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PDB: 167 件

7MD2
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The F1 region of ammocidin-bound Saccharomyces cerevisiae ATP synthase
分子名称: (3~{E},5~{Z},7~{E},9~{R},10~{S},11~{E},13~{E},15~{E},17~{R},18~{S},20~{S})-20-[(1~{R})-1-[(2~{S},3~{R},4~{R},5~{S},6~{R})-5-[(2~{S},4~{S},5~{S},6~{R})-5-[(2~{S},4~{R},5~{R},6~{R})-4,6-dimethyl-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-methyl-4-oxidanyl-oxan-2-yl]oxy-3-methoxy-6-(3-methoxypropyl)-5-methyl-2,4-bis(oxidanyl)oxan-2-yl]ethyl]-5,18-dimethoxy-3,7,9,11,13,15-hexamethyl-10-[(2~{R},3~{S},4~{R},5~{R},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-17-oxidanyl-1-oxacycloicosa-3,5,7,11,13,15-hexaen-2-one, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ...
著者Guo, H, Rubinstein, J.L.
登録日2021-04-03
公開日2021-08-11
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia
Biorxiv, 2021
7MD3
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The F1 region of apoptolidin-bound Saccharomyces cerevisiae ATP synthase
分子名称: (3~{E},5~{E},7~{E},9~{R},10~{R},11~{E},13~{E},17~{S},18~{S},20~{S})-18-methoxy-20-[(~{R})-[(2~{R},3~{R},4~{S},5~{R},6~{R})-6-[(2~{R})-3-methoxy-2-[(2~{R},4~{S},5~{S},6~{S})-5-[(2~{S},4~{R},5~{R},6~{R})-4-methoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-4,6-dimethyl-4-oxidanyl-oxan-2-yl]oxy-propyl]-3,5-dimethyl-2,4-bis(oxidanyl)oxan-2-yl]-oxidanyl-methyl]-10-[(2~{R},3~{S},4~{S},5~{R},6~{S})-5-methoxy-6-methyl-3,4-bis(oxidanyl)oxan-2-yl]oxy-3,5,7,9,13-pentamethyl-17-oxidanyl-1-oxacycloicosa-3,5,7,11,13-pentaen-2-one, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ...
著者Guo, H, Rubinstein, J.L.
登録日2021-04-03
公開日2021-08-11
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia
Biorxiv, 2021
4ASU
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F1-ATPase in which all three catalytic sites contain bound nucleotide, with magnesium ion released in the Empty site
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL, ...
著者Rees, D.M, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
登録日2012-05-03
公開日2012-06-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Evidence of a New Catalytic Intermediate in the Pathway of ATP Hydrolysis by F1-ATPase from Bovine Heart Mitochondria.
Proc.Natl.Acad.Sci.USA, 109, 2012
3FKS
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Yeast F1 ATPase in the absence of bound nucleotides
分子名称: ATP synthase subunit alpha, mitochondrial, ATP synthase subunit beta, ...
著者Kabaleeswaran, V, Symersky, J, Shen, H, Walker, J.E, Leslie, A.G.W, Mueller, D.M.
登録日2008-12-17
公開日2009-03-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.587 Å)
主引用文献Asymmetric structure of the yeast f1 ATPase in the absence of bound nucleotides.
J.Biol.Chem., 284, 2009
6F5D
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Trypanosoma brucei F1-ATPase
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP synthase gamma subunit, ATP synthase subunit alpha, ...
著者Montgomery, M.G, Gahura, O, Leslie, A.G.W, Zikova, A, Walker, J.E.
登録日2017-12-01
公開日2018-02-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献ATP synthase fromTrypanosoma bruceihas an elaborated canonical F1-domain and conventional catalytic sites.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4YXW
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Bovine heart mitochondrial F1-ATPase inhibited by AMP-PNP and ADP in the presence of thiophosphate.
分子名称: ATP synthase subunit alpha, mitochondrial, ATP synthase subunit beta, ...
著者Bason, J.V, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
登録日2015-03-23
公開日2015-05-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How release of phosphate from mammalian F1-ATPase generates a rotary substep.
Proc.Natl.Acad.Sci.USA, 112, 2015
2CK3
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Azide inhibited bovine F1-ATPase
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL, ...
著者Bowler, M.W, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
登録日2006-04-10
公開日2006-05-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献How Azide Inhibits ATP Hydrolysis by the F-Atpases.
Proc.Natl.Acad.Sci.USA, 103, 2006
1E79
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Bovine F1-ATPase inhibited by DCCD (dicyclohexylcarbodiimide)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP SYNTHASE ALPHA CHAIN HEART ISOFORM, ...
著者Gibbons, C, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
登録日2000-08-25
公開日2000-11-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of the Central Stalk in Bovine F(1)-ATPase at 2.4 A Resolution.
Nat.Struct.Biol., 7, 2000
2HLD
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Crystal structure of yeast mitochondrial F1-ATPase
分子名称: ATP synthase alpha chain, mitochondrial, ATP synthase beta chain, ...
著者Kabaleeswaran, V, Puri, N, Walker, J.E, Leslie, A.G, Mueller, D.M.
