7MN5
| Structure of the HER2/HER3/NRG1b Heterodimer Extracellular Domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... | 著者 | Diwanji, D, Trenker, R, Verba, K.A, Jura, N. | 登録日 | 2021-04-30 | 公開日 | 2021-10-27 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structures of the HER2-HER3-NRG1 beta complex reveal a dynamic dimer interface. Nature, 600, 2021
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3U7U
| Crystal structure of extracellular region of human epidermal growth factor receptor 4 in complex with neuregulin-1 beta | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuregulin 1, Receptor tyrosine-protein kinase erbB-4 | 著者 | Liu, P, Cleveland IV, T.E, Bouyain, S, Longo, P.A, Leahy, D.J. | 登録日 | 2011-10-14 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | A single ligand is sufficient to activate EGFR dimers. Proc.Natl.Acad.Sci.USA, 109, 2012
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7MN6
| Structure of the HER2 S310F/HER3/NRG1b Heterodimer Extracellular Domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... | 著者 | Diwanji, D, Trenker, R, Verba, K.A, Jura, N. | 登録日 | 2021-04-30 | 公開日 | 2021-10-27 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Structures of the HER2-HER3-NRG1 beta complex reveal a dynamic dimer interface. Nature, 600, 2021
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8U4L
| Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... | 著者 | Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N. | 登録日 | 2023-09-10 | 公開日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain To Be Published
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8U4I
| Structure of the HER4/NRG1b Homodimer Extracellular Domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... | 著者 | Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N. | 登録日 | 2023-09-10 | 公開日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain To Be Published
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7MN8
| Structure of the HER2/HER3/NRG1b Heterodimer Extracellular Domain bound to Trastuzumab Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... | 著者 | Diwanji, D, Trenker, R, Verba, K.A, Jura, N. | 登録日 | 2021-04-30 | 公開日 | 2021-11-10 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Structures of the HER2-HER3-NRG1 beta complex reveal a dynamic dimer interface. Nature, 600, 2021
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1HRF
| SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4 | 分子名称: | HEREGULIN ALPHA | 著者 | Nagata, K, Kohda, D, Hatanaka, H, Ichikawa, S, Inagaki, F. | 登録日 | 1994-07-21 | 公開日 | 1994-10-15 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4. EMBO J., 13, 1994
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7SJL
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1HRE
| SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4 | 分子名称: | HEREGULIN ALPHA | 著者 | Nagata, K, Kohda, D, Hatanaka, H, Ichikawa, S, Inagaki, F. | 登録日 | 1994-07-21 | 公開日 | 1994-10-15 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4. EMBO J., 13, 1994
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1HAF
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1HAE
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