PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

---

7BDU	Crystal structure of a Hsp47-collagen peptide complex 分子名称: 21er collagen model peptide, Collagen-binding protein 著者 Abraham, E.T, Gebauer, J.M, Baumann, U. 登録日 2020-12-22 公開日 2021-11-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Collagen's primary structure determines collagen:HSP47 complex stoichiometry. J.Biol.Chem., 297, 2021
2B6A	Crystal structure of HIV-1 reverse transcriptase (RT) in complex with THR-50 分子名称: 1-(2,6-DIFLUOROBENZYL)-2-(2,6-DIFLUOROPHENYL)-4-METHYL-1H-BENZIMIDAZOLE, Reverse transcriptase p51 subunit, Reverse transcriptase p66 subunit 著者 Morningstar, M.L, Roth, T, Smith, M.K, Zajac, M, Watson, K, Buckheit, R.W, Das, K, Zhang, W, Arnold, E, Michejda, C.J. 登録日 2005-09-30 公開日 2005-11-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of HIV-1 reverse transcriptase (RT) in complex with THR-50 TO BE PUBLISHED
2B76	E. coli Quinol fumarate reductase FrdA E49Q mutation 分子名称: CITRATE ANION, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... 著者 Maklashina, E, Iverson, T.M, Sher, Y, Kotlyar, V, Mirza, O, Andrell, J, Hudson, J.M, Armstrong, F.A, Cecchini, G. 登録日 2005-10-03 公開日 2006-02-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Fumarate Reductase and Succinate Oxidase Activity of Escherichia coli Complex II Homologs Are Perturbed Differently by Mutation of the Flavin Binding Domain J.Biol.Chem., 281, 2006
2B0E	EcoRV Restriction Endonuclease/GAAUTC/Ca2+ 分子名称: 5'-D(*AP*AP*AP*GP*AP*AP*(DU)P*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV 著者 Hiller, D.A, Rodriguez, A.M, Perona, J.J. 登録日 2005-09-13 公開日 2005-09-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Non-cognate Enzyme-DNA Complex: Structural and Kinetic Analysis of EcoRV Endonuclease Bound to the EcoRI Recognition Site GAATTC J.Mol.Biol., 354, 2005
6N65	KRAS G-quadruplex G16T mutant. 分子名称: KRAS G-quadruplex G16T mutant, POTASSIUM ION 著者 Schmidberger, J.W, Ou, A, Smith, N.M, Iyer, K.S, Bond, C.S. 登録日 2018-11-25 公開日 2020-04-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 High resolution crystal structure of a KRAS promoter G-quadruplex reveals a dimer with extensive poly-A pi-stacking interactions for small-molecule recognition. Nucleic Acids Res., 48, 2020
7BHE	DARPin_D5/Her3 domain 4 complex, monoclinic crystals 分子名称: ACETATE ION, DARPin_D5, GLYCEROL, ... 著者 Mittl, P.R.E, Radom, F, Pluckthun, A. 登録日 2021-01-11 公開日 2021-11-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.297 Å) 主引用文献 Crystal structures of HER3 extracellular domain 4 in complex with the designed ankyrin-repeat protein D5. Acta Crystallogr.,Sect.F, 77, 2021
2B3Y	Structure of a monoclinic crystal form of human cytosolic aconitase (IRP1) 分子名称: ACETATE ION, FORMIC ACID, GLYCEROL, ... 著者 Dupuy, J, Fontecilla-Camps, J.C, Volbeda, A. 登録日 2005-09-22 公開日 2006-01-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of human iron regulatory protein 1 as cytosolic aconitase Structure, 14, 2006
2AG3	Heterocyclic Peptide Backbone Modification in Gcn4-pLI Based Coiled Coils: Substitution of the K(15)-L(16) amide with a triazole 分子名称: GCN4-pLI 著者 Horne, W.S, Ghadiri, M.R. 登録日 2005-07-26 公開日 2006-08-08 最終更新日 2018-03-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Copper-Catalyzed Azide-Alkyne Cycloaddition as a Non-native Ligation Strategy toward Backbone-Modified Peptides To be Published
