1UMF
 
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1US8
 | | The Rad50 signature motif: essential to ATP binding and biological function | | 分子名称: | DNA DOUBLE-STRAND BREAK REPAIR RAD50 ATPASE | | 著者 | Moncalian, G, Lengsfeld, B, Bhaskara, V, Hopfner, K.P, Karcher, A, Alden, E, Tainer, J.A, Paull, T.T. | | 登録日 | 2003-11-20 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Rad50 Signature Motif: Essential to ATP Binding and Biological Function
J.Mol.Biol., 335, 2004
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1UX6
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1UX4
 | | Crystal structures of a Formin Homology-2 domain reveal a tethered-dimer architecture | | 分子名称: | BNI1 PROTEIN | | 著者 | Xu, Y, Moseley, J.B, Sagot, I, Poy, F, Pellman, D, Goode, B.L, Eck, M.J. | | 登録日 | 2004-02-19 | | 公開日 | 2004-03-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Crystal Structures of a Formin Homology-2 Domain Reveal a Tethered Dimer Architecture
Cell(Cambridge,Mass.), 116, 2004
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1V0D
 | | Crystal Structure of Caspase-activated DNase (CAD) | | 分子名称: | DNA FRAGMENTATION FACTOR 40 KDA SUBUNIT, LEAD (II) ION, MAGNESIUM ION, ... | | 著者 | Woo, E.-J, Kim, Y.-G, Kim, M.-S, Han, W.-D, Shin, S, Oh, B.-H. | | 登録日 | 2004-03-26 | | 公開日 | 2004-05-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Mechanism for Inactivation and Activation of Cad/Dff40 in the Apoptotic Pathway
Mol.Cell, 14, 2004
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1UZF
 | | Complex of the anti-hypertensive drug captopril an the human testicular angiotensin I-converting enzyme | | 分子名称: | 1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN CONVERTING ENZYME, ... | | 著者 | Natesh, R, Schwager, S.L.U, Evans, H.R, Sturrock, E.D, Acharya, K.R. | | 登録日 | 2004-03-11 | | 公開日 | 2004-07-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Details on the Binding of Antihypertensive Drugs Captopril and Enalaprilat to Human Testicular Angiotensin I-Converting Enzyme
Biochemistry, 43, 2004
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1VC6
 | | Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Product with C75U Mutaion, cleaved in Imidazole and Mg2+ solutions | | 分子名称: | Hepatitis Delta virus ribozyme, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A | | 著者 | Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A. | | 登録日 | 2004-03-04 | | 公開日 | 2004-05-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
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1ULV
 | | Crystal Structure of Glucodextranase Complexed with Acarbose | | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, glucodextranase | | 著者 | Mizuno, M, Tonozuka, T, Suzuki, S, Uotsu-Tomita, R, Kamitori, S, Nishikawa, A, Sakano, Y. | | 登録日 | 2003-09-16 | | 公開日 | 2003-12-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structural insights into substrate specificity and function of glucodextranase
J.Biol.Chem., 279, 2004
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1UMC
 | | branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 with 4-methylpentanoate | | 分子名称: | 2-oxo acid dehydrogenase alpha subunit, 2-oxo acid dehydrogenase beta subunit, 4-METHYL VALERIC ACID, ... | | 著者 | Nakai, T, Nakagawa, N, Maoka, N, Masui, R, Kuramitsu, S, Kamiya, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-09-25 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Ligand-induced Conformational Changes and a Reaction Intermediate in Branched-chain 2-Oxo Acid Dehydrogenase (E1) from Thermus thermophilus HB8, as Revealed by X-ray Crystallography
