surface. Dalton Trans, 45, 2016
1A5M	K217A VARIANT OF KLEBSIELLA AEROGENES UREASE 分子名称: UREASE (ALPHA SUBUNIT), UREASE (BETA SUBUNIT), UREASE (GAMMA SUBUNIT) 著者 Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P. 登録日 1998-02-17 公開日 1998-05-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand. Biochemistry, 37, 1998
5FSD	1.75 A resolution 2,5-dihydroxybenzensulfonate inhibited Sporosarcina pasteurii urease 分子名称: 1,2-ETHANEDIOL, 2,5-dihydroxybenzenesulfonic acid, HYDROXIDE ION, ... 著者 Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. 登録日 2016-01-04 公開日 2016-03-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Inactivation of Urease by 1,4-Benzoquinone: Chemistry at the Protein Surface. Dalton Trans, 45, 2016
6QSU	Helicobacter pylori urease with BME bound in the active site 分子名称: BETA-MERCAPTOETHANOL, NICKEL (II) ION, Urease subunit alpha, ... 著者 Luecke, H, Cunha, E. 登録日 2019-02-22 公開日 2021-01-20 最終更新日 2021-02-03 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 angstrom resolution. Nat Commun, 12, 2021
4UBP	STRUCTURE OF BACILLUS PASTEURII UREASE INHIBITED WITH ACETOHYDROXAMIC ACID AT 1.55 A RESOLUTION 分子名称: ACETOHYDROXAMIC ACID, NICKEL (II) ION, PROTEIN (UREASE (CHAIN A)), ... 著者 Benini, S, Rypniewski, W.R, Wilson, K.S, Ciurli, S, Mangani, S. 登録日 1999-02-25 公開日 2000-03-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The complex of Bacillus pasteurii urease with acetohydroxamate anion from X-ray data at 1.55 A resolution. J.Biol.Inorg.Chem., 5, 2000
6QDY	The crystal structure of Sporosarcina pasteurii urease in complex with its substrate urea 分子名称: 1,2-ETHANEDIOL, FLUORIDE ION, NICKEL (II) ION, ... 著者 Mazzei, L, Cianci, M, Benini, S, Ciurli, S. 登録日 2019-01-03 公開日 2019-11-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.416 Å) 主引用文献 The Structure of the Elusive Urease-Urea Complex Unveils the Mechanism of a Paradigmatic Nickel-Dependent Enzyme. Angew.Chem.Int.Ed.Engl., 58, 2019
6RP1	1.49 A RESOLUTION OF SPOROSARCINA PASTEURII UREASE INHIBITED IN THE PRESENCE OF NBPTO AT pH 6.5 分子名称: 1,2-ETHANEDIOL, DIAMIDOPHOSPHATE, NICKEL (II) ION, ... 著者 Mazzei, L, Cianci, M, Benini, S, Ciurli, S. 登録日 2019-05-13 公開日 2020-03-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 The Impact of pH on Catalytically Critical Protein Conformational Changes: The Case of the Urease, a Nickel Enzyme. Chemistry, 25, 2019
6RKG	1.32 A RESOLUTION OF SPOROSARCINA PASTEURII UREASE INHIBITED IN THE PRESENCE OF NBPTO AT pH 7.5 分子名称: 1,2-ETHANEDIOL, DIAMIDOPHOSPHATE, NICKEL (II) ION, ... 著者 Mazzei, L, Cianci, M, Benini, S, Ciurli, S. 登録日 2019-04-30 公開日 2020-03-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 The Impact of pH on Catalytically Critical Protein Conformational Changes: The Case of the Urease, a Nickel Enzyme. Chemistry, 25, 2019
6YL3	High resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica 分子名称: NICKEL (II) ION, Urease subunit alpha, Urease subunit beta, ... 著者 Righetto, R.D, Anton, L, Adaixo, R, Jakob, R, Zivanov, J, Mahi, M.A, Ringler, P, Schwede, T, Maier, T, Stahlberg, H. 登録日 2020-04-06 公開日 2020-05-06 最終更新日 2020-10-21 実験手法 ELECTRON MICROSCOPY (1.98 Å) 主引用文献 High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica. Nat Commun, 11, 2020
6ZJA	Helicobacter pylori urease with inhibitor bound in the active site 分子名称: 2-{[1-(3,5-dimethylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-hydroxyacetamide, NICKEL (II) ION, Urease subunit alpha, ... 著者 Luecke, H, Cunha, E. 登録日 2020-06-28 公開日 2020-12-23 最終更新日 2021-02-03 実験手法 ELECTRON MICROSCOPY (2 Å) 主引用文献 Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 angstrom resolution. Nat Commun, 12, 2021
2UBP	STRUCTURE OF NATIVE UREASE FROM BACILLUS PASTEURII 分子名称: NICKEL (II) ION, PROTEIN (UREASE ALPHA SUBUNIT), PROTEIN (UREASE BETA SUBUNIT), ... 著者 Benini, S, Rypniewski, W.R, Wilson, K.S, Ciurli, S, Mangani, S. 登録日 1998-11-04 公開日 1999-11-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A new proposal for urease mechanism based on the crystal structures of the native and inhibited enzyme from Bacillus pasteurii: why urea hydrolysis costs two nickels. Structure Fold.Des., 7, 1999
6ZO1	1.61 A resolution 3,5-dimethylcatechol (3,5-dimethylbenzene-1,2-diol) inhibited Sporosarcina pasteurii urease 分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ... 著者 Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. 登録日 2020-07-07 公開日 2020-12-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies. Angew.Chem.Int.Ed.Engl., 60, 2021
6ZNZ	1.89 A resolution 4-methylcatechol (4-methylbenzene-1,2-diol) inhibited Sporosarcina pasteurii urease 分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ... 著者 Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. 登録日 2020-07-07 公開日 2020-12-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies. Angew.Chem.Int.Ed.Engl., 60, 2021
6ZO3	1.55 A resolution 3,6-dimethylcatechol (3,6-dimethylbenzene-1,2-diol) inhibited Sporosarcina pasteurii urease 分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ... 著者 Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. 登録日 2020-07-07 公開日 2020-12-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies. Angew.Chem.Int.Ed.Engl., 60, 2021
6ZO0	2.23 A resolution 3,4-dimethylcatechol (3,4-dimethylbenzene-1,2-diol) inhibited Sporosarcina pasteurii urease 分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ... 著者 Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. 登録日 2020-07-07 公開日 2020-12-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies. Angew.Chem.Int.Ed.Engl., 60, 2021
6ZNY	1.50 A resolution 3-methylcatechol (3-methylbenzene-1,2-diol) inhibited Sporosarcina pasteurii urease 分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ... 著者 Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. 登録日 2020-07-07 公開日 2020-12-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies. Angew.Chem.Int.Ed.Engl., 60, 2021
6ZO2	1.65 A resolution 4,5-dimethylcatechol (4,5-dimethylbenzene-1,2-diol) inhibited Sporosarcina pasteurii urease 分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ... 著者 Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. 登録日 2020-07-07 公開日 2020-12-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies. Angew.Chem.Int.Ed.Engl., 60, 2021

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