登録日2006-07-06
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Novel features of the rotary catalytic mechanism revealed in the structure of yeast F(1) ATPase.
Embo J., 25, 2006
5LQY
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Structure of F-ATPase from Pichia angusta, in state2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase OSCP subunit, ...
著者Vinothkumar, K.R, Montgomery, M.G, Liu, S, Walker, J.E.
登録日2016-08-17
公開日2016-11-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Structure of the mitochondrial ATP synthase fromPichia angustadetermined by electron cryo-microscopy.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5LQX
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Structure of F-ATPase from Pichia angusta, state3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase AAP1 subunit, ...
著者Vinothkumar, K.R, Montgomery, M.G, Liu, S, Walker, J.E.
登録日2016-08-17
公開日2016-11-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Structure of the mitochondrial ATP synthase fromPichia angustadetermined by electron cryo-microscopy.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
2JDI
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Ground state structure of F1-ATPase from bovine heart mitochondria (Bovine F1-ATPase crystallised in the absence of azide)
分子名称: ATP SYNTHASE DELTA CHAIN, ATP SYNTHASE EPSILON CHAIN, ATP SYNTHASE GAMMA CHAIN, ...
著者Bowler, M.W, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
登録日2007-01-09
公開日2007-03-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ground State Structure of F1-ATPase from Bovine Heart Mitochondria at 1.9 A Resolution
J.Biol.Chem., 282, 2007
8KHF
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Structure of the human ATP synthase bound to bedaquiline (membrane domain)
分子名称: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ...
著者Lai, Y, Zhang, Y.
登録日2023-08-21
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structure of Mycobacterium tuberculosis ATP synthase
To Be Published
1H8E
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(ADP.AlF4)2(ADP.SO4) bovine F1-ATPase (all three catalytic sites occupied)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BOVINE MITOCHONDRIAL F1-ATPASE, GLYCEROL, ...
著者Menz, R.I, Walker, J.E, Leslie, A.G.W.
登録日2001-02-02
公開日2001-08-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Bovine Mitochondrial F1-ATPase with Nucleotide Bound to All Three Catalytic Sites: Implications for the Mechanism of Rotary Catalysis
Cell(Cambridge,Mass.), 106, 2001
8KI3
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Structure of the human ATP synthase bound to bedaquiline (composite)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ...
著者Lai, Y, Zhang, Y, Gong, H.
登録日2023-08-22
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structure of Mycobacterium tuberculosis ATP synthase
To Be Published
6J5I
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Cryo-EM structure of the mammalian DP-state ATP synthase
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit epsilon, ...
著者Gu, J, Zhang, L, Yi, J, Yang, M.
登録日2019-01-11
公開日2019-06-26
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1.
Science, 364, 2019
3ZIA
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BU of 3zia by Molmil
The structure of F1-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF1
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Robinson, G.C, Bason, J.V, Montgomery, M.G, Fearnley, I.M, Mueller, D.M, Leslie, A.G.W, Walker, J.E.
登録日2013-01-07
公開日2013-02-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Structure of F1-ATPase from Saccharomyces Cerevisiae Inhibited by its Regulatory Protein If1.
Open Biol., 3, 2013
3ZRY
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Rotor architecture in the F(1)-c(10)-ring complex of the yeast F-ATP synthase
分子名称: ATP SYNTHASE CATALYTIC SECTOR F1 EPSILON SUBUNIT, ATP SYNTHASE SUBUNIT 9, MITOCHONDRIAL, ...
著者Giraud, M.-F, Dautant, A.
登録日2011-06-21
公開日2012-01-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献Rotor Architecture in the Yeast and Bovine F(1)-C-Ring Complexes of F-ATP Synthase.
J.Struct.Biol., 177, 2012
6B8H
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Mosaic model of yeast mitochondrial ATP synthase monomer
分子名称: AATP synthase subunit g, ATP synthase catalytic sector F1 epsilon subunit, ATP synthase protein 8, ...
著者Guo, H, Bueler, S.A, Rubinstein, J.L.
登録日2017-10-07
公開日2018-01-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Atomic model for the dimeric FO region of mitochondrial ATP synthase.
Science, 358, 2017
6J5K
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Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit alpha, ...
著者Gu, J, Zhang, L, Yi, J, Yang, M.
登録日2019-01-11
公開日2019-06-26
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1.
Science, 364, 2019
5FIK
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Bovine mitochondrial ATP synthase state 3a
分子名称: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ...
著者Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L.
登録日2015-09-28
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
6J5J
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Cryo-EM structure of the mammalian E-state ATP synthase
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit epsilon, ...
著者Gu, J, Zhang, L, Yi, J, Yang, M.
登録日2019-01-11
公開日2019-06-26
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1.
Science, 364, 2019
6CP6
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Monomer yeast ATP synthase (F1Fo) reconstituted in nanodisc.
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ...
著者Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M.
登録日2018-03-13
公開日2018-04-11
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane.
Science, 360, 2018
5FIL
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Bovine mitochondrial ATP synthase state 3b
分子名称: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ...
著者Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L.
登録日2015-09-28
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.1 Å)
主引用文献Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
5FIJ
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Bovine mitochondrial ATP synthase state 2c
分子名称: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ...
著者Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L.
登録日2015-09-28
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015

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