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PDB: 38 件

1JY2
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Crystal Structure of the Central Region of Bovine Fibrinogen (E5 fragment) at 1.4 Angstroms Resolution
分子名称: FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA-B CHAIN
著者Madrazo, J, Brown, J.H, Litvinovich, S, Dominguez, R, Yakovlev, S, Medved, L, Cohen, C.
登録日2001-09-10
公開日2001-10-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of the central region of bovine fibrinogen (E5 fragment) at 1.4-A resolution.
Proc.Natl.Acad.Sci.USA, 98, 2001
1JY3
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Crystal Structure of the Central Region of Bovine Fibrinogen (E5 Fragment) at 1.4 Angstroms Resolution
分子名称: FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA-B CHAIN
著者Madrazo, J, Brown, J.H, Litvinovich, S, Dominguez, R, Yakovlev, S, Medved, L, Cohen, C.
登録日2001-09-10
公開日2001-10-17
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the central region of bovine fibrinogen (E5 fragment) at 1.4-A resolution.
Proc.Natl.Acad.Sci.USA, 98, 2001
3BVH
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Crystal Structure of Recombinant gammaD364A Fibrinogen Fragment D with the Peptide Ligand Gly-Pro-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 4-mer peptide GPRP, CALCIUM ION, ...
著者Bowley, S.R, Merenbloom, B.K, Betts, L, Okumura, N, Heroux, A, Gorkun, O.V, Lord, S.T.
登録日2008-01-07
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Polymerization-defective fibrinogen variant gammaD364A binds knob "A" peptide mimic.
Biochemistry, 47, 2008
2A45
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Crystal structure of the complex between thrombin and the central "E" region of fibrin
分子名称: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Fibrinogen alpha chain, Fibrinogen beta chain, ...
著者Pechik, I, Madrazo, J, Gilliland, G.L, Medved, L.
登録日2005-06-27
公開日2006-05-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly.
Biochemistry, 45, 2006
2XNX
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BC1 fragment of streptococcal M1 protein in complex with human fibrinogen
分子名称: FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA CHAIN, ...
著者Macheboeuf, P, Y Fu, C, Zinkernagel, A.S, Johnson, J.E, Nizet, V, Ghosh, P.
登録日2010-08-06
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
Nature, 472, 2011
2FFD
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Fibrinogen Fragment D with "A" knob peptide mimic GPRVVE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E Chain, ...
著者Betts, L.
登録日2005-12-19
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献The structure of fibrinogen fragment D with the 'A' knob peptide GPRVVE.
THROMB.HAEMOST., 4, 2006
3H32
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Crystal structure of D-dimer from human fibrin complexed with Gly-His-Arg-Pro-Tyr-amide
分子名称: CALCIUM ION, Fibrin B knob pentapeptide, Fibrinogen alpha chain, ...
著者Doolittle, R.F, Pandi, L.
登録日2009-04-15
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Two families of synthetic peptides that enhance fibrin turbidity and delay fibrinolysis by different mechanisms.
Biochemistry, 48, 2009
2XNY
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A fragment of streptococcal M1 protein in complex with human fibrinogen
分子名称: FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA CHAIN, ...
著者Macheboeuf, P, Y Fu, C, Zinkernagel, A.S, Johnson, J.E, Nizet, V, Ghosh, P.
登録日2010-08-06
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (7.5 Å)
主引用文献Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
Nature, 472, 2011
2Z4E
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Crystal Structure of D-Dimer from Human Fibrin Complexed with Gly-His-Arg-Pro-Tyr-amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Doolittle, R.F, Pandi, L.
登録日2007-06-16
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
Biochemistry, 46, 2007
3E1I
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Crystal Structure of BbetaD432A Variant Fibrinogen Fragment D with the Peptide Ligand Gly-His-Arg-Pro-amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
著者Bowley, S.R, Lord, S.T.
登録日2008-08-04
公開日2009-01-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Fibrinogen variant BbetaD432A has normal polymerization but does not bind knob "B".
Blood, 113, 2009
3HUS
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Crystal structure of recombinant gamma N308K fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
著者Lord, S.T, Bowley, S.R, Okumura, N.
登録日2009-06-15
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Impaired protofibril formation in fibrinogen gammaN308K is due to altered D:D and "A:a" interactions.
Biochemistry, 48, 2009
3GHG
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Crystal Structure of Human Fibrinogen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A knob, B knob, ...
著者Doolittle, R.F, Kollman, J.M, Sawaya, M.R, Pandi, L, Riley, M.
登録日2009-03-03
公開日2009-05-19
最終更新日2023-05-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of human fibrinogen.
Biochemistry, 48, 2009
1DEQ
