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PDB: 127 件
4XFY
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BU of 4xfy by Molmil
Structure of the native full-length dehydrated HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, PENTAETHYLENE GLYCOL
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2014-12-29
公開日2015-06-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.
Science, 349, 2015
8CKV
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BU of 8ckv by Molmil
HIV-1 mature capsid hexamer from CA-IP6 CLPs
分子名称: Gag polyprotein
著者Stacey, J.C.V, Briggs, J.A.G.
登録日2023-02-16
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
7MN0
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BU of 7mn0 by Molmil
N74D mutant of the HIV-1 capsid protein
分子名称: IODIDE ION, capsid protein
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2021-04-30
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献TRIM5alpha Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection.
Viruses, 14, 2022
6OBH
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BU of 6obh by Molmil
Structure of HIV-1 CA 1/2-hexamer
分子名称: CA, SODIUM ION
著者Summers, B.J, Xiong, Y.
登録日2019-03-20
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms.
Cell Host Microbe, 26, 2019
8CKX
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BU of 8ckx by Molmil
HIV-1 mature capsid hexamer next to pentamer (type I) from CA-IP6 CLPs
分子名称: Gag polyprotein
著者Stacey, J.C.V, Briggs, J.A.G.
登録日2023-02-16
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
4U0D
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BU of 4u0d by Molmil
Hexameric HIV-1 CA in complex with Nup153 peptide, P212121 crystal form
分子名称: CHLORIDE ION, Gag polyprotein, Nuclear pore complex protein Nup153
著者Price, A.J, Jacques, D.A, James, L.C.
登録日2014-07-11
公開日2014-11-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Plos Pathog., 10, 2014
8CKZ
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BU of 8ckz by Molmil
HIV-1 mature capsid pentamer from CA-IP6 CLPs bound to Nup153 peptide
分子名称: Gag polyprotein
著者Stacey, J.C.V, Briggs, J.A.G.
登録日2023-02-16
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EET
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BU of 8eet by Molmil
T=1 particle HIV-1 CA M66A
分子名称: Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
著者Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T.
登録日2022-09-07
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
5HGL
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BU of 5hgl by Molmil
Hexameric HIV-1 CA, open conformation
分子名称: CHLORIDE ION, Capsid protein P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE
著者Price, A.J, Jacques, D.A, James, L.C.
登録日2016-01-08
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis.
Nature, 536, 2016
8G6O
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BU of 8g6o by Molmil
HIV-1 capsid lattice bound to IP6 and Lenacapavir
分子名称: Capsid protein
著者Highland, C.M, Dick, R.A.
登録日2023-02-15
公開日2023-05-03
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G6M
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BU of 8g6m by Molmil
HIV-1 CA lattice bound to IP6, pH 7.4
分子名称: Capsid protein
著者Highland, C.M, Dick, R.A.
登録日2023-02-15
公開日2023-05-03
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CL0
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BU of 8cl0 by Molmil
HIV-1 mature capsid hexamer next to pentamer (type I) from CA-IP6 CLPs bound to Nup153 peptide.
分子名称: Gag polyprotein, Nuclear pore complex protein Nup153
著者Stacey, J.C.V, Briggs, J.A.G.
登録日2023-02-16
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CKW
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BU of 8ckw by Molmil
HIV-1 mature capsid pentamer from CA-IP6 CLPs
分子名称: Gag polyprotein
著者Stacey, J.C.V, Briggs, J.A.G.
登録日2023-02-16
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CL3
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BU of 8cl3 by Molmil
HIV-1 mature capsid hexamer from CA-IP6 CLPs, bound to Sec24C peptide.
分子名称: Gag polyprotein, Protein transport protein Sec24C
著者Stacey, J.C.V, Briggs, J.A.G.
登録日2023-02-16
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CL4
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BU of 8cl4 by Molmil
HIV-1 mature capsid pentamer from CA-IP6 CLPs bound to Sec24C peptide
分子名称: Gag polyprotein
著者Stacey, J.C.V, Briggs, J.A.G.
登録日2023-02-16
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
7T13
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BU of 7t13 by Molmil
Hexameric HIV-1 (M-group) CA Q50Y mutant
分子名称: Capsid protein p24
著者Jacques, D.A, James, L.C.
登録日2021-12-01
公開日2022-10-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Evasion of cGAS and TRIM5 defines pandemic HIV.
Nat Microbiol, 7, 2022
7N9U
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BU of 7n9u by Molmil
CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
分子名称: Capsid protein, Nanobody
著者Gerber, E.E, Digianantonio, K.M, Tripler, T.N, Smaga, S.S, Summers, B.J, Xiong, Y.
登録日2021-06-18
公開日2022-06-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
To Be Published
6MQA
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BU of 6mqa by Molmil
Structure of HIV-1 CA P207S
分子名称: CHLORIDE ION, Capsid protein, IODIDE ION
著者Smaga, S.S, Xiong, Y.
登録日2018-10-09
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.199 Å)
主引用文献MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
6MQO
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BU of 6mqo by Molmil
Structure of HIV-1 CA G208R
分子名称: Capsid protein, IODIDE ION
著者Smaga, S.S, Xiong, Y.
登録日2018-10-10
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
6MQP
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BU of 6mqp by Molmil
Structure of HIV-1 CA T210K
分子名称: CHLORIDE ION, Capsid protein, IODIDE ION
著者Smaga, S.S, Xiong, Y.
登録日2018-10-10
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.296 Å)
主引用文献MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
8GDV
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BU of 8gdv by Molmil
Structure of M66I mutant of disulfide stabilized HIV-1 CA hexamer in complex with CPSF6 peptide and IP6
分子名称: Cleavage and polyadenylation specificity factor subunit 6, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
著者Briganti, L, Schope, L, Kvaratskhelia, M.
登録日2023-03-06
公開日2024-03-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of M66I mutant of disulfide stabilized HIV-1 CA hexamer in complex with CPSF6 peptide and IP6
To Be Published
8TY6
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BU of 8ty6 by Molmil
Disulfide-stabilized HIV-1 CA hexamer in complex with PQBP1 Nt
分子名称: Capsid protein p24
著者Piacentini, J, Pornillos, O, Ganser-Pornillos, B.K.
登録日2023-08-24
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular Determinants of PQBP1 Binding to the HIV-1 Capsid Lattice.
J.Mol.Biol., 436, 2024
8G6L
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BU of 8g6l by Molmil
HIV-1 capsid lattice bound to IP6, pH 6.2
分子名称: Capsid protein
著者Highland, C.M, Dick, R.A.
登録日2023-02-15
公開日2023-05-03
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
7E1I
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BU of 7e1i by Molmil
Crystal structure of Pr55Gag-matrix domain in complex with IP6 at ambient temperature in space group P1
分子名称: Capsid protein p24, INOSITOL HEXAKISPHOSPHATE
著者DeMirci, H, Destan, E.
登録日2021-02-01
公開日2021-08-04
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献Crystal structure of Pr55Gag-matrix domain in complex with IP6 at ambient temperature in space group P1
To Be Published
7RJ4
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BU of 7rj4 by Molmil
Co-crystal structure of lenacapavir bound to N74D mutant of disulfide stabilized HIV-1 CA hexamer
分子名称: CAPSID PROTEIN P24, CHLORIDE ION, IODIDE ION, ...
著者Bester, S.M, Kvaratskhelia, M.
登録日2021-07-20
公開日2022-07-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Structural and Mechanistic Bases of Viral Resistance to HIV-1 Capsid Inhibitor Lenacapavir.
Mbio, 13, 2022

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件を2024-07-10に公開中

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