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5ZF4
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Structure of human dihydroorotate dehydrogenase in complex with 275-10-COOMe
分子名称: ACETATE ION, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
著者Miyazaki, Y, Inaoka, K.D, Shiba, T, Saimoto, H, Amalia, E, Kido, Y, Sakai, C, Nakamura, M, Moore, L.A, Harada, S, Kita, K.
登録日2018-03-02
公開日2018-09-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions.
Front Pharmacol, 9, 2018
2C95
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Structure of adenylate kinase 1 in complex with P1,P4-di(adenosine) tetraphosphate
分子名称: ADENYLATE KINASE 1, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, MALONATE ION
著者Bunkoczi, G, Filippakopoulos, P, Jansson, A, Longman, E, von Delft, F, Edwards, A, Arrowsmith, C, Sundstrom, M, Knapp, S.
登録日2005-12-09
公開日2007-02-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structure of Adenylate Kinase 1 in Complex with P1, P4-Di(Adenosine)Tetraphosphate
To be Published
5ZFA
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Structure of human dihydroorotate dehydrogenase in complex with 287-12-OCOiPr
分子名称: (2E,6E)-8-(3-chloro-5-formyl-2,6-dihydroxy-4-methylphenyl)-3,6-dimethylocta-2,6-dien-1-yl 2-methylpropanoate, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ...
著者Miyazaki, Y, Inaoka, K.D, Shiba, T, Saimoto, H, Amalia, E, Kido, Y, Sakai, C, Nakamura, M, Moore, L.A, Harada, S, Kita, K.
登録日2018-03-02
公開日2018-09-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions.
Front Pharmacol, 9, 2018
1CYQ
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BU of 1cyq by Molmil
INTRON ENCODED HOMING ENDONUCLEASE I-PPOI (H98A)/DNA HOMING SITE COMPLEX
分子名称: 5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3', INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI, MAGNESIUM ION, ...
著者Galburt, E.A, Chevalier, B, Jurica, M.S, Flick, K.E, Stoddard, B.L.
登録日1999-08-31
公開日1999-11-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A novel endonuclease mechanism directly visualized for I-PpoI.
Nat.Struct.Biol., 6, 1999
1JIW
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BU of 1jiw by Molmil
Crystal structure of the APR-APRin complex
分子名称: ALKALINE METALLOPROTEINASE, CALCIUM ION, PROTEINASE INHIBITOR, ...
著者Hege, T, Feltzer, R.E, Gray, R.D, Baumann, U.
登録日2001-07-03
公開日2001-08-15
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structure of a complex between Pseudomonas aeruginosa alkaline protease and its cognate inhibitor: inhibition by a zinc-NH2 coordinative bond
J.Biol.Chem., 276, 2001
3CM2
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BU of 3cm2 by Molmil
Crystal Structure of XIAP BIR3 domain in complex with a Smac-mimetic compound, Smac010
分子名称: (3S,6S,7R,9aS)-6-{[(2S)-2-aminobutanoyl]amino}-7-(aminomethyl)-N-(diphenylmethyl)-5-oxooctahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide, Baculoviral IAP repeat-containing protein 4, ZINC ION
著者Cossu, F, Mastrangelo, E, Milani, M.
登録日2008-03-20
公開日2008-10-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles.
J.Mol.Biol., 384, 2008
1R7J
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Crystal structure of the DNA-binding protein Sso10a from Sulfolobus solfataricus
分子名称: Conserved hypothetical protein Sso10a
著者Chen, L, Chen, L.R, Zhou, X.E, Wang, Y, Kahsai, M.A, Clark, A.T, Edmondson, S.P, Liu, Z.-J, Rose, J.P, Wang, B.C, Shriver, J.W, Meehan, E.J, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2003-10-21
公開日2004-07-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献The hyperthermophile protein Sso10a is a dimer of winged helix DNA-binding domains linked by an antiparallel coiled coil rod.
J.Mol.Biol., 341, 2004
1C3Q
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BU of 1c3q by Molmil
CRYSTAL STRUCTURE OF NATIVE THIAZOLE KINASE IN THE MONOCLINIC FORM
分子名称: 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, CHLORIDE ION, Hydroxyethylthiazole kinase
著者Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E.
登録日1999-07-28
公開日1999-08-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Biochemistry, 39, 2000
2V9N
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L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A88F- E192A)
分子名称: CITRIC ACID, GLYCEROL, PHOSPHATE ION, ...
著者Grueninger, D, Schulz, G.E.
登録日2007-08-24
公開日2008-01-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Designed protein-protein association.
Science, 319, 2008
1NUB
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BU of 1nub by Molmil
HELIX C DELETION MUTANT OF BM-40 FS-EC DOMAIN PAIR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BASEMENT MEMBRANE PROTEIN BM-40, CALCIUM ION
著者Hohenester, E, Sasaki, T, Timpl, R.
登録日1997-12-05
公開日1998-12-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin.
EMBO J., 17, 1998
2VN8
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Crystal structure of human Reticulon 4 interacting protein 1 in complex with NADPH
分子名称: CITRIC ACID, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Pike, A.C.W, Guo, K, Elkins, J, Ugochukwu, E, Roos, A.K, Filippakopoulos, P, von Delft, F, Edwards, A, Arrowsmith, C.H, Weigelt, J, Bountra, C, Oppermann, U.
登録日2008-01-31
公開日2008-03-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Human Reticulon 4 Interacting Protein 1 in Complex with Nadph
To be Published
2NRL
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BU of 2nrl by Molmil
Blackfin tuna myoglobin
分子名称: 1,2-ETHANEDIOL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Schreiter, E.R, Rodr guez, M.M, Weichsel, A, Montfort, W.R, Bonaventura, J.