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THE CRYSTAL STRUCTURE OF MODIFIED BOVINE FIBRINOGEN (AT ~4 ANGSTROM RESOLUTION)
分子名称: FIBRINOGEN, FIBRINOGEN (ALPHA CHAIN), FIBRINOGEN (BETA CHAIN), ...
著者Brown, J.H, Volkmann, N, Jun, G, Henschen-Edman, A.H, Cohen, C.
登録日1999-11-15
公開日2000-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The crystal structure of modified bovine fibrinogen.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EI3
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CRYSTAL STRUCTURE OF NATIVE CHICKEN FIBRINOGEN
分子名称: FIBRINOGEN
著者Yang, Z, Mochalkin, I, Veerapandian, L, Riley, M, Doolittle, R.F.
登録日2000-02-23
公開日2000-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Crystal structure of native chicken fibrinogen at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 97, 2000
1RF1
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Crystal Structure of Fragment D of gammaE132A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
登録日2003-11-07
公開日2004-03-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Calcium-Binding Site beta2, Adjacent to the "b" Polymerization Site, Modulates Lateral Aggregation of Protofibrils during Fibrin Polymerization.
Biochemistry, 43, 2004
1RE4
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Crystal Structure of Fragment D of BbetaD398A Fibrinogen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
登録日2003-11-06
公開日2004-05-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
Biochemistry, 43, 2004
2OYI
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Crystal Structure of Fragment D of gammaD298,301A Fibrinogen with the Peptide Ligand Gly-Pro-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
著者Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
登録日2007-02-22
公開日2007-05-15
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Probing the gamma2 Calcium-Binding Site: Studies with gammaD298,301A Fibrinogen Reveal Changes in the gamma294-301 Loop that Alter the Integrity of the "a" Polymerization Site.
Biochemistry, 46, 2007
1RF0
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Crystal Structure of Fragment D of gammaE132A Fibrinogen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
登録日2003-11-07
公開日2004-03-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Calcium-Binding Site beta2, Adjacent to the "b" Polymerization Site, Modulates Lateral Aggregation of Protofibrils during Fibrin Polymerization.
Biochemistry, 43, 2004
2OYH
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Crystal Structure of Fragment D of gammaD298,301A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
著者Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
登録日2007-02-22
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Probing the gamma2 Calcium-Binding Site: Studies with gammaD298,301A Fibrinogen Reveal Changes in the gamma294-301 Loop that Alter the Integrity of the "a" Polymerization Site.
Biochemistry, 46, 2007
2Q9I
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Crystal Structure of D-Dimer from Human Fibrin Complexed with Met-His-Arg-Pro-Tyr-amide.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrin B Knob (GHRPam), ...
著者Doolittle, R.F, Pandi, L.
登録日2007-06-12
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
Biochemistry, 46, 2007
1N86
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Crystal structure of human D-dimer from cross-linked fibrin complexed with GPR and GHRPLDK peptide ligands.
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, Fibrin alpha/alpha-E chain, ...
著者Yang, Z, Pandi, L, Doolittle, R.F.
登録日2002-11-19
公開日2003-01-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
Biochemistry, 41, 2002
1N8E
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Fragment Double-D from Human Fibrin
分子名称: Fibrin alpha/alpha-E chain, Fibrin beta chain, Fibrin gamma chain
著者Yang, Z, Pandi, L, Doolittle, R.F.
登録日2002-11-20
公開日2003-01-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献The Crystal Structure of Fragment Double-D from Cross-Linked Lamprey Fibrin Reveals Isopeptide Linkages across an Unexpected D-D Interface
Biochemistry, 41, 2002
1N73
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Fibrin D-Dimer, Lamprey complexed with the PEPTIDE LIGAND: GLY-HIS-ARG-PRO-AMIDE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrin alpha-1 chain, ...
著者Yang, Z, Pandi, L, Doolittle, R.F.
登録日2002-11-12
公開日2003-01-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface
Biochemistry, 41, 2002
2HLO
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Crystal Structure of Fragment D-dimer from Human Fibrin Complexed with Gly-hydroxyPro-Arg-Pro-amide
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Doolittle, R.F, Kollman, J.M, Chen, A, Pandi, L.
登録日2006-07-08
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献

2HPC
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Crystal structure of fragment D from Human Fibrinogen Complexed with Gly-Pro-Arg-Pro-amide.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
著者Doolittle, R.F, Kollman, J.M, Chen, A, Pandi, L.
登録日2006-07-17
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献

 

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