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PDB: 1358 件

2CXC
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Crystal structure of archaeal transcription termination factor NusA
分子名称: NusA
著者Shibata, R, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-06-28
公開日2005-12-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure and RNA-binding analysis of the archaeal transcription factor NusA
Biochem.Biophys.Res.Commun., 355, 2007
2CY1
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Crystal structure of APE1850
分子名称: NusA protein homolog
著者Shibata, R, Bessho, Y, Umehara, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-04
公開日2006-01-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallization of the archaeal transcription termination factor NusA: a significant decrease in twinning under microgravity conditions
Acta Crystallogr.,Sect.F, 63, 2007
1WH9
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Solution structure of the KH domain of human ribosomal protein S3
分子名称: 40S ribosomal protein S3
著者Nameki, N, Tomizawa, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the KH domain of human ribosomal protein S3
To be Published
5UQ7
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70S ribosome complex with dnaX mRNA stemloop and E-site tRNA ("in" conformation)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, Y, Hong, S, Skiniotis, G, Dunham, C.M.
登録日2017-02-07
公開日2018-03-07
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Alternative Mode of E-Site tRNA Binding in the Presence of a Downstream mRNA Stem Loop at the Entrance Channel.
Structure, 26, 2018
1EGA
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CRYSTAL STRUCTURE OF A WIDELY CONSERVED GTPASE ERA
分子名称: PROTEIN (GTP-BINDING PROTEIN ERA), SULFATE ION
著者Chen, X, Ji, X.
登録日1998-12-01
公開日1999-07-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of ERA: a GTPase-dependent cell cycle regulator containing an RNA binding motif.
Proc.Natl.Acad.Sci.USA, 96, 1999
6P5N
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Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1
分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
著者Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
登録日2019-05-30
公開日2019-09-25
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
7NWT
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Initiated 70S ribosome in complex with 2A protein from encephalomyocarditis virus (EMCV)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Hill, C.H, Napthine, S, Pekarek, L, Kibe, A, Firth, A.E, Graham, S.C, Caliskan, N, Brierley, I.
登録日2021-03-17
公開日2021-12-15
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Structural and molecular basis for Cardiovirus 2A protein as a viral gene expression switch
Nat Commun, 12, 2021
7O5B
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Cryo-EM structure of a Bacillus subtilis MifM-stalled ribosome-nascent chain complex with (p)ppGpp-SRP bound
分子名称: 16S rRNA (1533-MER), 23S rRNA (2887-MER), 30S ribosomal protein S10, ...
著者Kratzat, H, Czech, L, Berninghausen, O, Bange, G, Beckmann, R.
登録日2021-04-08
公開日2022-02-02
最終更新日2022-03-09
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp.
Nat Commun, 13, 2022
6P5K
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Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 3)
分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
著者Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
登録日2019-05-30
公開日2019-09-18
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
2VQF
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Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U-G wobble pairing during decoding
分子名称: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Kurata, S, Weixlbaumer, A, Ohtsuki, T, Shimazaki, T, Wada, T, Kirino, Y, Takai, K, Watanabe, K, Ramakrishnan, V, Suzuki, T.
登録日2008-03-14
公開日2008-04-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Modified Uridines with C5-Methylene Substituents at the First Position of the tRNA Anticodon Stabilize U.G Wobble Pairing During Decoding.
J.Biol.Chem., 283, 2008
3T1H
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Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA lysine 3 (tRNALys3) bound to an mRNA with an AAA-codon in the A-site and Paromomycin
分子名称: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F.
登録日2011-07-21
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
J.Mol.Biol., 416, 2012
2VQE
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Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U-G wobble pairing during decoding
分子名称: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Kurata, S, Weixlbaumer, A, Ohtsuki, T, Shimazaki, T, Wada, T, Kirino, Y, Takai, K, Watanabe, K, Ramakrishnan, V, Suzuki, T.
登録日2008-03-13
公開日2008-04-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Modified Uridines with C5-Methylene Substituents at the First Position of the tRNA Anticodon Stabilize U.G Wobble Pairing During Decoding.
J.Biol.Chem., 283, 2008
3T1Y
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Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F.
登録日2011-07-22
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
J.Mol.Biol., 416, 2012
2BA0
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Archaeal exosome core
分子名称: Archaeal exosome RNA binding protein RRP4, Archaeal exosome RNA binding protein RRP41, Archaeal exosome RNA binding protein RRP42
著者Buttner, K, Wenig, K, Hopfner, K.P.
登録日2005-10-13
公開日2005-11-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural framework for the mechanism of archaeal exosomes in RNA processing.