登録日2006-11-02
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (0.91 Å)
主引用文献S-nitrosylation-induced conformational change in blackfin tuna myoglobin.
J.Biol.Chem., 282, 2007
3IS7
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BU of 3is7 by Molmil
Structure of mineralized Bfrb from Pseudomonas aeruginosa to 2.1A Resolution
分子名称: Bacterioferritin, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE
著者Lovell, S, Weeratunga, S.K, Battaile, K.P, Rivera, M.
登録日2009-08-25
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Studies of Bacterioferritin B from Pseudomonas aeruginosa Suggest a Gating Mechanism for Iron Uptake via the Ferroxidase Center
Biochemistry, 49, 2010
2NRV
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BU of 2nrv by Molmil
Crystal structure of the C-terminal half of UvrC
分子名称: SODIUM ION, UvrABC system protein C
著者Karakas, E, Truglio, J.J, Kisker, C.
登録日2006-11-02
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad.
Embo J., 26, 2007
1NVE
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BU of 1nve by Molmil
Crystal structure of 3-dehydroquinate synthase (DHQS) in complex with ZN2+ and NAD
分子名称: 3-DEHYDROQUINATE SYNTHASE, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Nichols, C.E, Ren, J, Lamb, H.K, Hawkins, A.R, Stammers, D.K.
登録日2003-02-03
公開日2003-03-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Ligand-induced Conformational Changes and a Mechanism for Domain Closure in Aspergillus nidulans Dehydroquinate Synthase
J.MOL.BIOL., 327, 2003
8VDR
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BU of 8vdr by Molmil
Cryogenic electron microscopy model of full-length talin without R12 and FABD
分子名称: Green fluorescent protein,Talin-1
著者Izard, T, Rangarajan, E.S.
登録日2023-12-17
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献High-resolution snapshots of talin auto-inhibitory states
To be published
1BLF
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BU of 1blf by Molmil
STRUCTURE OF DIFERRIC BOVINE LACTOFERRIN AT 2.8 ANGSTROMS RESOLUTION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Moore, S.A, Anderson, B.F, Groom, C.R, Haridas, M, Baker, E.N.
登録日1997-08-20
公開日1997-12-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Three-dimensional structure of diferric bovine lactoferrin at 2.8 A resolution.
J.Mol.Biol., 274, 1997
1JBO
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BU of 1jbo by Molmil
The 1.45A Three-Dimensional Structure of c-Phycocyanin from the Thermophylic Cyanobacterium Synechococcus elongatus
分子名称: C-Phycocyanin alpha chain, C-Phycocyanin beta chain, PHYCOCYANOBILIN
著者Nield, J, Rizkallah, P.J, Barber, J, Chayen, N.E.
登録日2002-05-02
公開日2003-03-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The 1.45A three-dimensional structure of C-phycocyanin from the thermophilic cyanobacterium Synechococcus elongatus
J.STRUCT.BIOL., 141, 2003
7JFP
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BU of 7jfp by Molmil
GTP-specific succinyl-CoA synthetase complexed with Mg-GDP, phosphohistidine loop pointing towards nucleotide binding site
分子名称: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Huang, J, Fraser, M.E.
登録日2020-07-17
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase
Acta Crystallogr.,Sect.D, 77, 2021
3CQF
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Crystal structure of anthrolysin O (ALO)
分子名称: Thiol-activated cytolysin
著者Bourdeau, R.W, Malito, E, Tang, W.J.
登録日2008-04-02
公開日2009-03-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis
J.Biol.Chem., 284, 2009
3MWE
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BU of 3mwe by Molmil
Truncated Human ATP-Citrate Lyase with Tartrate Bound
分子名称: ATP-citrate synthase, L(+)-TARTARIC ACID, MAGNESIUM ION
著者Fraser, M.E, Sun, T.
登録日2010-05-05
公開日2010-06-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography.
J.Biol.Chem., 285, 2010
7JJ0
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GTP-specific succinyl-CoA synthetase complexed with Mg-GMPPCP
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, ...
著者Huang, J, Fraser, M.E.
登録日2020-07-24
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase
Acta Crystallogr.,Sect.D, 77, 2021
2NV4
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Crystal structure of UPF0066 protein AF0241 in complex with S-adenosylmethionine. Northeast Structural Genomics Consortium target GR27
分子名称: ACETATE ION, S-ADENOSYLMETHIONINE, UPF0066 protein AF_0241
著者Kuzin, A.P, Abashidze, M, Seetharaman, J, Vorobiev, S.M, Fang, Y, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2006-11-10
公開日2006-11-21
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Functional insights from structural genomics.
J.Struct.Funct.Genom., 8, 2007
1BSI
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BU of 1bsi by Molmil
HUMAN PANCREATIC ALPHA-AMYLASE FROM PICHIA PASTORIS, GLYCOSYLATED PROTEIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, CALCIUM ION, ...
著者Rydberg, E.H, Sidhu, G, Vo, H.C, Hewitt, J, Cote, H.C.F, Wang, Y, Numao, S, Macgillivray, R.T.A, Overall, C.M, Brayer, G.D, Withers, S.G.
登録日1998-08-28
公開日1999-05-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cloning, mutagenesis, and structural analysis of human pancreatic alpha-amylase expressed in Pichia pastoris.
Protein Sci., 8, 1999
3MTG
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BU of 3mtg by Molmil
Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative adenosylhomocysteinase 2
著者Wisniewska, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schutz, P, Thorsell, A.G, Tresaugues, L, van der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein
TO BE PUBLISHED

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