2AGL	Crystal structure of the phenylhydrazine adduct of aromatic amine dehydrogenase from Alcaligenes faecalis 分子名称: 1-PHENYLHYDRAZINE, Aromatic amine dehydrogenase 著者 Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. 登録日 2005-07-27 公開日 2006-04-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Atomic description of an enzyme reaction dominated by proton tunneling Science, 312, 2006
2AGY	Crystal structure of the Schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. Monoclinic form 分子名称: 2-(1H-INDOL-3-YL)ETHANIMINE, Aromatic amine dehydrogenase 著者 Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. 登録日 2005-07-27 公開日 2006-04-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Atomic description of an enzyme reaction dominated by proton tunneling Science, 312, 2006
6NRG	Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT57 分子名称: 2-{[3-fluoro-4-(1H-tetrazol-5-yl)phenyl]methyl}-3-hydroxy-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... 著者 Langelier, M.F, Pascal, J.M. 登録日 2019-01-23 公開日 2019-08-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
2AI8	E.coli Polypeptide Deformylase complexed with SB-485343 分子名称: NICKEL (II) ION, Peptide deformylase, [HYDROXY(3-PHENYLPROPYL)AMINO]METHANOL 著者 Smith, K.J, Petit, C.M, Aubart, K, Smyth, M, McManus, E, Jones, J, Fosberry, A, Lewis, C, Lonetto, M, Christensen, S.B. 登録日 2005-07-29 公開日 2005-09-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Variation and inhibitor binding in polypeptide deformylase from four different bacterial species. Protein Sci., 12, 2003
6NS0	Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis complexed with L-lysine and Cladosporin 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-01-24 公開日 2019-02-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and Cladosporin to be published
7BDN	Structure of the Streptomyces coelicolor small laccase - cubic crystal form 分子名称: COPPER (II) ION, Putative copper oxidase 著者 Zovo, K, Majumdar, S, Lukk, T. 登録日 2020-12-22 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Substitution of the Methionine Axial Ligand of the T1 Copper for the Fungal-like Phenylalanine Ligand (M298F) Causes Local Structural Perturbations that Lead to Thermal Instability and Reduced Catalytic Efficiency of the Small Laccase from Streptomyces coelicolor A3(2). Acs Omega, 7, 2022
6NFY	Crystal structure of nonphosphorylated, HPK1 kinase domain in complex with sunitinib in the inactive state. 分子名称: Mitogen-activated protein kinase kinase kinase kinase 1, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide 著者 Johnson, E, McTigue, M, Cronin, C.N. 登録日 2018-12-21 公開日 2019-05-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation. J.Biol.Chem., 294, 2019
6NRF	Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT103 分子名称: 2-({4-[4-(1H-benzimidazol-2-yl)piperazine-1-carbonyl]phenyl}methyl)-3-hydroxy-1-benzofuran-7-carboxamide, CHLORIDE ION, CITRIC ACID, ... 著者 Langelier, M.F, Pascal, J.M. 登録日 2019-01-23 公開日 2019-08-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
6ZGO	Thrombin in complex with D-Phe-Pro-2-chlorofuran derivative (13l) 分子名称: (2~{S})-1-[(2~{R})-2-azanyl-3-phenyl-propanoyl]-~{N}-[(5-chloranylfuran-2-yl)methyl]pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... 著者 Sandner, A, Heine, A, Klebe, G. 登録日 2020-06-19 公開日 2021-06-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Thrombin in complex with D-Phe-Pro-2-chlorofuran derivative (13l) To be published
