2X0H
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![BU of 2x0h by Molmil](/molmil-images/mine/2x0h) | BtGH84 Michaelis complex | 分子名称: | 3,4-difluorophenyl 2-deoxy-2-[(difluoroacetyl)amino]-beta-D-glucopyranoside, CALCIUM ION, GLYCEROL, ... | 著者 | He, Y, Davies, G.J. | 登録日 | 2009-12-08 | 公開日 | 2010-01-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Visualizing the Reaction Coordinate of an O-Glcnac Hydrolase J.Am.Chem.Soc., 132, 2010
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2VVS
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![BU of 2vvs by Molmil](/molmil-images/mine/2vvs) | BtGH84 structure in complex with PUGNAc | 分子名称: | O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, O-GLCNACASE BT_4395 | 著者 | Macauley, M.S, Bubb, A, Martinez-Fleites, C, Davies, G.J, Vocadlo, D.J. | 登録日 | 2008-06-11 | 公開日 | 2008-09-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Elevation of Global O-Glcnac Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-Glcnacase Does not Induce Insulin Resistance J.Biol.Chem., 283, 2008
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2J4G
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![BU of 2j4g by Molmil](/molmil-images/mine/2j4g) | Bacteroides thetaiotaomicron GH84 O-GlcNAcase in complex with n-butyl- thiazoline inhibitor | 分子名称: | (3AR,5R,6S,7R,7AR)-5-(HYDROXYMETHYL)-2-PROPYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL, ACETATE ION, GLYCEROL, ... | 著者 | Dennis, R.J, Davies, G.J. | 登録日 | 2006-08-31 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Analysis of Pugnac and Nag-Thiazoline as Transition State Analogues for Human O-Glcnacase: Mechanistic and Structural Insights Into Inhibitor Selectivity and Transition State Poise. J.Am.Chem.Soc., 129, 2007
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2W67
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![BU of 2w67 by Molmil](/molmil-images/mine/2w67) | BtGH84 in complex with FMA34 | 分子名称: | CALCIUM ION, GLYCEROL, N-[(3S,4R,5R,6R)-4,5,6-trihydroxyazepan-3-yl]acetamide, ... | 著者 | He, Y, Davies, G.J. | 登録日 | 2008-12-17 | 公開日 | 2009-04-14 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Molecular Basis for Inhibition of Gh84 Glycoside Hydrolases by Substituted Azepanes: Conformational Flexibility Enables Probing of Substrate Distortion. J.Am.Chem.Soc., 131, 2009
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4AIU
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![BU of 4aiu by Molmil](/molmil-images/mine/4aiu) | A complex structure of BtGH84 | 分子名称: | (3AR,5R,6S,7R,7AR)-2,5-BIS(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]OXAZOLE-6,7-DIOL, CALCIUM ION, O-GLCNACASE BT_4395 | 著者 | He, Y, Davies, G.J. | 登録日 | 2012-02-13 | 公開日 | 2012-06-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: Intracellular Beta-O-Linked N-Glycolylglucosamine (Glcngc), Udp-Glcngc, and the Biochemical and Structural Rationale for the Substrate Tolerance of Beta-O-Linked Beta-N-Acetylglucosaminidase. J.Biol.Chem., 287, 2012
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2W66
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![BU of 2w66 by Molmil](/molmil-images/mine/2w66) | BtGH84 in complex with HQ602 | 分子名称: | CALCIUM ION, GLYCEROL, N-[(3R,4S,5R,6R,7R)-3,5,6-trihydroxy-7-(hydroxymethyl)azepan-4-yl]acetamide, ... | 著者 | He, Y, Davies, G.J. | 登録日 | 2008-12-17 | 公開日 | 2009-04-14 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Molecular Basis for Inhibition of Gh84 Glycoside Hydrolases by Substituted Azepanes: Conformational Flexibility Enables Probing of Substrate Distortion. J.Am.Chem.Soc., 131, 2009
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2WCA
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![BU of 2wca by Molmil](/molmil-images/mine/2wca) | BtGH84 in complex with n-butyl pugnac | 分子名称: | CALCIUM ION, O-GLCNACASE BT_4395, [[(3R,4R,5S,6R)-3-(BUTANOYLAMINO)-4,5-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YLIDENE]AMINO] N-PHENYLCARBAMATE | 著者 | He, Y, Davies, G.J. | 登録日 | 2009-03-10 | 公開日 | 2009-06-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Insight Into a Strategy for Attenuating Ampc- Mediated Beta-Lactam Resistance: Structural Basis for Selective Inhibition of the Glycoside Hydrolase Nagz. Protein Sci., 18, 2009
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2W4X
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![BU of 2w4x by Molmil](/molmil-images/mine/2w4x) | BtGH84 in complex with STZ | 分子名称: | CALCIUM ION, GLYCEROL, O-GLCNACASE BT_4395, ... | 著者 | He, Y, Bubb, A, Martinez-Fleites, C, Davies, G.J. | 登録日 | 2008-12-02 | 公開日 | 2009-02-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structural Insight Into the Mechanism of Streptozotocin Inhibition of O-Glcnacase. Carbohydr.Res., 344, 2009
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