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PDB: 16 件
6XP5
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Head-Middle module of Mediator
分子名称: HEAT, Med22, Mediator of RNA polymerase II transcription subunit 1, ...
著者Zhang, H.Q, Chen, D.C, Kornberg, R.D.
登録日2020-07-08
公開日2021-03-03
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Mediator structure and conformation change.
Mol.Cell, 81, 2021
8CEO
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BU of 8ceo by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Wang, H, Cramer, P.
登録日2023-02-02
公開日2023-03-08
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8GXS
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PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X.
登録日2022-09-21
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
8GXQ
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PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y.
登録日2022-09-21
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (5.04 Å)
主引用文献Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
8T1I
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BU of 8t1i by Molmil
Atomic model of the mammalian Mediator complex with MED26 subunit
分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
著者Zhao, H, Asturias, F.
登録日2023-06-02
公開日2024-06-12
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.68 Å)
主引用文献An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II.
Mol.Cell, 2024
8T1L
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BU of 8t1l by Molmil
Atomic model of the mammalian mouse Mediator complex with CKM module
分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
著者Zhao, H, Asturias, F.
登録日2023-06-02
公開日2024-07-03
実験手法ELECTRON MICROSCOPY (4.83 Å)
主引用文献A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers.
To Be Published
8T9D
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BU of 8t9d by Molmil
CryoEM structure of TR-TRAP
分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
著者Zhao, H, Asturias, F.
登録日2023-06-23
公開日2024-07-03
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.66 Å)
主引用文献An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II.
Mol.Cell, 2024
7ENJ
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BU of 7enj by Molmil
Human Mediator (deletion of MED1-IDR) in a Tail-bent conformation (MED-B)
分子名称: Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ...
著者Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y.
登録日2021-04-17
公開日2021-05-19
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7ENA
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TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
登録日2021-04-16
公開日2021-05-26
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7ENC
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TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
登録日2021-04-16
公開日2021-05-26
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (4.13 Å)
主引用文献Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7EMF
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BU of 7emf by Molmil
Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation
分子名称: Isoform 2 of Mediator of RNA polymerase II transcription subunit 16, Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, ...
著者Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y.
登録日2021-04-13
公開日2021-05-05
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7UIL
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BU of 7uil by Molmil
Mediator-PIC Early (Tail A/B Dimer)
分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 15, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIF
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BU of 7uif by Molmil
Mediator-PIC Early (Core B)
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-02-15
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIG
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BU of 7uig by Molmil
Mediator-PIC Early (Mediator A)
分子名称: DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIO
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BU of 7uio by Molmil
Mediator-PIC Early (Composite Model)
分子名称: ALANINE, ASPARTIC ACID, DNA (37-MER), ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-03-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UI9
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BU of 7ui9 by Molmil
Core Mediator-PICearly (Copy A)
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-28
公開日2023-02-15
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023

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件を2024-07-24に公開中

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