Mol.Cell, 20, 2005
2F4V
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30S ribosome + designer antibiotic
分子名称: (2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE, (2S,4S,4AR,5AS,6S,11R,11AS,12R,12AR)-7-CHLORO-4-(DIMETHYLAMINO)-6,10,11,12-TETRAHYDROXY-1,3-DIOXO-1,2,3,4,4A,5,5A,6,11,11A,12,12A-DODECAHYDROTETRACENE-2-CARBOXAMIDE, 16S ribosomal RNA, ...
著者Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S.
登録日2005-11-24
公開日2006-07-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Interactions of designer antibiotics and the bacterial ribosome aminoacyl-tRNA site
Chem.Biol., 13, 2006
2XR1
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DIMERIC ARCHAEAL CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR WITH N-TERMINAL KH DOMAINS (KH-CPSF) FROM METHANOSARCINA MAZEI
分子名称: CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 100 KD SUBUNIT, ZINC ION
著者Mir-Montazeri, B, Ammelburg, M, Forouzan, D, Lupas, A.N, Hartmann, M.D.
登録日2010-09-08
公開日2010-10-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal Structure of a Dimeric Archaeal Cleavage and Polyadenylation Specificity Factor.
J.Struct.Biol., 173, 2011
3OTO
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Crystal Structure of the 30S ribosomal subunit from a KsgA mutant of Thermus thermophilus (HB8)
分子名称: 16S rRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Demirci, H, Murphy IV, F, Belardinelli, R, Kelley, A.C, Ramakrishnan, V, Gregory, S.T, Dahlberg, A.E, Jogl, G.
登録日2010-09-13
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.69 Å)
主引用文献Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function.
Rna, 16, 2010
3R9X
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Crystal structure of Era in complex with MgGDPNP, nucleotides 1506-1542 of 16S ribosomal RNA, and KsgA
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, GTPase Era, ...
著者Tu, C, Ji, X.
登録日2011-03-26
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
2ZM6
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Crystal structure of the Thermus thermophilus 30S ribosomal subunit
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Kaminishi, T, Wang, H, Kawazoe, M, Ishii, R, Schluenzen, F, Hanawa-Suetsugu, K, Wilson, D.N, Nomura, M, Takemoto, C, Shirouzu, M, Fucini, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-04-11
公開日2009-04-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of the Thermus thermophilus 30S ribosomal subunit
To be Published
2YKR
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30S ribosomal subunit with RsgA bound in the presence of GMPPNP
分子名称: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Guo, Q, Yuan, Y, Xu, Y, Feng, B, Liu, L, Chen, K, Lei, J, Gao, N.
登録日2011-05-30
公開日2011-08-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献Structural Basis for the Function of a Small Gtpase Rsga on the 30S Ribosomal Subunit Maturation Revealed by Cryoelectron Microscopy.
Proc.Natl.Acad.Sci.USA, 108, 2011
2HHH
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Crystal structure of kasugamycin bound to the 30S ribosomal subunit
分子名称: (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S ribosomal RNA, 30S ribosomal protein S10, ...
著者Schluenzen, F.
登録日2006-06-28
公開日2006-09-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
Nat.Struct.Mol.Biol., 13, 2006
3R9W
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Crystal structure of Era in complex with MgGDPNP and nucleotides 1506-1542 of 16S ribosomal RNA
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, CALCIUM ION, ...
著者Tu, C, Ji, X.
登録日2011-03-26
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
2E5L
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A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine- Dalgarno interaction
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Kaminishi, T, Wilson, D.N, Takemoto, C, Harms, J.M, Kawazoe, M, Schluenzen, F, Hanawa-Suetsugu, K, Shirouzu, M, Fucini, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-12-21
公開日2007-05-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction
Structure, 15, 2007
5F8K
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Crystal structure of the Bac7(1-16) antimicrobial peptide bound to the Thermus thermophilus 70S ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Seefeldt, A.C, Graf, M, Perebaskine, N, Nguyen, F, Arenz, S, Mardirossian, M, Scocchi, M, Wilson, D.N, Innis, C.A.
登録日2015-12-09
公開日2016-02-03
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Nucleic Acids Res., 44, 2016
5FCJ
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Structure of the anisomycin-containing uL3 W255C mutant 80S yeast ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Mailliot, J, Garreau de Loubresse, N, Yusupova, G, Dinman, J.D, Yusupov, M.
登録日2015-12-15
公開日2016-05-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency.
J.Mol.Biol., 428, 2016

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