Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 43 件
7PUO
DownloadVisualize
BU of 7puo by Molmil
Structure of a fused 4-OT variant engineered for asymmetric Michael addition reactions
分子名称: 2-hydroxymuconate tautomerase,Chains: A,B,C,D,E,F,2-hydroxymuconate tautomerase, CHLORIDE ION, GLYCEROL
著者Rozeboom, H.J, Thunnissen, A.M.W.H, Poelarends, G.J.
登録日2021-09-30
公開日2022-01-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Gene Fusion and Directed Evolution to Break Structural Symmetry and Boost Catalysis by an Oligomeric C-C Bond-Forming Enzyme.
Angew.Chem.Int.Ed.Engl., 61, 2022
1S0Y
DownloadVisualize
BU of 1s0y by Molmil
The structure of trans-3-chloroacrylic acid dehalogenase, covalently inactivated by the mechanism-based inhibitor 3-bromopropiolate at 2.3 Angstrom resolution
分子名称: MALONIC ACID, alpha-subunit of trans-3-chloroacrylic acid dehalogenase, beta-subunit of trans-3-chloroacrylic acid dehalogenase
著者de Jong, R.M, Brugman, W, Poelarends, G.J, Whitman, C.P, Dijkstra, B.W.
登録日2004-01-05
公開日2004-02-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily
J.Biol.Chem., 279, 2004
4X1C
DownloadVisualize
BU of 4x1c by Molmil
Crystal structure of 4-OT from Pseudomonas putida mt-2 with an enamine adduct on the N-terminal proline at 1.7 Angstrom resolution
分子名称: 2-hydroxymuconate tautomerase, COBALT HEXAMMINE(III)
著者Thunnissen, A.M.W.H, Poddar, H.
登録日2014-11-24
公開日2015-03-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evidence for the Formation of an Enamine Species during Aldol and Michael-type Addition Reactions Promiscuously Catalyzed by 4-Oxalocrotonate Tautomerase.
Chembiochem, 16, 2015
7M59
DownloadVisualize
BU of 7m59 by Molmil
Crystal structure of N2, a member of 4-oxalocrotonate tautomerase (4-OT) family
分子名称: Tautomerase domain-containing protein
著者Medellin, B.P, Moreno, R.Y, Zhang, Y.J.
登録日2021-03-23
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications.
Biochemistry, 60, 2021
6OGM
DownloadVisualize
BU of 6ogm by Molmil
Crystal structure of apo unFused 4-OT
分子名称: 4-oxalocrotonate tautomerase, GLYCEROL
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2019-04-03
公開日2020-02-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.865 Å)
主引用文献Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 58, 2019
7XUY
DownloadVisualize
BU of 7xuy by Molmil
Crystal structure of 5-chloro-2-hydroxymuconate tautomerase CnbG
分子名称: Tautomerase
著者Ma, H.L, Li, D.F.
登録日2022-05-20
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural insights into the substrate specificity of 5-chloro-2-hydroxymuconate tautomerase CnbG.
Biochem.Biophys.Res.Commun., 620, 2022
2FM7
DownloadVisualize
BU of 2fm7 by Molmil
Evolution of Enzymatic Activity in the Tautomerase Superfamily: Mechanistic and Structural Consequences of the L8R Mutation in 4-Oxalocrotonate Tautomerase
分子名称: 4-Oxalocrotonate Tautomerase, CHLORIDE ION
著者Almrud, J.J, Hackert, M.L.
登録日2006-01-08
公開日2006-09-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase
Biochemistry, 45, 2006
1BJP
DownloadVisualize
BU of 1bjp by Molmil
CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE INACTIVATED BY 2-OXO-3-PENTYNOATE AT 2.4 ANGSTROMS RESOLUTION
分子名称: 2-OXO-3-PENTENOIC ACID, 4-OXALOCROTONATE TAUTOMERASE
著者Taylor, A.B, Czerwinski, R.M, Johnson Junior, W.H, Whitman, C.P, Hackert, M.L.
登録日1998-06-26
