3IJ7
 
 | | Directed 'in situ' Elongation as a Strategy to Characterize the Covalent Glycosyl-Enzyme Catalytic Intermediate of Human Pancreatic a-Amylase | | 分子名称: | 4-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranosyl fluoride, 4-O-methyl-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-2)-5-fluoro-alpha-L-idopyranose, CALCIUM ION, ... | | 著者 | Li, C, Zhang, R, Withers, S.G, Brayer, G.D. | | 登録日 | 2009-08-03 | | 公開日 | 2009-10-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Directed "in situ" inhibitor elongation as a strategy to structurally characterize the covalent glycosyl-enzyme intermediate of human pancreatic alpha-amylase
Biochemistry, 48, 2009
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4H8H
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1OT1
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1KGU
 | | THREE DIMENSIONAL STRUCTURE ANALYSIS OF THE R337A VARIANT OF HUMAN PANCREATIC ALPHA-AMYLASE | | 分子名称: | ALPHA-AMYLASE, PANCREATIC, CALCIUM ION | | 著者 | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | | 登録日 | 2001-11-28 | | 公開日 | 2002-01-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase.
Biochemistry, 41, 2002
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1P6W
 | | Crystal structure of barley alpha-amylase isozyme 1 (AMY1) in complex with the substrate analogue, methyl 4I,4II,4III-tri-thiomaltotetraoside (thio-DP4) | | 分子名称: | CALCIUM ION, PROTEIN (Alpha-amylase type A isozyme), alpha-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose, ... | | 著者 | Robert, X, Haser, R, Aghajari, N. | | 登録日 | 2003-04-30 | | 公開日 | 2003-10-14 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of barley alpha-amylase isozyme 1 reveals a novel role of domain C in substrate recognition and binding: a pair of sugar tongs
Structure, 11, 2003
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1RP9
 | | Crystal structure of barley alpha-amylase isozyme 1 (amy1) inactive mutant d180a in complex with acarbose | | 分子名称: | 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-amylase type 1 isozyme, ... | | 著者 | Robert, X, Haser, R, Aghajari, N. | | 登録日 | 2003-12-03 | | 公開日 | 2005-06-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Oligosaccharide Binding to Barley {alpha}-Amylase 1
J.Biol.Chem., 280, 2005
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1CPU
 | | SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, ... | | 著者 | Brayer, G.D, Sidhu, G, Maurus, R, Rydberg, E.H, Braun, C, Wang, Y, Nguyen, N.T, Overall, C.M, Withers, S.G. | | 登録日 | 1999-06-07 | | 公開日 | 1999-06-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques.
Biochemistry, 39, 2000
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4H8U
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1CLV
 | | YELLOW MEAL WORM ALPHA-AMYLASE IN COMPLEX WITH THE AMARANTH ALPHA-AMYLASE INHIBITOR | | 分子名称: | CALCIUM ION, CHLORIDE ION, PROTEIN (ALPHA-AMYLASE INHIBITOR), ... | | 著者 | Pereira, P.J.B, Lozanov, V, Patthy, A, Huber, R, Bode, W, Pongor, S, Strobl, S. | | 登録日 | 1999-05-04 | | 公開日 | 2000-05-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Specific inhibition of insect alpha-amylases: yellow meal worm alpha-amylase in complex with the amaranth alpha-amylase inhibitor at 2.0 A resolution.
Structure Fold.Des., 7, 1999
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1QI3
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1UH2
 | | Thermoactinomyces vulgaris R-47 alpha-amylase/malto-hexaose complex | | 分子名称: | CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | 著者 | Abe, A, Tonozuka, T, Sakano, Y, Kamitori, S. | | 登録日 | 2003-06-23 | | 公開日 | 2004-01-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Complex Structures of Thermoactinomyces vulgaris R-47 alpha-Amylase 1 with Malto-oligosaccharides Demonstrate the Role of Domain N Acting as a Starch-binding Domain
J.Mol.Biol., 335, 2004
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1QPK
 | | MUTANT (D193G) MALTOTETRAOSE-FORMING EXO-AMYLASE IN COMPLEX WITH MALTOTETRAOSE | | 分子名称: | CALCIUM ION, PROTEIN (MALTOTETRAOSE-FORMING AMYLASE), alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Yoshioka, Y, Hasegawa, K, Matsuura, Y, Katsube, Y, Kubota, M. | | 登録日 | 1999-05-26 | | 公開日 | 1999-11-17 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Roles of catalytic residues in alpha-amylases as evidenced by the structures of the product-complexed mutants of a maltotetraose-forming amylase.
Protein Eng., 12, 1999
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1BF2
 | | STRUCTURE OF PSEUDOMONAS ISOAMYLASE | | 分子名称: | CALCIUM ION, ISOAMYLASE | | 著者 | Katsuya, Y, Mezaki, Y, Kubota, M, Matsuura, Y. | | 登録日 | 1998-05-26 | | 公開日 | 1998-08-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structure of Pseudomonas isoamylase at 2.2 A resolution.
