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7X74
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BU of 7x74 by Molmil
Cryo-EM structure of Streptomyces coelicolor transcription initial complex with two Zur dimers.
分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Yang, X, Zheng, J.
登録日2022-03-09
公開日2022-08-03
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Nucleic Acids Res., 50, 2022
3ATP
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BU of 3atp by Molmil
Structure of the ligand binding domain of the bacterial serine chemoreceptor Tsr with ligand
分子名称: Methyl-accepting chemotaxis protein I, SERINE
著者Tajima, H, Sakuma, M, Homma, K, Kawagishi, I, Imada, K.
登録日2011-01-07
公開日2011-10-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ligand specificity determined by differentially arranged common ligand-binding residues in bacterial amino acid chemoreceptors Tsr and Tar.
J.Biol.Chem., 286, 2011
6GE3
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BU of 6ge3 by Molmil
X-ray structure of TEAD4 (wildtype) complexed with YAP (wildtype): The role of residual flexibility and water molecules in the adaptation of a bound intrinsically disordered protein to mutations at a binding interface
分子名称: GLYCEROL, MYRISTIC ACID, Transcriptional coactivator YAP1, ...
著者Kallen, J.
登録日2018-04-25
公開日2018-09-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface.
Protein Sci., 27, 2018
7X75
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BU of 7x75 by Molmil
Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with three Zur dimers
分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Yang, X, Zheng, J.
登録日2022-03-09
公開日2022-08-03
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Nucleic Acids Res., 50, 2022
3HUG
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BU of 3hug by Molmil
Crystal structure of Mycobacterium tuberculosis anti-sigma factor RslA in complex with -35 promoter binding domain of sigL
分子名称: PROBABLE CONSERVED MEMBRANE PROTEIN, RNA polymerase sigma factor, SULFATE ION, ...
著者Thakur, K.G, Gopal, B.
登録日2009-06-14
公開日2010-03-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural and biochemical bases for the redox sensitivity of Mycobacterium tuberculosis RslA
J.Mol.Biol., 397, 2010
4IW1
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BU of 4iw1 by Molmil
HSA-fructose complex
分子名称: D-fructose, PHOSPHATE ION, Serum albumin, ...
著者Wang, Y, Yu, H, Shi, X, Huang, M.
登録日2013-01-23
公開日2013-04-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
1ZMZ
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BU of 1zmz by Molmil
Solution structure of the N-terminal domain (M1-S98) of human centrin 2
分子名称: Centrin-2
著者Yang, A, Miron, S, Duchambon, P, Assairi, L, Blouquit, Y, Craescu, C.T.
登録日2005-05-11
公開日2006-04-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The N-terminal domain of human centrin 2 has a closed structure, binds calcium with a very low affinity, and plays a role in the protein self-assembly
Biochemistry, 45, 2006
4K76
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BU of 4k76 by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36-TRL (ANSRWPTTRL)
分子名称: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36-TRL peptide
著者Amacher, J.F, Madden, D.R.
登録日2013-04-16
公開日2014-02-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
1KQJ
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BU of 1kqj by Molmil
Crystal Structure of a Mutant of MutY Catalytic Domain
分子名称: A/G-SPECIFIC ADENINE GLYCOSYLASE, GLYCEROL, IRON/SULFUR CLUSTER, ...
著者Messick, T.E, Chmiel, N.H, Golinelli, M.P, David, S.S, Joshua-Tor, L.
登録日2002-01-06
公開日2002-04-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster.
Biochemistry, 41, 2002
4Q2N
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BU of 4q2n by Molmil
INADL PDZ3 in Complex with a Phage-Derived Peptide
分子名称: 1,2-ETHANEDIOL, InaD-like protein
著者Appleton, B.A, Wiesmann, C.
登録日2014-04-09
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A structural portrait of the PDZ domain family.
J.Mol.Biol., 426, 2014
7BMC
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BU of 7bmc by Molmil
Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide and stabilizing Fusicoccin A
分子名称: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ...
著者Centorrino, F, Andlovic, B, Ottmann, C.
登録日2021-01-19
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3.
Acs Chem.Biol., 17, 2022
1CTW
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BU of 1ctw by Molmil
T4 LYSOZYME MUTANT I78A
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
著者Gassner, N.C, Baase, W.A, Lindstrom, J.D, Lu, J, Matthews, B.W.
登録日1999-08-20
公開日1999-11-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding.
Biochemistry, 38, 1999
1CU5
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BU of 1cu5 by Molmil
T4 LYSOZYME MUTANT L91M
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
著者Gassner, N.C, Baase, W.A, Lindstrom, J.D, Lu, J, Matthews, B.W.