公開日1998-12-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of 4-oxalocrotonate tautomerase inactivated by 2-oxo-3-pentynoate at 2.4 A resolution: analysis and implications for the mechanism of inactivation and catalysis.
Biochemistry, 37, 1998
1OTF
DownloadVisualize
BU of 1otf by Molmil
4-OXALOCROTONATE TAUTOMERASE-TRICLINIC CRYSTAL FORM
分子名称: 4-OXALOCROTONATE TAUTOMERASE
著者Subramanya, H.S, Roper, D.I, Dauter, Z, Dodson, E.J, Davies, G.J, Wilson, K.S, Wigley, D.B.
登録日1995-11-09
公開日1996-04-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Enzymatic ketonization of 2-hydroxymuconate: specificity and mechanism investigated by the crystal structures of two isomerases.
Biochemistry, 35, 1996
4X19
DownloadVisualize
BU of 4x19 by Molmil
Crystal structure of native 4-OT from Pseudomonas putida mt-2 at 1.94 Angstrom
分子名称: 2-hydroxymuconate tautomerase, COBALT HEXAMMINE(III)
著者Thunnissen, A.M.W.H, Poddar, H.
登録日2014-11-24
公開日2015-03-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.944 Å)
主引用文献Evidence for the Formation of an Enamine Species during Aldol and Michael-type Addition Reactions Promiscuously Catalyzed by 4-Oxalocrotonate Tautomerase.
Chembiochem, 16, 2015
3RY0
DownloadVisualize
BU of 3ry0 by Molmil
Crystal structure of TomN, a 4-Oxalocrotonate Tautomerase homologue in Tomaymycin biosynthetic pathway
分子名称: Putative tautomerase
著者Zhang, Y, Yan, W.P, Li, W.Z, Whitman, C.P.
登録日2011-05-10
公開日2011-08-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Kinetic, Crystallographic, and Mechanistic Characterization of TomN: Elucidation of a Function for a 4-Oxalocrotonate Tautomerase Homologue in the Tomaymycin Biosynthetic Pathway.
Biochemistry, 50, 2011
5TIG
DownloadVisualize
BU of 5tig by Molmil
CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE INACTIVATED BY BrHPD
分子名称: (3E)-5-hydroxy-2-oxopent-3-enoic acid, 2-hydroxymuconate tautomerase
著者Zhang, Y, Li, W, Stack, T.
登録日2016-10-02
公開日2018-02-21
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates.
Biochemistry, 57, 2018
5CLO
DownloadVisualize
BU of 5clo by Molmil
Crystal structure of a 4-oxalocrotonate tautomerase mutant in complex with nitrostyrene at 2.3 Angstrom
分子名称: 2-hydroxymuconate tautomerase, trans beta nitrostyrene
著者Thunnissen, A.M.W.H, Poddar, H.
登録日2015-07-16
公開日2016-03-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases.
Nat Commun, 7, 2016
5CLN
DownloadVisualize
BU of 5cln by Molmil
Crystal structure of a 4-oxalocrotonate tautomerase mutant at 2.7 Angstrom
分子名称: 2-hydroxymuconate tautomerase
著者Thunnissen, A.M.W.H, Poddar, H.
登録日2015-07-16
公開日2016-03-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases.
Nat Commun, 7, 2016
6FPS
DownloadVisualize
BU of 6fps by Molmil
Crystal structure of 4-oxalocrotonate tautomerase triple mutant L8Y/M45Y/F50A
分子名称: 2-hydroxymuconate tautomerase, GLYCEROL, PHOSPHATE ION
著者Pijning, T, Thunnissen, A.M.W.H.
登録日2018-02-12
公開日2019-03-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Enantioselective Synthesis of Pharmaceutically Active gamma-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions.
ACS Catal, 9, 2019
4FDX
DownloadVisualize
BU of 4fdx by Molmil
Kinetic and structural characterization of the 4-oxalocrotonate tautomerase isozymes from Methylibium petroleiphilum
分子名称: 4-oxalocrotonase tautomerase isozyme
著者Terrell, C.R, Hoffman, D.W, Whitman, C.P.
登録日2012-05-29
公開日2013-06-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural and kinetic characterization of two 4-oxalocrotonate tautomerases in Methylibium petroleiphilum strain PM1.
