PDB: 46188 件ウェブページステータス検索Chemie searchBIRD

---

4QP2	Crystal Structure of ERKs in complex with 5-chlorobenzo[d]oxazol-2-amine 分子名称: 5-chloro-1,3-benzoxazol-2-amine, IMIDAZOLE, Mitogen-activated protein kinase 1 著者 Yin, J, Wang, W. 登録日 2014-06-22 公開日 2015-09-23 最終更新日 2015-12-16 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
4L55	X-ray structure of the adduct between bovine pancreatic ribonuclease and AziRu 分子名称: RUTHENIUM ION, Ribonuclease pancreatic 著者 Vergara, A, Russo Krauss, I, Merlino, A. 登録日 2013-06-10 公開日 2014-01-29 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Investigating the ruthenium metalation of proteins: X-ray structure and Raman microspectroscopy of the complex between RNase A and AziRu. Inorg.Chem., 52, 2013
4QP8	Crystal Structure of ERK2 in complex with 2-(1H-pyrazol-4-yl)-7-(pyridin-3-yl)-5H-pyrrolo[2,3-b]pyrazine 分子名称: 2-(1H-pyrazol-4-yl)-7-(pyridin-3-yl)-5H-pyrrolo[2,3-b]pyrazine, Mitogen-activated protein kinase 1 著者 Yin, J, Wang, W. 登録日 2014-06-22 公開日 2015-09-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.446 Å) 主引用文献 Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
4GT3	ATP-bound form of the ERK2 kinase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Pozharski, E, Zhang, J, Shapiro, P. 登録日 2012-08-28 公開日 2012-09-12 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 ATP-bound form of the ERK2 kinase TO BE PUBLISHED
2ERK	PHOSPHORYLATED MAP KINASE ERK2 分子名称: EXTRACELLULAR SIGNAL-REGULATED KINASE 2 著者 Canagarajah, B.J, Goldsmith, E.J. 登録日 1997-06-26 公開日 1998-07-01 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Activation mechanism of the MAP kinase ERK2 by dual phosphorylation. Cell(Cambridge,Mass.), 90, 1997
4QPG	Crystal structure of empty hepatitis A virus 分子名称: CHLORIDE ION, Capsid protein VP0, Capsid protein VP1, ... 著者 Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. 登録日 2014-06-23 公開日 2014-10-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Hepatitis A virus and the origins of picornaviruses. Nature, 517, 2015
2KJ9	NMR structure of IntB phage-integrase-like protein fragment 90-199 from Erwinia carotova subsp. atroseptica: Northeast Structural Genomics Consortium target EwR217E 分子名称: Integrase 著者 Cort, J.R, Ramelot, T.A, Wang, D, Ciccosanti, C, Janjua, H, Nair, R, Rost, B, Swapna, G, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) 登録日 2009-05-25 公開日 2009-07-07 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 NMR structure of IntB phage-integrase-like protein fragment 90-199 from Erwinia carotova subsp. atroseptica To be Published
3JPV	Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a pyrrolo[2,3-a]carbazole ligand 分子名称: 1,10-dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde, Peptide (PIMTIDE) ARKRRRHPSGPPTA, Proto-oncogene serine/threonine-protein kinase Pim-1 著者 Filippakopoulos, P, Bullock, A.N, Fedorov, O, Akue-Gedu, R, Rossignol, E, Azzaro, S, Bain, J, Cohen, P, Prudhomme, M, Moreau, P, Amizon, F, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2009-09-04 公開日 2009-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new pim kinase inhibitors. J.Med.Chem., 52, 2009
2NRT	Crystal structure of the C-terminal half of UvrC 分子名称: CHLORIDE ION, UvrABC system protein C 著者 Karakas, E, Truglio, J.J, Kisker, C. 登録日 2006-11-02 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad. Embo J., 26, 2007
2ZP8	The Nature of the TRAP:Anti-TRAP complex 分子名称: TRYPTOPHAN, Transcription attenuation protein mtrB, Tryptophan RNA-binding attenuator protein-inhibitory protein, ... 著者 Watanabe, M, Heddle, J.G, Unzai, S, Akashi, S, Park, S.Y, Tame, J.R.H. 登録日 2008-07-08 公開日 2009-02-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The nature of the TRAP-Anti-TRAP complex. Proc.Natl.Acad.Sci.USA, 106, 2009
4LFX	X-ray structure of the adduct between hen egg white lysozyme and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers 分子名称: CHLORIDE ION, GOLD ION, Lysozyme C, ... 著者 Vergara, A, Merlino, A. 登録日 2013-06-27 公開日 2013-10-02 最終更新日 2013-10-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The mode of action of anticancer gold-based drugs: a structural perspective. Chem.Commun.(Camb.), 49, 2013
4LGB	ABA-mimicking ligand N-(1-METHYL-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-6-YL)-1-(4-METHYLPHENYL)METHANESULFONAMIDE in complex with ABA receptor PYL2 and PP2C HAB1 分子名称: Abscisic acid receptor PYL2, MAGNESIUM ION, N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-1-(4-methylphenyl)methanesulfonamide, ... 著者 Zhou, X.E, Gao, M, Liu, X, Zhang, Y, Xue, X, Melcher, K, Gao, P, Wang, F, Zeng, L, Zhao, Y, Zhao, Y, Deng, P, Zhong, D, Zhu, J.-K, Xu, Y, Xu, H.E. 登録日 2013-06-27 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants. Cell Res., 23, 2013