登録日1999-08-20
公開日1999-11-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding.
Biochemistry, 38, 1999
1CV6
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BU of 1cv6 by Molmil
T4 LYSOZYME MUTANT V149M
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
著者Gassner, N.C, Baase, W.A, Lindstrom, J, Lu, J, Matthews, B.W.
登録日1999-08-22
公開日1999-11-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding.
Biochemistry, 38, 1999
7BIA
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BU of 7bia by Molmil
Crystal structure of human GSTP1 bound to iberin
分子名称: 1-isothiocyanato-3-methylsulfinyl-propane, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, ...
著者Schwartz, M, Neiers, F.
登録日2021-01-12
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Role of human salivary enzymes in bitter taste perception.
Food Chem, 386, 2022
4K6Y
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BU of 4k6y by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36-Q (ANSRWQTSII)
分子名称: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36-Q peptide
著者Amacher, J.F, Madden, D.R.
登録日2013-04-16
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
1ZA6
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BU of 1za6 by Molmil
The structure of an antitumor CH2-domain-deleted humanized antibody
分子名称: IGG Heavy chain, IGG Light chain
著者Larson, S.B, Day, J.S, Glaser, S, Braslawsky, G, McPherson, A.
登録日2005-04-05
公開日2005-05-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of an Antitumor C(H)2-domain-deleted Humanized Antibody.
J.Mol.Biol., 348, 2005
4J1R
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BU of 4j1r by Molmil
Crystal Structure of GSK3b in complex with inhibitor 15R
分子名称: (2R)-2-(1H-indol-3-ylmethyl)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, Glycogen synthase kinase-3 beta, PHOSPHATE ION, ...
著者Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2013-02-01
公開日2013-03-20
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor
To be Published
2EAX
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BU of 2eax by Molmil
Crystal structure of human PGRP-IBETAC in complex with glycosamyl muramyl pentapeptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-methyl 2-acetamido-3-O-[(1R)-1-carboxyethyl]-2-deoxy-beta-D-glucopyranoside, GLYCOSAMYL MURAMYL PENTAPEPTIDE, Peptidoglycan recognition protein-I-beta
著者Cho, S.
登録日2007-02-03
公開日2007-10-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins
Proc.Natl.Acad.Sci.Usa, 104, 2007
4Q8G
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BU of 4q8g by Molmil
Structure of the Saccharomyces cerevisiae PAN2 pseudoubiquitin-hydrolase
分子名称: PAB-dependent poly(A)-specific ribonuclease subunit PAN2, ZINC ION
著者Schaefer, I.B, Conti, E.
登録日2014-04-27
公開日2014-06-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Nat.Struct.Mol.Biol., 21, 2014
1D2W
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BU of 1d2w by Molmil
N-TERMINAL DOMAIN CORE METHIONINE MUTATION
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
著者Gassner, N.C, Matthews, B.W.
登録日1999-09-28
公開日1999-10-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Use of differentially substituted selenomethionine proteins in X-ray structure determination.
Acta Crystallogr.,Sect.D, 55, 1999
1CU2
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BU of 1cu2 by Molmil
T4 LYSOZYME MUTANT L84M
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
著者Gassner, N.C, Baase, W.A, Lindstrom, J.D, Lu, J, Matthews, B.W.
登録日1999-08-20
公開日1999-11-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding.
Biochemistry, 38, 1999
1D3G
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BU of 1d3g by Molmil
HUMAN DIHYDROOROTATE DEHYDROGENASE COMPLEXED WITH BREQUINAR ANALOG
分子名称: 2-BIPHENYL-4-YL-6-FLUORO-3-METHYL-QUINOLINE-4-CARBOXYLIC ACID, ACETATE ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, ...
著者Liu, S, Neidhardt, E.A, Grossman, T.H, Ocain, T, Clardy, J.
登録日1999-09-29
公開日2000-09-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents.
Structure Fold.Des., 8, 2000
7BIC
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BU of 7bic by Molmil
Crystal structure of human GSTA1-1 bound to allyl-isothiocyanate
分子名称: Glutathione S-transferase A1, N-prop-2-en-1-ylthioformamide
著者Schwartz, M, Neiers, F.
登録日2021-01-12
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Role of human salivary enzymes in bitter taste perception.
Food Chem, 386, 2022
1CHK
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BU of 1chk by Molmil
STREPTOMYCES N174 CHITOSANASE PH5.5 298K
分子名称: CHITOSANASE
著者Marcotte, E.M, Robertus, J.D.
登録日1995-06-12
公開日1996-07-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-ray structure of an anti-fungal chitosanase from streptomyces N174.
Nat.Struct.Biol., 3, 1996

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