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PDB: 125 件
8VAP
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BU of 8vap by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Fully-Open conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
著者Landeck, J.T, Kelch, B.A.
登録日2023-12-11
公開日2024-03-27
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAM
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BU of 8vam by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Semi-Open conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
著者Landeck, J.T, Kelch, B.A.
登録日2023-12-11
公開日2024-03-27
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAS
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BU of 8vas by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in an Altered-Collar conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
著者Landeck, J.T, Kelch, B.A.
登録日2023-12-11
公開日2024-03-27
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
5G48
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BU of 5g48 by Molmil
H.pylori Beta clamp in complex with Diflunisal
分子名称: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, DNA POLYMERASE III SUBUNIT BETA
著者Pandey, P, Gourinath, S.
登録日2016-05-06
公開日2017-06-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Targeting the beta-clamp in Helicobacter pylori with FDA-approved drugs reveals micromolar inhibition by diflunisal.
FEBS Lett., 591, 2017
8VAT
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BU of 8vat by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Open-RNAp/t conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
著者Landeck, J.T, Kelch, B.A.
登録日2023-12-11
公開日2024-03-27
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8VAN
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BU of 8van by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in an Initial-Binding conformation
分子名称: Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ...
著者Landeck, J.T, Pajak, J, Kelch, B.A.
登録日2023-12-11
公開日2024-03-27
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 300, 2024
8DJ6
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BU of 8dj6 by Molmil
Sliding-clamp-ImuB peptide
分子名称: ACETATE ION, Beta sliding clamp, FORMIC ACID, ...
著者Kapur, M.K, Gray, O.J, Honzatko, R.H, Nelson, S.N.
登録日2022-06-30
公開日2023-07-26
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Interaction of sliding clamp with mycobacterial polymerases
To Be Published
8DT6
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BU of 8dt6 by Molmil
Crystal Structure of DNA Polymerase III beta subunit from Elizabethkingia anophelis
分子名称: Beta sliding clamp, CALCIUM ION, CHLORIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-07-25
公開日2022-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structure of DNA Polymerase III beta subunit from Elizabethkingia anophelis
to be published
5FKW
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BU of 5fkw by Molmil
cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon)
分子名称: DNA POLYMERASE III ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ...
著者Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
登録日2015-10-20
公開日2015-11-25
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
5FXT
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BU of 5fxt by Molmil
Crystal Structure of Helicobacter pylori beta clamp in complex with Carprofen
分子名称: (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, DNA POLYMERASE III SUBUNIT BETA
著者Pandey, P, Gourinath, S.
登録日2016-03-02
公開日2017-08-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization.
Antibiotics (Basel), 7, 2018
5G4Q
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BU of 5g4q by Molmil
H.pylori Beta clamp in complex with 5-chloroisatin
分子名称: 5-chloro-1H-indole-2,3-dione, DNA POLYMERASE III SUBUNIT BETA
著者Pandey, P, Gourinath, S.
登録日2016-05-16
公開日2017-06-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization.
Antibiotics (Basel), 7, 2018
6E8E
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BU of 6e8e by Molmil
Crystal structure of the Escherichia coli sliding clamp-MutL complex.
分子名称: Beta sliding clamp,DNA mismatch repair protein MutL, GLYCEROL, SULFATE ION
著者Guarne, A, Almawi, A.W.
登録日2018-07-28
公開日2019-05-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Binding of the regulatory domain of MutL to the sliding beta-clamp is species specific.
Nucleic Acids Res., 47, 2019
6E8D
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BU of 6e8d by Molmil
Crystal structure of the Bacillus subtilis sliding clamp-MutL complex.
分子名称: Beta sliding clamp,DNA mismatch repair protein MutL, GLYCEROL
著者Guarne, A, Almawi, A.W.
登録日2018-07-28
公開日2019-05-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Binding of the regulatory domain of MutL to the sliding beta-clamp is species specific.