J.Mol.Biol., 281, 1998
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1UKQ
 | | Crystal structure of cyclodextrin glucanotransferase complexed with a pseudo-maltotetraose derived from acarbose | | 分子名称: | 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, CALCIUM ION, Cyclomaltodextrin glucanotransferase, ... | | 著者 | Haga, K, Kanai, R, Sakamoto, O, Harata, K, Yamane, K. | | 登録日 | 2003-09-01 | | 公開日 | 2004-02-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Effects of Essential Carbohydrate/Aromatic Stacking Interaction with Tyr100 and Phe259 on Substrate Binding of Cyclodextrin Glycosyltransferase from Alkalophilic Bacillus sp. 1011
J.Biochem.(Tokyo), 134, 2003
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4HOX
 | | The crystal structure of isomaltulose synthase from Erwinia rhapontici NX5 in complex with Tris | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ... | | 著者 | Xu, Z, Li, S, Xu, H, Zhou, J. | | 登録日 | 2012-10-23 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of isomaltulose synthase from Erwinia rhapontici NX5 in complex with Tris
to be published
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1RPK
 | | Crystal structure of barley alpha-amylase isozyme 1 (amy1) in complex with acarbose | | 分子名称: | 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-amylase type 1 isozyme, ... | | 著者 | Robert, X, Haser, R, Aghajari, N. | | 登録日 | 2003-12-03 | | 公開日 | 2005-06-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Oligosaccharide Binding to Barley {alpha}-Amylase 1
J.Biol.Chem., 280, 2005
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4HOZ
 | | The crystal structure of isomaltulose synthase mutant D241A from Erwinia rhapontici NX5 in complex with D-glucose | | 分子名称: | CALCIUM ION, GLYCEROL, Sucrose isomerase, ... | | 著者 | Xu, Z, Li, S, Xu, H, Zhou, J. | | 登録日 | 2012-10-23 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Structural Basis of Erwinia rhapontici Isomaltulose Synthase
Plos One, 8, 2013
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3CPU
 | | SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT | | 分子名称: | CALCIUM ION, CHLORIDE ION, Pancreatic alpha-amylase, ... | | 著者 | Brayer, G.D, Sidhu, G, Maurus, R, Rydberg, E.H, Braun, C, Wang, Y, Nguyen, N.T, Overall, C.M, Withers, S.G. | | 登録日 | 1999-06-08 | | 公開日 | 2001-06-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques.
Biochemistry, 39, 2000
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1KXT
 | | Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase | | 分子名称: | ALPHA-AMYLASE, PANCREATIC, CALCIUM ION, ... | | 著者 | Desmyter, A, Spinelli, S, Payan, F, Lauwereys, M, Wyns, L, Muyldermans, S, Cambillau, C. | | 登録日 | 2002-02-01 | | 公開日 | 2002-06-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.
J.Biol.Chem., 277, 2002
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1QI5
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3CZL
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4HP5
 | | The crystal structure of isomaltulose synthase mutant E295A from Erwinia rhapontici NX5 in complex with D-glucose | | 分子名称: | CALCIUM ION, GLYCEROL, Sucrose isomerase, ... | | 著者 | Xu, Z, Li, S, Xu, H, Zhou, J. | | 登録日 | 2012-10-23 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of isomaltulose synthase mutant E295A from Erwinia rhapontici NX5 in complex with D-glucose
to be published
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2AMG
 | | STRUCTURE OF HYDROLASE (GLYCOSIDASE) | | 分子名称: | 1,4-ALPHA-D-GLUCAN MALTOTETRAHYDROLASE, CALCIUM ION | | 著者 | Morishita, Y, Hasegawa, K, Matsuura, Y, Kubota, M, Sakai, S, Katsube, Y. | | 登録日 | 1996-12-23 | | 公開日 | 1997-04-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a maltotetraose-forming exo-amylase from Pseudomonas stutzeri.
J.Mol.Biol., 267, 1997
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1HVX
 | | BACILLUS STEAROTHERMOPHILUS ALPHA-AMYLASE | | 分子名称: | ALPHA-AMYLASE, CALCIUM ION, SODIUM ION | | 著者 | Suvd, D, Fujimoto, Z, Takase, K, Matsumura, M, Mizuno, H. | | 登録日 | 2001-01-08 | | 公開日 | 2001-01-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of Bacillus stearothermophilus alpha-amylase: possible factors determining the thermostability.
J.Biochem., 129, 2001
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1V3M
 | | Crystal structure of F283Y mutant cyclodextrin glycosyltransferase complexed with a pseudo-tetraose derived from acarbose | | 分子名称: | 4,6-dideoxy-alpha-D-xylo-hexopyranose-(1-4)-beta-D-galactopyranose, 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, CALCIUM ION, ... | | 著者 | Kanai, R, Haga, K, Akiba, T, Yamane, K, Harata, K. | | 登録日 | 2003-11-03 | | 公開日 | 2004-08-03 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Role of Phe283 in enzymatic reaction of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp.1011: Substrate binding and arrangement of the catalytic site
PROTEIN SCI., 13, 2004
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