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PDB: 128 件

6OVC
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BU of 6ovc by Molmil
hMcl1 inhibitor complex
分子名称: (2S)-N-(benzylsulfonyl)-4-(cyclobutylmethyl)-2-(2,4-dichlorophenyl)-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Poppe, L.
登録日2019-05-07
公開日2019-05-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies.
Cancer Discov, 8, 2018
2MHS
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NMR Structure of human Mcl-1
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1
著者Liu, G, Poppe, L, Aoki, K, Yamane, H, Lewis, J, Szyperski, T.
登録日2013-12-04
公開日2014-05-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献High-Quality NMR Structure of Human Anti-Apoptotic Protein Domain Mcl-1(171-327) for Cancer Drug Design.
Plos One, 9, 2014
2KBW
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Solution Structure of human Mcl-1 complexed with human Bid_BH3 peptide
分子名称: BH3-interacting domain death agonist, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Liu, Q, Moldoveanu, T, Sprules, T, Matta-Camacho, E, Mansur-Azzam, N, Gehring, K.
登録日2008-12-09
公開日2009-12-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Apoptotic regulation by MCL-1 through heterodimerization.
J.Biol.Chem., 285, 2010

221371

件を2024-06-19に公開中

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