Nucleic Acids Res., 47, 2019
6FVM
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BU of 6fvm by Molmil
Mutant DNA polymerase sliding clamp from Escherichia coli with bound P7 peptide
分子名称: Beta sliding clamp, CALCIUM ION, GLYCEROL, ...
著者Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D.
登録日2018-03-04
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.631 Å)
主引用文献Peptide Interactions on Bacterial Sliding Clamps.
Acs Infect Dis., 2019
6FVL
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BU of 6fvl by Molmil
DNA polymerase sliding clamp from Escherichia coli with bound P7 peptide
分子名称: Beta sliding clamp, GLYCEROL, P7 peptide, ...
著者Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D.
登録日2018-03-04
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.975 Å)
主引用文献Peptide Interactions on Bacterial Sliding Clamps.
Acs Infect Dis., 2019
6DM6
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BU of 6dm6 by Molmil
Structure of DNA polymerase III subunit beta from Rickettsia conorii in complex with a natural product
分子名称: Beta sliding clamp, Natural product peptide
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-06-04
公開日2019-06-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of DNA polymerase III subunit beta from Rickettsia conorii in complex with a natural product
to be published
6DLK
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BU of 6dlk by Molmil
Crystal structure of DNA polymerase III subunit beta from Rickettsia rickettsii
分子名称: 1,2-ETHANEDIOL, Beta sliding clamp
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-06-01
公開日2018-10-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of DNA polymerase III subunit beta from Rickettsia rickettsii
to be published
6DLY
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BU of 6dly by Molmil
Crystal structure of DNA polymerase III subunit beta from Mycobacterium marinum in complex with a natural product
分子名称: 1,2-ETHANEDIOL, Beta sliding clamp, Natural product peptide
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-06-04
公開日2019-06-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of DNA polymerase III subunit beta from Mycobacterium marinum in complex with a natural product
to be published
6FVO
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BU of 6fvo by Molmil
Mutant DNA polymerase sliding clamp from Mycobacterium tuberculosis with bound P7 peptide
分子名称: Beta sliding clamp, CALCIUM ION, P7 peptide
著者Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D.
登録日2018-03-04
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.689 Å)
主引用文献Peptide Interactions on Bacterial Sliding Clamps.
Acs Infect Dis., 2019
6FVN
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BU of 6fvn by Molmil
DNA polymerase sliding clamp from Mycobacterium tuberculosis with bound P7 peptide
分子名称: Beta sliding clamp, P7 peptide
著者Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D.
登録日2018-03-04
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.142 Å)
主引用文献Peptide Interactions on Bacterial Sliding Clamps.
Acs Infect Dis., 2019
7AZ5
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BU of 7az5 by Molmil
DNA polymerase sliding clamp from Escherichia coli with peptide 47 bound
分子名称: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, Peptide 47, ...
著者Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y.
登録日2020-11-16
公開日2021-12-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
7AZG
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BU of 7azg by Molmil
DNA polymerase sliding clamp from Escherichia coli with peptide 4 bound
分子名称: Beta sliding clamp, Peptide 4
著者Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y.
登録日2020-11-16
公開日2021-12-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
7AZL
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BU of 7azl by Molmil
DNA polymerase sliding clamp from Escherichia coli with peptide 38 bound
分子名称: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y.
登録日2020-11-16
公開日2021-12-01
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
7AZ7
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BU of 7az7 by Molmil
DNA polymerase sliding clamp from Escherichia coli with peptide 37 bound
分子名称: Beta sliding clamp, FORMIC ACID, PENTAETHYLENE GLYCOL, ...
著者Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y.
登録日2020-11-16
公開日2021-12-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
7AZ6
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BU of 7az6 by Molmil
DNA polymerase sliding clamp from Escherichia coli with peptide 36 bound
分子名称: ACETATE ION, Beta sliding clamp, CHLORIDE ION, ...
著者Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y.
登録日2020-11-16
公開日2021-12-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021

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件を2024-07-10に公開中

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