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1V3K
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Crystal structure of F283Y mutant cyclodextrin glycosyltransferase
分子名称: CALCIUM ION, Cyclomaltodextrin glucanotransferase
著者Kanai, R, Haga, K, Akiba, T, Yamane, K, Harata, K.
登録日2003-11-03
公開日2004-08-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of Phe283 in enzymatic reaction of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp.1011: substrate binding and arrangement of the catalytic site
PROTEIN SCI., 13, 2004
1XGZ
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Structure of the N298S variant of human pancreatic alpha-amylase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, pancreatic, ...
著者Maurus, R, Begum, A, Kuo, H.H, Racaza, A, Numao, S, Overall, C.M, Withers, S.G, Brayer, G.D.
登録日2004-09-17
公開日2005-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase
PROTEIN SCI., 14, 2005
1QI4
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MUTANT (E219G) MALTOTETRAOSE-FORMING EXO-AMYLASE IN COMPLEX WITH MALTOTETRAOSE
分子名称: CALCIUM ION, PROTEIN (EXO-MALTOTETRAOHYDROLASE), alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Hasegawa, K, Kubota, M, Matsuura, Y.
登録日1999-06-01
公開日1999-11-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Roles of catalytic residues in alpha-amylases as evidenced by the structures of the product-complexed mutants of a maltotetraose-forming amylase.
Protein Eng., 12, 1999
1XH0
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Structure of the N298S variant of human pancreatic alpha-amylase complexed with acarbose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED HEXASACCHARIDE, Alpha-amylase, ...
著者Maurus, R, Begum, A, Kuo, H.H, Racaza, A, Numao, S, Overall, C.M, Withers, S.G, Brayer, G.D.
登録日2004-09-17
公開日2005-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase
PROTEIN SCI., 14, 2005
1I75
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CRYSTAL STRUCTURE OF CYCLODEXTRIN GLUCANOTRANSFERASE FROM ALKALOPHILIC BACILLUS SP.#1011 COMPLEXED WITH 1-DEOXYNOJIRIMYCIN
分子名称: 1-DEOXYNOJIRIMYCIN, CALCIUM ION, CYCLODEXTRIN GLUCANOTRANSFERASE
著者Kanai, R, Haga, K, Yamane, K, Harata, K.
登録日2001-03-08
公開日2001-04-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of cyclodextrin glucanotransferase from alkalophilic Bacillus sp. 1011 complexed with 1-deoxynojirimycin at 2.0 A resolution.
J.Biochem.(Tokyo), 129, 2001
1AQH
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ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS
分子名称: ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION
著者Aghajari, N, Haser, R.
登録日1997-07-30
公開日1999-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor.
Protein Sci., 7, 1998
2ZE0
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Alpha-glucosidase GSJ
分子名称: Alpha-glucosidase, CALCIUM ION
著者Shirai, T, Hung, V.S, Morinaka, K, Kobayashi, T, Ito, S.
登録日2007-12-04
公開日2007-12-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of GH13 alpha-glucosidase GSJ from one of the deepest sea bacteria
Proteins, 73, 2008
1UOK
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CRYSTAL STRUCTURE OF B. CEREUS OLIGO-1,6-GLUCOSIDASE
分子名称: OLIGO-1,6-GLUCOSIDASE
著者Watanabe, K, Hata, Y, Kizaki, H, Katsube, Y, Suzuki, Y.
登録日1998-07-28
公開日1999-02-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The refined crystal structure of Bacillus cereus oligo-1,6-glucosidase at 2.0 A resolution: structural characterization of proline-substitution sites for protein thermostabilization.
J.Mol.Biol., 269, 1997
1BSI
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HUMAN PANCREATIC ALPHA-AMYLASE FROM PICHIA PASTORIS, GLYCOSYLATED PROTEIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, CALCIUM ION, ...
著者Rydberg, E.H, Sidhu, G, Vo, H.C, Hewitt, J, Cote, H.C.F, Wang, Y, Numao, S, Macgillivray, R.T.A, Overall, C.M, Brayer, G.D, Withers, S.G.
登録日1998-08-28
公開日1999-05-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cloning, mutagenesis, and structural analysis of human pancreatic alpha-amylase expressed in Pichia pastoris.
Protein Sci., 8, 1999
8ORP
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Crystal structure of Drosophila melanogaster alpha-amylase in complex with the inhibitor acarbose
分子名称: 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ...
著者Aghajari, N, Haser, R.
登録日2023-04-16
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Functional Characterization of Drosophila melanogaster alpha-Amylase.
Molecules, 28, 2023
3DHU
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Crystal structure of an alpha-amylase from Lactobacillus plantarum
分子名称: Alpha-amylase
著者Bonanno, J.B, Dickey, M, Bain, K.T, Iizuka, M, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-06-18
公開日2008-08-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of an alpha-amylase from Lactobacillus plantarum
To be Published
3BAW
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Human pancreatic alpha-amylase complexed with azide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AZIDE ION, CALCIUM ION, ...
著者Maurus, R, Brayer, G.D.
登録日2007-11-08
公開日2008-03-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
1JGI
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Crystal Structure of the Active Site Mutant Glu328Gln of Amylosucrase from Neisseria polysaccharea in Complex with the Natural Substrate Sucrose
分子名称: amylosucrase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
著者Mirza, O, Skov, L.K, Gajhede, M.
