PDB: 35756 件ウェブページステータス検索Chemie searchBIRD

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7BIW	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-187 分子名称: 14-3-3 protein sigma, 4-(3,4-dihydro-2~{H}-quinoxalin-1-ylsulfonyl)benzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-01-13 公開日 2021-09-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
1FGO	LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q495A MUTANT 分子名称: FE (III) ION, SEED LIPOXYGENASE-1 著者 Tomchick, D.R, Minor, W, Holman, T. 登録日 2000-07-28 公開日 2001-07-04 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1. Biochemistry, 40, 2001
7BJB	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-044 分子名称: 14-3-3 protein sigma, 4-(4-methylphenyl)sulfonylmorpholine, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-01-14 公開日 2021-09-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
2ANZ	cytochrome c peroxidase in complex with 2,6-diaminopyridine 分子名称: Cytochrome c peroxidase, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Brenk, R, Vetter, S.W, Boyce, S.E, Goodin, D.B, Shoichet, B.K. 登録日 2005-08-11 公開日 2006-04-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Probing molecular docking in a charged model binding site. J.Mol.Biol., 357, 2006
1FAH	STRUCTURE OF CYTOCHROME P450 分子名称: CYTOCHROME P450 BM-3, PROTOPORPHYRIN IX CONTAINING FE 著者 Li, H.Y, Poulos, T.L. 登録日 1996-08-01 公開日 1997-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The role of Thr268 in oxygen activation of cytochrome P450BM-3. Biochemistry, 34, 1995
7R70	Crystal Structure of the UbArk2C fusion protein 分子名称: GLYCEROL, Ubiquitin,E3 ubiquitin-protein ligase RNF165, ZINC ION 著者 Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L. 登録日 2021-06-24 公開日 2022-03-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.499 Å) 主引用文献 Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C. Nat Commun, 13, 2022
1XS9	A MODEL OF THE TERNARY COMPLEX FORMED BETWEEN MARA, THE ALPHA-CTD OF RNA POLYMERASE AND DNA 分子名称: 5'-D(P*AP*TP*GP*CP*CP*AP*CP*GP*TP*TP*TP*TP*GP*CP*TP*AP*AP*AP*TP*C)-3', 5'-D(P*GP*AP*TP*TP*TP*AP*GP*CP*AP*AP*AP*AP*CP*GP*TP*GP*GP*CP*AP*T)-3', DNA-directed RNA polymerase alpha chain, ... 著者 Dangi, B, Gronenborn, A.M, Rosner, J.L, Martin, R.G. 登録日 2004-10-18 公開日 2004-10-26 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Versatility of the carboxy-terminal domain of the alpha subunit of RNA polymerase in transcriptional activation: use of the DNA contact site as a protein contact site for MarA. Mol.Microbiol., 54, 2004
2AS3	cytochrome c peroxidase in complex with phenol 分子名称: Cytochrome c peroxidase, mitochondrial, PHENOL, ... 著者 Brenk, R, Vetter, S.W, Boyce, S.E, Goodin, D.B, Shoichet, B.K. 登録日 2005-08-22 公開日 2006-04-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Probing molecular docking in a charged model binding site. J.Mol.Biol., 357, 2006
1FLG	CRYSTAL STRUCTURE OF THE QUINOPROTEIN ETHANOL DEHYDROGENASE FROM PSEUDOMONAS AERUGINOSA 分子名称: CALCIUM ION, PROTEIN (QUINOPROTEIN ETHANOL DEHYDROGENASE), PYRROLOQUINOLINE QUINONE 著者 Keitel, T, Diehl, A, Knaute, T, Stezowski, J.J, Hohne, W, Gorisch, H. 登録日 2000-08-14 公開日 2000-08-30 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 X-ray structure of the quinoprotein ethanol dehydrogenase from Pseudomonas aeruginosa: basis of substrate specificity. J.Mol.Biol., 297, 2000
1JAY	Structure of Coenzyme F420H2:NADP+ Oxidoreductase (FNO) with its substrates bound 分子名称: COENZYME F420, Coenzyme F420H2:NADP+ Oxidoreductase (FNO), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Warkentin, E, Mamat, B, Thauer, R, Ermler, U, Shima, S. 登録日 2001-06-01 公開日 2001-12-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structures of F420H2:NADP+ oxidoreductase with and without its substrates bound. EMBO J., 20, 2001
7R71	Crystal Structure of the UbArk2C-UbcH5b~Ub complex 分子名称: Ubiquitin, Ubiquitin,E3 ubiquitin-protein ligase RNF165, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L. 登録日 2021-06-24 公開日 2022-03-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C. Nat Commun, 13, 2022