J.Mol.Biol., 337, 2004
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1UM9
 | | branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 in apo-form | | 分子名称: | 2-oxo acid dehydrogenase alpha subunit, 2-oxo acid dehydrogenase beta subunit, SULFATE ION | | 著者 | Nakai, T, Nakagawa, N, Maoka, N, Masui, R, Kuramitsu, S, Kamiya, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-09-25 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Ligand-induced Conformational Changes and a Reaction Intermediate in Branched-chain 2-Oxo Acid Dehydrogenase (E1) from Thermus thermophilus HB8, as Revealed by X-ray Crystallography
J.Mol.Biol., 337, 2004
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1UPJ
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1UPK
 | | Crystal structure of MO25 in complex with a C-terminal peptide of STRAD | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MO25 PROTEIN, STE-20 RELATED ADAPTOR | | 著者 | Milburn, C.C, Boudeau, J, Deak, M, Alessi, D.R, Van Aalten, D.M.F. | | 登録日 | 2003-10-07 | | 公開日 | 2004-01-22 | | 最終更新日 | 2019-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal Structure of Mo25 Alpha in Complex with the C-Terminus of the Pseudo Kinase Ste-20 Related Adaptor (Strad)
Nat.Struct.Mol.Biol., 11, 2004
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1UR4
 | | The structure of endo-beta-1,4-galactanase from Bacillus licheniformis in complex with two oligosaccharide products. | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, GALACTANASE, ... | | 著者 | Ryttersgaard, C, Le Nours, J, Lo Leggio, L, Jorgensen, C.T, Christensen, L.L.H, Bjornvad, M, Larsen, S. | | 登録日 | 2003-10-24 | | 公開日 | 2004-10-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Structure of Endo-Beta-1,4-Galactanase from Bacillus Licheniformis in Complex with Two Oligosaccharide Products
J.Mol.Biol., 341, 2004
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1UQS
 | | The Crystal Structure of Human CD1b with a Bound Bacterial Glycolipid | | 分子名称: | BETA-2-MICROGLOBULIN, GLUCOSE MONOMYCOLATE, T-CELL SURFACE GLYCOPROTEIN CD1B | | 著者 | Batuwangala, T, Shepherd, D, Gadola, S.D, Gibson, K.J.C, Zaccai, N.R, Besra, G.S, Cerundolo, V, Jones, E.Y. | | 登録日 | 2003-10-16 | | 公開日 | 2003-10-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The crystal structure of human CD1b with a bound bacterial glycolipid.
J Immunol., 172, 2004
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1UTE
 | | PIG PURPLE ACID PHOSPHATASE COMPLEXED WITH PHOSPHATE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ISOPROPYL ALCOHOL, MU-OXO-DIIRON, ... | | 著者 | Guddat, L.W, Mcalpine, A, Hume, D, Hamilton, S, De Jersey, J, Martin, J.L. | | 登録日 | 1999-01-18 | | 公開日 | 1999-10-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of mammalian purple acid phosphatase.
Structure Fold.Des., 7, 1999
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1URD
 | | X-ray structures of the maltose-maltodextrin binding protein of the thermoacidophilic bacterium Alicyclobacillus acidocaldarius provide insight into acid stability of proteins | | 分子名称: | MALTOSE-BINDING PROTEIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Schafer, K, Magnusson, U, Scheffel, F, Schiefner, A, Sandgren, M.O.J, Diederichs, K, Welte, W, Hulsmann, A, Schneider, E, Mowbray, S.L. | | 登録日 | 2003-10-29 | | 公開日 | 2003-12-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | X-Ray Structures of the Maltose-Maltodextrin-Binding Protein of the Thermoacidophilic Bacterium Alicyclobacillus Acidocaldarius Provide Insight Into Acid Stability of Proteins.
