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PDB: 11 件

2XR6
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BU of 2xr6 by Molmil
Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo trimannoside mimic.
分子名称: 2-AZIDOETHANOL, CALCIUM ION, CD209 ANTIGEN, ...
著者Thepaut, M, Suitkeviciute, I, Sattin, S, Reina, J, Bernardi, A, Fieschi, F.
登録日2010-09-10
公開日2011-10-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Unique Dc-Sign Clustering Activity of a Small Glycomimetic: A Lesson for Ligand Design.
Acs Chem.Biol., 9, 2014
2XR5
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BU of 2xr5 by Molmil
Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo dimannoside mimic.
分子名称: CALCIUM ION, CD209 ANTIGEN, CHLORIDE ION, ...
著者Thepaut, M, Suitkeviciute, I, Sattin, S, Reina, J, Bernardi, A, Fieschi, F.
登録日2010-09-10
公開日2011-10-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structure of a Glycomimetic Ligand in the Carbohydrate Recognition Domain of C-Type Lectin Dc-Sign. Structural Requirements for Selectivity and Ligand Design.
J.Am.Chem.Soc., 135, 2013
1SL4
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BU of 1sl4 by Molmil
Crystal Structure of DC-SIGN carbohydrate recognition domain complexed with Man4
分子名称: CALCIUM ION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, mDC-SIGN1B type I isoform
著者Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K.
登録日2004-03-05
公開日2004-06-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
1SL5
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BU of 1sl5 by Molmil
Crystal Structure of DC-SIGN carbohydrate recognition domain complexed with LNFP III (Dextra L504).
分子名称: CALCIUM ION, MAGNESIUM ION, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ...
著者Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K.
登録日2004-03-05
公開日2004-06-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
2IT6
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BU of 2it6 by Molmil
Crystal Structure of DCSIGN-CRD with man2
分子名称: CALCIUM ION, CD209 antigen, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Weis, W.I, Feinberg, H, Castelli, R, Drickamer, K, Seeberger, P.H.
登録日2006-10-19
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins.
J.Biol.Chem., 282, 2007
7NL7
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BU of 7nl7 by Molmil
Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand
分子名称: 3-Aminopropyl 2-deoxy-2-(4-phenyl-1,2,3-triazol-1-yl)-alpha-D-mannopyranoside, CALCIUM ION, DC-SIGN, ...
著者Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T.
登録日2021-02-22
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2.
J.Am.Chem.Soc., 143, 2021
6GHV
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BU of 6ghv by Molmil
Structure of a DC-SIGN CRD in complex with high affinity glycomimetic.
分子名称: CALCIUM ION, CD209 antigen, CHLORIDE ION, ...
著者Thepaut, M, Achilli, S, Medve, L, Bernardi, A, Fieschi, F.
登録日2018-05-09
公開日2019-09-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Enhancing Potency and Selectivity of a DC-SIGN Glycomimetic Ligand by Fragment-Based Design: Structural Basis.
Chemistry, 25, 2019
7NL6
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BU of 7nl6 by Molmil
Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand
分子名称: CALCIUM ION, DC-SIGN, CRD domain, ...
著者Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T.
登録日2021-02-22
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2.
J.Am.Chem.Soc., 143, 2021
2IT5
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BU of 2it5 by Molmil
Crystal Structure of DCSIGN-CRD with man6
分子名称: CALCIUM ION, CD209 antigen, DCSIGN-CRD, ...
著者Weis, W.I, Feinberg, H, Castelli, R, Drickamer, K, Seeberger, P.H.
登録日2006-10-19
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins.
J.Biol.Chem., 282, 2007
1K9I
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BU of 1k9i by Molmil
Complex of DC-SIGN and GlcNAc2Man3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, CALCIUM ION, mDC-SIGN1B type I isoform
著者Feinberg, H, Mitchell, D.A, Drickamer, K, Weis, W.I.
登録日2001-10-29
公開日2001-12-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR.
Science, 294, 2001
2B6B
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BU of 2b6b by Molmil
Cryo EM structure of Dengue complexed with CRD of DC-SIGN
分子名称: CD209 antigen, envelope glycoprotein
著者Pokidysheva, E, Zhang, Y, Battisti, A.J, Bator-Kelly, C.M, Chipman, P.R, Gregorio, G, Hendrickson, W.A, Kuhn, R.J, Rossmann, M.G.
登録日2005-09-30
公開日2006-03-07
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (25 Å)
主引用文献Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN
Cell(Cambridge,Mass.), 124, 2006

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