6ZTQ	Cryo-EM structure of respiratory complex I from Mus musculus inhibited by piericidin A at 3.0 A 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Bridges, H.R, Blaza, J.N, Agip, A.N.A, Hirst, J. 登録日 2020-07-20 公開日 2020-10-21 最終更新日 2020-10-28 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of inhibitor-bound mammalian complex I. Nat Commun, 11, 2020
4LFP	X-ray structure of the adduct between hen egg white lysozyme and a homoleptic gold(I) complex with the saccharynate ligand 分子名称: CHLORIDE ION, GOLD ION, Lysozyme C, ... 著者 Vergara, A, Merlino, A. 登録日 2013-06-27 公開日 2013-10-02 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 The mode of action of anticancer gold-based drugs: a structural perspective. Chem.Commun.(Camb.), 49, 2013
4LG5	ABA-mimicking ligand QUINABACTIN in complex with ABA receptor PYL2 and PP2C HAB1 分子名称: Abscisic acid receptor PYL2, MAGNESIUM ION, Protein phosphatase 2C 16, ... 著者 Zhou, X.E, Gao, M, Liu, X, Zhang, Y, Xue, X, Melcher, K, Gao, P, Wang, F, Zeng, L, Zhao, Y, Zhao, Y, Deng, P, Zhong, D, Zhu, J.-K, Xu, Y, Xu, H.E. 登録日 2013-06-27 公開日 2013-08-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants. Cell Res., 23, 2013
4LGA	ABA-mimicking ligand N-(2-OXO-1-PROPYL-1,2,3,4-TETRAHYDROQUINOLIN-6-YL)-1-PHENYLMETHANESULFONAMIDE in complex with ABA receptor PYL2 and PP2C HAB1 分子名称: Abscisic acid receptor PYL2, MAGNESIUM ION, N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)-1-phenylmethanesulfonamide, ... 著者 Zhou, X.E, Gao, M, Liu, X, Zhang, Y, Xue, X, Melcher, K, Gao, P, Wang, F, Zeng, L, Zhao, Y, Zhao, Y, Deng, P, Zhong, D, Zhu, J.-K, Xu, Y, Xu, H.E. 登録日 2013-06-27 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants. Cell Res., 23, 2013
3JXW	Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors 分子名称: 8-[(E)-2-cyclopropylethenyl]-2-[(dimethylamino)methyl][1]benzothieno[3,2-d]pyrimidin-4(3H)-one, Proto-oncogene serine/threonine-protein kinase Pim-1 著者 Stoll, V.S. 登録日 2009-09-21 公開日 2009-11-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors TO BE PUBLISHED
4GVA	ADP-bound form of the ERK2 kinase 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Mitogen-activated protein kinase 1 著者 Pozharski, E, Zhang, J, Shapiro, P. 登録日 2012-08-30 公開日 2012-09-12 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 ADP-bound form of the ERK2 kinase TO BE PUBLISHED
4LKM	Crystal structure of Plk1 Polo-box domain in complex with PL-74 分子名称: GLYCEROL, PL-74, SULFATE ION, ... 著者 Lee, W.C, Song, J.H, Kim, H.Y. 登録日 2013-07-08 公開日 2013-12-11 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Exploring the binding nature of pyrrolidine pocket-dependent interactions in the polo-box domain of polo-like kinase 1 Plos One, 8, 2013
2ZCZ	Crystal structures and thermostability of mutant TRAP3 A7 (ENGINEERED TRAP) 分子名称: TRYPTOPHAN, Transcription attenuation protein mtrB 著者 Watanabe, M, Mishima, Y, Yamashita, I, Park, S.Y, Tame, J.R.H, Heddle, J.G. 登録日 2007-11-15 公開日 2008-04-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Intersubunit linker length as a modifier of protein stability: crystal structures and thermostability of mutant TRAP. Protein Sci., 17, 2008
8B7F	Nuclease from C. glutamicum 分子名称: Ubiquitin-like protein SMT3,MksG 著者 Wehenkel, A, Ben Assaya, M, Haouz, A. 登録日 2022-09-29 公開日 2023-03-29 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (4.6 Å) 主引用文献 The MksG nuclease is the executing part of the bacterial plasmid defense system MksBEFG. Nucleic Acids Res., 51, 2023
3JBO	Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to P/E-tRNA 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ... 著者 Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J. 登録日 2015-09-16 公開日 2015-10-14 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Res., 43, 2015
3DJI	Crystal Structure of Macrophage Migration Inhibitory Factor Bound to an Acetaminophen Dimer Derived from NAPQI 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, N,N'-(6,6'-dihydroxybiphenyl-3,3'-diyl)diacetamide 著者 Crichlow, G.V, Lolis, E. 登録日 2008-06-23 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions. Biochemistry, 48, 2009
3JV0	Crystal structure of a mutant of RelB dimerization domain(M6) 分子名称: Transcription factor RelB 著者 Vu, D, Huang, D.B, Ghosh, G. 登録日 2009-09-15 公開日 2010-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Instability of the RelB dimerization domain is functionally importent To be Published
3JBN	Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to P-tRNA 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ... 著者 Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J. 登録日 2015-09-16 公開日 2015-10-14 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Res., 43, 2015

<1091109210931094109510961097109810991100110111021103110411051106>