2ATW	Structure of a Mycobacterium tuberculosis NusA-RNA complex 分子名称: Transcription elongation protein nusA, ribosomal RNA (5'- AGAACUCAAUAG -3') 著者 Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A. 登録日 2005-08-26 公開日 2005-10-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of a Mycobacterium tuberculosis NusA-RNA complex. Embo J., 24, 2005
4MT7	Crystal structure of collybistin I 分子名称: Rho guanine nucleotide exchange factor 9 著者 Schneeberger, D, Schindelin, H. 登録日 2013-09-19 公開日 2014-08-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 A conformational switch in collybistin determines the differentiation of inhibitory postsynapses. Embo J., 33, 2014
1JDJ	CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA GLYCEROL-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH 2-FLUORO-6-CHLOROPURINE 分子名称: 6-CHLORO-2-FLUOROPURINE, GLYCEROL-3-PHOSPHATE DEHYDROGENASE, PENTADECANE 著者 Suresh, S, Wisedchaisri, G, Kennedy, K.J, Verlinde, C.L.M.J, Gelb, M.H, Hol, W.G.J. 登録日 2001-06-14 公開日 2002-06-14 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase. Chem.Biol., 9, 2002
3JTL	Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator 分子名称: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta 著者 Stadtmueller, B.M, Whitby, F.G, Hill, C.P. 登録日 2009-09-12 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Models for Interactions between the 20S proteasome and its PAN/19S activators. J.Biol.Chem., 285, 2010
7VR0	Human Serum Albumin 分子名称: Serum albumin 著者 Xiang, W, Yue, Z.L, Su, J.Y. 登録日 2021-10-21 公開日 2022-10-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Human Serum Albumin To Be Published
4MVX	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-phenylurea (Chem 1356) 分子名称: 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-phenylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
4MWC	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[(2-methyl-1-benzothiophen-3-yl)methyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1540) 分子名称: 1-(3-{[(2-methyl-1-benzothiophen-3-yl)methyl]amino}propyl)-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.649 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
1GB2	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-06-26 公開日 2000-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
4MVY	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(3-hydroxyphenyl)urea (Chem 1387) 分子名称: 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(3-hydroxyphenyl)urea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.314 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
1GB9	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-06-26 公開日 2000-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
3ANG	Crystal structure of Thermus thermophilus FadR in complex with E. coli-derived dodecyl-CoA 分子名称: DODECYL-COA, Transcriptional repressor, TetR family 著者 Agari, Y, Sakamoto, K, Agari, K, Kuramitsu, S, Shinkai, A. 登録日 2010-09-01 公開日 2011-03-09 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 TetR-family transcriptional repressor Thermus thermophilus FadR controls fatty acid degradation. Microbiology, 157, 2011
1FZ2	METHANE MONOOXYGENASE HYDROXYLASE, FORM II MIXED-VALENT GENERATED BY CRYSTAL SOAKING 分子名称: CALCIUM ION, FE (II) ION, METHANE MONOOXYGENASE COMPONENT A, ... 著者 Whittington, D.A, Lippard, S.J. 登録日 2000-10-03 公開日 2001-02-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath) demonstrating geometrical variability at the dinuclear iron active site. J.Am.Chem.Soc., 123, 2001
4RQ7	Human DNA Polymerase Beta With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine (8-oxoG)and dATP soaked with MgCl2 for 1hr 分子名称: ACETATE ION, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Vyas, R, Reed, A.J, Suo, Z. 登録日 2014-10-31 公開日 2015-04-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography. J.Am.Chem.Soc., 137, 2015
3A8K	Crystal Structure of ETD97N-EHred complex 分子名称: Aminomethyltransferase, Glycine cleavage system H protein 著者 Okamura-Ikeda, K, Hosaka, H. 登録日 2009-10-06 公開日 2010-04-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of aminomethyltransferase in complex with dihydrolipoyl-H-protein of the glycine cleavage system: implications for recognition of lipoyl protein substrate, disease-related mutations, and reaction mechanism J.Biol.Chem., 285, 2010

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