Arch.Biochem.Biophys., 537, 2013
4FAZ
DownloadVisualize
BU of 4faz by Molmil
Kinetic and structural characterization of the 4-oxalocrotonate tautomerase isozymes from Methylibium petroleiphilum
分子名称: 4-oxalocrotonate isomerase protein, SULFATE ION
著者Terrell, C.R, Hoffman, D.W, Whitman, C.P.
登録日2012-05-22
公開日2013-06-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structural and kinetic characterization of two 4-oxalocrotonate tautomerases in Methylibium petroleiphilum strain PM1.
Arch.Biochem.Biophys., 537, 2013
6VVR
DownloadVisualize
BU of 6vvr by Molmil
Q0 fused 4-OT wild type symmetric trimer
分子名称: Tautomerase
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2020-02-18
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 59, 2020
6BGN
DownloadVisualize
BU of 6bgn by Molmil
Crystal Structure of 4-Oxalocrotonate Tautomerase After Incubation with 5-Fluoro-2-hydroxy-2,4-pentadienoate
分子名称: 2-hydroxymuconate tautomerase, 5-fluoranyl-2-oxidanylidene-pentanoic acid, GLYCEROL, ...
著者Zhang, Y, Li, W, Stack, T.
登録日2017-10-29
公開日2018-02-21
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates.
Biochemistry, 57, 2018
2X4K
DownloadVisualize
BU of 2x4k by Molmil
Crystal structure of SAR1376, a putative 4-oxalocrotonate tautomerase from the methicillin-resistant Staphylococcus aureus (MRSA)
分子名称: 4-OXALOCROTONATE TAUTOMERASE, ACETATE ION, PHOSPHATE ION, ...
著者Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H.
登録日2010-02-01
公開日2010-07-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
5UNQ
DownloadVisualize
BU of 5unq by Molmil
Crystal Structure of Pt0534 Inactivated by 2-Oxo-3-pentynoate
分子名称: Putative tautomerase
著者LeVieux, J, Baas, B.J, Zhang, Y.J, Whitman, C.P.
登録日2017-01-31
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.976 Å)
主引用文献A global view of structure-function relationships in the tautomerase superfamily.
J. Biol. Chem., 293, 2018
6GHW
DownloadVisualize
BU of 6ghw by Molmil
Substituting the prolines of 4-oxalocrotonate tautomerase with non-canonical analogue (2S)-3,4-dehydroproline
分子名称: 2-hydroxymuconate tautomerase, CALCIUM ION
著者Pavkov-Keller, T, Lukesch, M.S, Wiltschi, B, Gruber, K.
登録日2018-05-09
公開日2019-03-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Substituting the catalytic proline of 4-oxalocrotonate tautomerase with non-canonical analogues reveals a finely tuned catalytic system.
Sci Rep, 9, 2019
6VVW
DownloadVisualize
BU of 6vvw by Molmil
W0 fused 4-OT wild type symmetric trimer
分子名称: Tautomerase
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2020-02-18
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 59, 2020
6BLM
DownloadVisualize
BU of 6blm by Molmil
Crystal Structure of Native Fused 4-OT
分子名称: 4-oxalocrotonate tautomerase
著者LeVieux, J, Baas, B.J, Zhang, Y.J, Whitman, C.P.
登録日2017-11-10
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.488 Å)
主引用文献A global view of structure-function relationships in the tautomerase superfamily.
J. Biol. Chem., 293, 2018
3ABF
DownloadVisualize
BU of 3abf by Molmil
Crystal Structure of a 4-Oxalocrotonate Tautomerase Homologue (TTHB242)
分子名称: 4-oxalocrotonate tautomerase, SULFATE ION
著者Kida, H, Miki, K.
登録日2009-12-10
公開日2010-12-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal Structure of a 4-Oxalocrotonate Tautomerase Homologue (TTHB242) from Thermus thermophilus HB8
To be Published

 

12>

224201

件を2024-08-28に公開中

PDB statisticsPDBj update infoContact PDBjnumon