6ZBY	Cryo-EM structure of the nitrilase from Pseudomonas fluorescens EBC191 at 3.3 Angstroms 分子名称: NitA 著者 Eppinger, E, Stolz, A, Sewell, B.T. 登録日 2020-06-09 公開日 2021-06-30 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM structure of the nitrilase from Pseudomonas fluorescens EBC191 at 3.3 Angstroms To Be Published
6ZHM	Crystal Structure of Staphylococcus aureus RsgA bound to GDP. 分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, Small ribosomal subunit biogenesis GTPase RsgA, ... 著者 Bennison, D.J, Rafferty, J.B, Corrigan, R.M. 登録日 2020-06-23 公開日 2021-06-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The Stringent Response Inhibits 70S Ribosome Formation in Staphylococcus aureus by Impeding GTPase-Ribosome Interactions. Mbio, 12, 2021
6NLL	1.80 A resolution structure of WT BfrB from Pseudomonas aeruginosa in complex with a protein-protein interaction inhibitor (analog 14) 分子名称: 4-{[3-(2,4-dihydroxyphenyl)propyl]amino}-1H-isoindole-1,3(2H)-dione, FE (II) ION, Ferroxidase, ... 著者 Lovell, S, Punchi-Hewage, A, Battaile, K.P, Yao, H, Nammalwar, B, Gnanasekaran, K.K, Bunce, R.A, Reitz, A.B, Rivera, M. 登録日 2019-01-08 公開日 2019-05-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity. J.Am.Chem.Soc., 141, 2019
6ZHL	Crystal Structure of Staphylococcus aureus RsgA bound to ppGpp. 分子名称: 1,2-ETHANEDIOL, GUANOSINE-5',3'-TETRAPHOSPHATE, Small ribosomal subunit biogenesis GTPase RsgA, ... 著者 Bennison, D.J, Rafferty, J.B, Corrigan, R.M. 登録日 2020-06-23 公開日 2021-06-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 The Stringent Response Inhibits 70S Ribosome Formation in Staphylococcus aureus by Impeding GTPase-Ribosome Interactions. Mbio, 12, 2021
6ZJO	Crystal Structure of Staphylococcus aureus RsgA. 分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, Small ribosomal subunit biogenesis GTPase RsgA, ... 著者 Bennison, D.J, Rafferty, J.B, Corrigan, R.M. 登録日 2020-06-29 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 The Stringent Response Inhibits 70S Ribosome Formation in Staphylococcus aureus by Impeding GTPase-Ribosome Interactions. Mbio, 12, 2021
6NWG	Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with fragment analogue 3a 分子名称: ATP-dependent dethiobiotin synthetase BioD, [(1R,2R)-2-(2-methoxybenzene-1-carbonyl)cyclopentyl]propanedioic acid 著者 Thompson, A.P, Polyak, S.W, Wegener, K.L, Bruning, J.B. 登録日 2019-02-06 公開日 2020-02-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.939 Å) 主引用文献 Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with fragment analogue 3a To Be Published
6NOW	Human Mitochondrial Alanyl-tRNA Synthetase C-Ala domain 分子名称: Alanine--tRNA ligase, mitochondrial 著者 Kuhle, B, Schimmel, P. 登録日 2019-01-16 公開日 2020-01-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.099 Å) 主引用文献 Relaxed sequence constraints favor mutational freedom in idiosyncratic metazoan mitochondrial tRNAs. Nat Commun, 11, 2020
2EID	Galactose Oxidase W290G mutant 分子名称: COPPER (II) ION, Galactose oxidase, SODIUM ION 著者 Phillips, S.E, McPherson, M.J, Knowles, P.F, Akyumani, N, Firbank, S.J, Tamber, S. 登録日 2007-03-12 公開日 2007-04-24 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Stacking Tryptophan of Galactose Oxidase: A Second-Coordination Sphere Residue that Has Profound Effects on Tyrosyl Radical Behavior and Enzyme Catalysis Biochemistry, 46, 2007

<996997998999100010011002100310041005100610071008100910101011>