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PDB: 72 件
3MUY
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E. coli (lacZ) beta-galactosidase (R599A)
分子名称: Beta-D-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Dugdale, M.L, Vance, M, Driedger, M.L, Nibber, A, Tran, A, Huber, R.E.
登録日2010-05-03
公開日2011-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Importance of Arg-599 of beta-galactosidase (Escherichia coli) as an anchor for the open conformations of Phe-601 and the active-site loop
Biochem.Cell Biol., 88, 2010
3VDC
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E. coli (lacZ) beta-galactosidase (N460T) in complex with IPTG
分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
4V45
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E. COLI (lacZ) BETA-GALACTOSIDASE-TRAPPED 2-F-GALACTOSYL-ENZYME INTERMEDIATE
分子名称: 2-deoxy-2-fluoro-beta-D-galactopyranose, Beta-Galactosidase, MAGNESIUM ION, ...
著者Juers, D.H, McCarter, J.D, Withers, S.G, Matthews, B.W.
登録日2001-09-13
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Structural View of the Action of Escherichia Coli (Lacz) Beta-Galactosidase
Biochemistry, 40, 2001
8Q7Y
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ESIBD structure of beta-galactosidase
分子名称: Beta-galactosidase
著者Esser, T, Boehning, J, Bharat, T.A.M, Rauschenbach, S.
登録日2023-08-17
公開日2024-01-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Cryo-EM of soft-landed beta-galactosidase: Gas-phase and native structures are remarkably similar.
Sci Adv, 10, 2024
3T2P
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BU of 3t2p by Molmil
E. coli (lacZ) beta-galactosidase (S796D) in complex with IPTG
分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Jancewicz, L.J, Wheatley, R.W, Sutendra, G, Lee, M, Fraser, M, Huber, R.E.
登録日2011-07-22
公開日2012-01-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ser-796 of Beta-Galactosidase (E. coli) Plays a Key Role in Maintaining an Optimum Balance between the Opened and Closed Conformations of the Catalytically Important Active Site Loop
Arch.Biochem.Biophys., 517, 2012
7BRS
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BU of 7brs by Molmil
E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSA02
分子名称: 8-[2-[(E)-2-[4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethenyl]-3,3-dimethyl-indol-1-ium-1-yl]octanoic acid, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Chen, X, Hu, Y.L, Gao, Y, Yuan, R, Guo, Y.
登録日2020-03-30
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Two-Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence.
Angew.Chem.Int.Ed.Engl., 60, 2021
4V44
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BU of 4v44 by Molmil
E. COLI (lacZ) BETA-GALACTOSIDASE IN COMPLEX WITH 2-F-LACTOSE
分子名称: 2-deoxy-2-fluoro-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Beta-Galactosidase, MAGNESIUM ION, ...
著者Juers, D.H, McCarter, J.D, Withers, S.G, Matthews, B.W.
登録日2001-09-13
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A Structural View of the Action of Escherichia Coli (Lacz) Beta-Galactosidase
Biochemistry, 40, 2001
3VD5
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E. coli (lacZ) beta-galactosidase (N460S)
分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3IAQ
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E. coli (lacz) beta-galactosidase (E416V)
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Lo, S, Dugdale, M.L, Jeerh, N, Ku, T, Roth, N.J, Huber, R.E.
登録日2009-07-14
公開日2009-12-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Studies of Glu-416 variants of beta-galactosidase (E. coli) show that the active site Mg(2+) is not important for structure and indicate that the main role of Mg (2+) is to mediate optimization of active site chemistry
Protein J., 29, 2010
7BTK
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BU of 7btk by Molmil
E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSA01
分子名称: 4-[[2-[(E)-2-[4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethenyl]-3,3-dimethyl-2H-indol-1-yl]methyl]benzoic acid, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Chen, X, Hu, Y.L, Liu, Q.M, Gao, Y, Yuan, R, Guo, Y.
登録日2020-04-01
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Two-Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence.