J.Mol.Biol., 335, 2004
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1URW
 | | CDK2 IN COMPLEX WITH AN IMIDAZO[1,2-b]PYRIDAZINE | | 分子名称: | 2-[4-(N-(3-DIMETHYLAMINOPROPYL)SULPHAMOYL)ANILINO]-, CELL DIVISION PROTEIN KINASE 2 | | 著者 | Byth, K.F, Cooper, N, Culshaw, J.D, Heaton, D.W, Oakes, S.E, Minshull, C.A, Norman, R.A, Pauptit, R.A, Tucker, J.A, Breed, J, Pannifer, A, Rowsell, S, Stanway, J.J, Valentine, A.L, Thomas, A.P. | | 登録日 | 2003-11-11 | | 公開日 | 2004-04-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Imidazo[1,2-B]Pyridazines: A Potent and Selective Class of Cyclin-Dependent Kinase Inhibitors
Bioorg.Med.Chem.Lett., 14, 2004
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1UT6
 | | Structure of acetylcholinesterase (E.C. 3.1.1.7) complexed with N-9-(1',2',3',4'-Tetrahydroacridinyl)-1,8- diaminooctane at 2.4 angstroms resolution. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, N-9-(1',2',3',4'-TETRAHYDROACRIDINYL)-1,8-DIAMINOOCTANE | | 著者 | Brumshtein, B, Wong, D.M, Greenblatt, H.M, Carlier, P.R, Pang, Y.-P, Silman, I, Sussman, J.L. | | 登録日 | 2003-12-04 | | 公開日 | 2005-04-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Complexes of Alkylene-Linked Tacrine Dimers with Torpedo Californica Acetylcholinesterase: Binding of Bis(5)-Tacrine Produces a Dramatic Rearrangement in the Active-Site Gorge.
J.Med.Chem., 49, 2006
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1UTL
 | | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-PHENYLPROPYLAMINE, CALCIUM ION, ... | | 著者 | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | | 登録日 | 2003-12-09 | | 公開日 | 2004-01-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements
Protein Sci., 13, 2004
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1VBC
 | | POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R77975 | | 分子名称: | (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3 | | 著者 | Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M. | | 登録日 | 1996-01-02 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
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1UZE
 | | Complex of the anti-hypertensive drug enalaprilat and the human testicular angiotensin I-converting enzyme | | 分子名称: | 1-((2S)-2-{[(1S)-1-CARBOXY-3-PHENYLPROPYL]AMINO}PROPANOYL)-L-PROLINE, ANGIOTENSIN CONVERTING ENZYME, CHLORIDE ION, ... | | 著者 | Natesh, R, Schwager, S.L.U, Evans, H.R, Sturrock, E.D, Acharya, K.R. | | 登録日 | 2004-03-11 | | 公開日 | 2004-07-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structural Details on the Binding of Antihypertensive Drugs Captopril and Enalaprilat to Human Testicular Angiotensin I-Converting Enzyme
Biochemistry, 43, 2004
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1UUE
 | | a-SPECTRIN SH3 DOMAIN (V44T, D48G MUTANT) | | 分子名称: | SPECTRIN ALPHA CHAIN | | 著者 | Vega, M.C, Fernandez, A, Wilmanns, M, Serrano, L. | | 登録日 | 2003-12-18 | | 公開日 | 2004-02-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Solvation in Protein Folding Analysis: Combination of Theoretical and Experimental Approaches
Proc.Natl.Acad.Sci.USA, 101, 2004
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1V00
 | | Erythrina cristagalli lectin | | 分子名称: | CALCIUM ION, LECTIN (ECL), MANGANESE (II) ION, ... | | 著者 | Turton, K, Natesh, R, Thiyagarajan, N, Chaddock, J.A, Acharya, K.R. | | 登録日 | 2004-03-21 | | 公開日 | 2004-06-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structures of Erythrina Cristagalli Lectin with Bound N-Linked Oligosaccharide and Lactose
Glycobiology, 14, 2004
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1UV0
 | | Pancreatitis-associated protein 1 from human | | 分子名称: | PANCREATITIS-ASSOCIATED PROTEIN 1, ZINC ION | | 著者 | Abergel, C, Shepard, W, Christal, L. | | 登録日 | 2004-01-12 | | 公開日 | 2004-01-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystallization and preliminary crystallographic study of HIP/PAP, a human C-lectin overexpressed in primary liver cancers.
Acta Crystallogr.,Sect.D, 55, 1999
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1UWY
 | | Crystal structure of human carboxypeptidase M | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE M, ZINC ION | | 著者 | Maskos, K, Reverter, D, Bode, W. | | 登録日 | 2004-02-17 | | 公開日 | 2004-04-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal Structure of Human Carboxypeptidase M, a Membrane-Bound Enzyme that Regulates Peptide Hormone Activity
J.Mol.Biol., 338, 2004
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