登録日2001-06-25
公開日2001-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of amylosucrase from Neisseria polysaccharea in complex with D-glucose and the active site mutant Glu328Gln in complex with the natural substrate sucrose.
Biochemistry, 40, 2001
3OLD
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Crystal structure of alpha-amylase in complex with acarviostatin I03
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, ...
著者Qin, X, Ren, L.
登録日2010-08-26
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of human pancreatic alpha-amylase in complex with acarviostatins: Implications for drug design against type II diabetes
J.Struct.Biol., 174, 2011
1V3J
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Crystal structure of F283L mutant cyclodextrin glycosyltransferase
分子名称: CALCIUM ION, Cyclomaltodextrin glucanotransferase
著者Kanai, R, Haga, K, Akiba, T, Yamane, K, Harata, K.
登録日2003-11-03
公開日2004-08-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of Phe283 in enzymatic reaction of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp.1011: Substrate binding and arrangement of the catalytic site
PROTEIN SCI., 13, 2004
1DED
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CRYSTAL STRUCTURE OF ALKALOPHILIC ASPARAGINE 233-REPLACED CYCLODEXTRIN GLUCANOTRANSFERASE COMPLEXED WITH AN INHIBITOR, ACARBOSE, AT 2.0 A RESOLUTION
分子名称: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, CALCIUM ION, CYCLODEXTRIN GLUCANOTRANSFERASE
著者Ishii, N, Haga, K, Yamane, K, Harata, K.
登録日1999-11-14
公開日2000-04-07
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of alkalophilic asparagine 233-replaced cyclodextrin glucanotransferase complexed with an inhibitor, acarbose, at 2.0 A resolution.
J.Biochem.(Tokyo), 127, 2000
2PWE
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Crystal structure of the MutB E254Q mutant in complex with the substrate sucrose
分子名称: CALCIUM ION, Sucrose isomerase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
著者Ravaud, S, Robert, X, Haser, R, Aghajari, N.
登録日2007-05-11
公開日2007-06-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization.
J.Biol.Chem., 282, 2007
2CPU
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SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT
分子名称: ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION
著者Brayer, G.D, Sidhu, G, Maurus, R, Rydberg, E.H, Braun, C, Wang, Y, Nguyen, N.T, Overall, C.M, Withers, S.G.
登録日1999-06-08
公開日2001-06-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques.
Biochemistry, 39, 2000
2PWH
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Crystal structure of the trehalulose synthase MutB from Pseudomonas mesoacidophila MX-45
分子名称: CALCIUM ION, Sucrose isomerase
著者Ravaud, S, Robert, X, Haser, R, Aghajari, N.
登録日2007-05-11
公開日2007-06-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization.
J.Biol.Chem., 61, 2007
1KGX
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Three Dimensional Structure Analysis of the R195Q Variant of Human Pancreatic Alpha Amylase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ...
著者Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G.
登録日2001-11-28
公開日2002-01-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase.
Biochemistry, 41, 2002
1RP8
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Crystal structure of barley alpha-amylase isozyme 1 (amy1) inactive mutant d180a in complex with maltoheptaose
分子名称: Alpha-amylase type 1 isozyme, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者Robert, X, Haser, R, Aghajari, N.
登録日2003-12-03
公開日2005-06-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Oligosaccharide Binding to Barley {alpha}-Amylase 1
J.Biol.Chem., 280, 2005
1EO5
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Bacillus circulans strain 251 cyclodextrin glycosyltransferase in complex with maltoheptaose
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, PROTEIN (CYCLODEXTRIN GLYCOSYLTRANSFERASE), ...
著者Uitdehaag, J.C.M, Dijkstra, B.W.
登録日2000-03-22
公開日2000-11-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of maltohexaose and maltoheptaose bound at the donor sites of cyclodextrin glycosyltransferase give insight into the mechanisms of transglycosylation activity and cyclodextrin size specificity.
Biochemistry, 39, 2000
1MFV
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Probing the role of a mobile loop in human slaivary amylase: Structural studies on the loop-deleted enzyme
分子名称: 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, ...
著者Ramasubbu, N, Ragunath, C, Mishra, P.J.
登録日2002-08-13
公開日2002-11-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the role of a mobile loop in substrate binding and enzyme activity of human salivary amylase.
J.Mol.Biol., 325, 2003
1MFU
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Probing the role of a mobile loop in human salivary amylase: Structural studies on the loop-deleted mutant
分子名称: 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, ...
著者Ramasubbu, N, Ragunath, C, Mishra, P.J.
登録日2002-08-13
公開日2002-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the role of a mobile loop in substrate binding and enzyme activity of human salivary amylase.
J.Mol.Biol., 325, 2003
5N7J
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Crystal structure of Neisseria polysaccharea amylosucrase mutant efficient for the synthesis of controlled size maltooligosaccharides
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Amylosucrase, PENTAETHYLENE GLYCOL, ...
著者Verges, A, Tranier, S.
登録日2017-02-20
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Engineering of anp efficient mutant of Neisseria polysaccharea amylosucrase for the synthesis of controlled size maltooligosaccharides.
Carbohydr Polym, 173, 2017

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