Angew.Chem.Int.Ed.Engl., 60, 2021
3VD3
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BU of 3vd3 by Molmil
E. coli (lacZ) beta-galactosidase (N460D)
分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
1F4H
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BU of 1f4h by Molmil
E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC)
分子名称: BETA-GALACTOSIDASE, MAGNESIUM ION
著者Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W.
登録日2000-06-07
公開日2001-02-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.
Protein Sci., 9, 2000
1F4A
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BU of 1f4a by Molmil
E. COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC)
分子名称: BETA-GALACTOSIDASE, MAGNESIUM ION
著者Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W.
登録日2000-06-07
公開日2001-02-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.
Protein Sci., 9, 2000
6KUZ
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BU of 6kuz by Molmil
E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSL01
分子名称: 3-(1,3-benzothiazol-2-yl)-2-[[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]methoxy]-5-methyl-benzaldehyde, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Chen, X, Hu, Y.L, Li, X.K, Guo, Y, Li, J.
登録日2019-09-03
公開日2020-07-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated beta-galactosidase.
Chem Sci, 11, 2020
3VD7
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BU of 3vd7 by Molmil
E. coli (lacZ) beta-galactosidase (N460S) in complex with galactotetrazole
分子名称: (5R, 6S, 7S, ...
著者Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
登録日2012-01-04
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
8BK8
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Cryo-EM structure of beta-galactosidase at 2.9 A resolution plunged 205 ms after mixing with apoferritin
分子名称: Beta-galactosidase
著者Torino, S, Dhurandhar, M, Efremov, R.
登録日2022-11-08
公開日2023-08-09
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
1HN1
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BU of 1hn1 by Molmil
E. COLI (LAC Z) BETA-GALACTOSIDASE (ORTHORHOMBIC)
分子名称: BETA-GALACTOSIDASE, MAGNESIUM ION, SODIUM ION
著者Juers, D.H, Matthews, B.W.
登録日2000-12-05
公開日2001-12-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Reversible lattice repacking illustrates the temperature dependence of macromolecular interactions.
J.Mol.Biol., 311, 2001
3E1F
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BU of 3e1f by Molmil
E.Coli (lacZ) beta-galactosidase (H418E) in complex with galactose
分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Huber, R.E, Dugdale, M.L.
登録日2008-08-04
公開日2009-06-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli).
Protein Sci., 18, 2009
8BKG
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BU of 8bkg by Molmil
Cryo-EM structure of beta-galactosidase at 3.2 A resolution plunged 35 ms after mixing with apoferritin
分子名称: Beta-galactosidase
著者Torino, S, Dhurandhar, M, Efremov, R.
登録日2022-11-09
公開日2023-08-09
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
3J7H
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Structure of beta-galactosidase at 3.2-A resolution obtained by cryo-electron microscopy
分子名称: Beta-galactosidase, MAGNESIUM ION
著者Bartesaghi, A, Matthies, D, Banerjee, S, Merk, A, Subramaniam, S.
登録日2014-06-30
公開日2014-07-30
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of beta-galactosidase at 3.2- angstrom resolution obtained by cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 111, 2014
8BK7
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BU of 8bk7 by Molmil
Cryo-EM structure of beta-galactosidase at 3.3 A resolution plunged 5 ms after mixing with apoferritin
分子名称: Beta-galactosidase
著者Torino, S, Dhurandhar, M, Efremov, R.
登録日2022-11-08
公開日2023-08-09
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
4CKD
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BU of 4ckd by Molmil
Model of complex between the E.coli enzyme beta-galactosidase and four single chain Fv antibody domains scFv13R4.
分子名称: BETA-GALACTOSIDASE, SCFV13R4 ANTIBODY FV HEAVY CHAIN, SCFV13R4 ANTIBODY FV LIGHT CHAIN
著者Vinothkumar, K.R, McMullan, G, Henderson, R.
登録日2014-01-03
公開日2014-01-15
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Molecular Mechanism of Antibody-Mediated Activation of Beta-Galactosidase.
Structure, 22, 2014
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