PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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7HAQ	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13428 分子名称: 2-phenyl-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HBH	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13518 分子名称: (5-tert-butylthiophen-2-yl)(pyrrolidin-1-yl)methanone, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HB5	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13078 分子名称: Heat shock protein HSP 90-alpha, ~{N}-(4-chlorophenyl)methanesulfonamide 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
6VEI	Crystal Structure of Human Cytosolic Isocitrate Dehydrogenase (IDH1) R132H Mutant in Complex with NADPH and AG-881 (Vorasidenib) Inhibitor 分子名称: 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diol, 6-(6-chloropyridin-2-yl)-N2,N4-bis[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine, ACETATE ION, ... 著者 Padyana, A, Jin, L. 登録日 2020-01-02 公開日 2020-02-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma. Acs Med.Chem.Lett., 11, 2020
7HBT	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with PS-3621 分子名称: Heat shock protein HSP 90-alpha, [3-(4-methylphenyl)-1H-pyrazol-1-yl]acetic acid 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HBZ	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with 6R-0009 分子名称: (4R)-5-chloro-3-ethyl[1,2,4]triazolo[4,3-a]pyridine, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HBP	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13188 分子名称: Heat shock protein HSP 90-alpha, N-(3,4-difluorophenyl)cyclobutanecarboxamide 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HA9	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13551 分子名称: Heat shock protein HSP 90-alpha, N-[(1R,2S,4R)-bicyclo[2.2.1]heptan-2-yl]-N'-[(2S)-1-hydroxybutan-2-yl]thiourea 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7H9L	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr14229 分子名称: (1s,5s)-bicyclo[3.3.1]nonane-1-carboxamide, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7H9T	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12599 分子名称: (5-methyl-1-phenyl-1H-pyrazol-4-yl)methanol, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
6CII	Crystal structure of Chlamydomonas reinhardtii THB1 in the cyanomet state 分子名称: CYANIDE ION, Chlamydomonas reinhardtii THB1, PROTOPORPHYRIN IX CONTAINING FE 著者 Martinez, J.E, Schlessman, J.L, Lecomte, J.T.J. 登録日 2018-02-23 公開日 2018-04-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Control of distal lysine coordination in a monomeric hemoglobin: A role for heme peripheral interactions J.Inorg.Biochem., 219, 2021
7HA3	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr14259 分子名称: 3-ethyl-2-sulfanylidene-1,3-thiazolidin-4-one, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
4PSX	Crystal structure of histone acetyltransferase complex 分子名称: COENZYME A, Histone H3, Histone H4, ... 著者 Yang, M, Li, Y. 登録日 2014-03-08 公開日 2014-07-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.509 Å) 主引用文献 Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex Genes Dev., 28, 2014
7HAW	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12961 分子名称: Heat shock protein HSP 90-alpha, N-(2,4-difluorophenyl)-N'-methylthiourea 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HBS	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with 10X-0806 分子名称: (5P)-2-chloro-5-(1,3-oxazol-5-yl)pyridine, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HAR	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12616 分子名称: 4-(morpholin-4-yl)benzonitrile, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HB1	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12936 分子名称: (6-phenoxypyridin-3-yl)methanol, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
6CKP	Crystal structure of a thioredoxin domain 2 from Brucella melitensis at 1.15 Angstrom resolution 分子名称: Thioredoxin 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-02-28 公開日 2018-04-04 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Crystal structure of a thioredoxin domain 2 from Brucella melitensis at 1.15 Angstrom resolution To be Published
7HBF	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12938 分子名称: Heat shock protein HSP 90-alpha, {3-[(pyridin-2-yl)oxy]phenyl}methanol 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HAZ	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12919 分子名称: (2-phenoxyphenyl)methanol, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HBJ	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13498 分子名称: 6-(4-chloro-3-methylphenoxy)pyridin-3-amine, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HC2	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with 2X-5009 分子名称: Heat shock protein HSP 90-alpha, N-(pyridin-4-yl)cyclopropanecarboxamide 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7H9Q	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13944 分子名称: 5-fluoro-2-methylbenzamide, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
1YSM	NMR Structure of N-terminal domain (Residues 1-77) of Siah-Interacting Protein. 分子名称: Calcyclin-binding protein 著者 Bhattacharya, S, Lee, Y.T, Michowski, W, Jastrzebska, B, Filipek, A, Kuznicki, J, Chazin, W.J. 登録日 2005-02-08 公開日 2005-07-26 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The Modular Structure of SIP Facilitates Its Role in Stabilizing Multiprotein Assemblies. Biochemistry, 44, 2005
7H9U	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12864 分子名称: 5-chloranylthiophene-2-sulfonamide, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025

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