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PDB: 142 件
4S10
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Gelsolin nanobody shielding mutant plasma gelsolin from furin proteolysis
分子名称: CALCIUM ION, GELSOLIN NANOBODY, Gelsolin
著者Wongsantichon, J, Robinson, R.C, Gettemans, J.
登録日2015-01-07
公開日2015-06-03
実験手法X-RAY DIFFRACTION (2.614 Å)
主引用文献An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model.
Hum.Mol.Genet., 24, 2015
1SVQ
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BU of 1svq by Molmil
STRUCTURE OF SEVERIN DOMAIN 2 IN SOLUTION
分子名称: SEVERIN
著者Schnuchel, A, Holak, T.A.
登録日1994-10-12
公開日1995-02-07
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Structure of severin domain 2 in solution.
J.Mol.Biol., 247, 1995
1SVY
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BU of 1svy by Molmil
SEVERIN DOMAIN 2, 1.75 ANGSTROM CRYSTAL STRUCTURE
分子名称: CALCIUM ION, SEVERIN, SODIUM ION
著者Puius, Y.A, Fedorov, E.V, Eichinger, L, Sullivan, M, Schleicher, M, Almo, S.C.
登録日1998-08-10
公開日1999-08-10
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mapping the functional surface of domain 2 in the gelsolin superfamily.
Biochemistry, 39, 2000
1SVR
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BU of 1svr by Molmil
STRUCTURE OF SEVERIN DOMAIN 2 IN SOLUTION
分子名称: SEVERIN
著者Schnuchel, A, Holak, T.A.
登録日1994-10-12
公開日1995-02-07
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Structure of severin domain 2 in solution.
J.Mol.Biol., 247, 1995
2FH3
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BU of 2fh3 by Molmil
C-terminal half of gelsolin soaked in low calcium at pH 8
分子名称: CALCIUM ION, Gelsolin
著者Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C.
登録日2005-12-23
公開日2006-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Calcium ion exchange in crystalline gelsolin
J.Mol.Biol., 357, 2006
2FGH
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ATP bound gelsolin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, gelsolin
著者Ma, Q, Robinson, R.C, Burtnick, L.D, Urosev, D.
登録日2005-12-22
公開日2006-04-18
最終更新日2017-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structure of gelsolin bound to ATP
J.Mol.Biol., 357, 2006
2FH2
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C-terminal half of gelsolin soaked in EGTA at pH 4.5
分子名称: CALCIUM ION, Gelsolin
著者Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C.
登録日2005-12-23
公開日2006-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Calcium ion exchange in crystalline gelsolin
J.Mol.Biol., 357, 2006
2FH4
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C-terminal half of gelsolin soaked in EGTA at pH 8
分子名称: Gelsolin
著者Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C.
登録日2005-12-23
公開日2006-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Calcium ion exchange in crystalline gelsolin
J.Mol.Biol., 357, 2006
2FH1
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C-terminal half of gelsolin soaked in low calcium at pH 4.5
分子名称: CALCIUM ION, Gelsolin
著者Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C.
登録日2005-12-23
公開日2006-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Calcium ion exchange in crystalline gelsolin
J.Mol.Biol., 357, 2006
1P8X
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The Calcium-Activated C-terminal half of gelsolin
分子名称: CALCIUM ION, Gelsolin precursor, plasma
著者Narayan, K, Burtnick, L.D, Robinson, R.C.
登録日2003-05-08
公開日2003-10-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Activation in isolation: Exposure of the actin-binding site in the C-terminal half of gelsolin does not require actin
FEBS LETT., 552, 2003
1NPH
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Gelsolin Domains 4-6 in Active, Actin Free Conformation Identifies Sites of Regulatory Calcium Ions
分子名称: CALCIUM ION, Gelsolin
著者Kolappan, S, Gooch, J.T, Weeds, A.G, McLaughlin, P.J.
登録日2003-01-17
公開日2003-05-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Gelsolin Domains 4-6 in Active, Actin-Free Conformation Identifies Sites of Regulatory Calcium Ions
J.Mol.Biol., 329, 2003
3FG7
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The crystal structure of villin domain 6
分子名称: Villin-1
著者Wang, H, Burtnick, L.D, Robinson, R.C.
登録日2008-12-05
公開日2009-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Helix-straightening as an activation mechanism in the gelsolin superfamily of actin regulatory proteins
J.Biol.Chem., 284, 2009
3FFN
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Crystal structure of calcium-free human gelsolin
分子名称: Gelsolin
著者Chumnarnsilpa, S, Robinson, R.C, Burtnick, L.D.
登録日2008-12-04
公開日2009-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin.
Proc.Natl.Acad.Sci.USA, 106, 2009
3FG6
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BU of 3fg6 by Molmil
Structure of the C-terminus of Adseverin
分子名称: Adseverin, CALCIUM ION
著者Robinson, R.C.
登録日2008-12-05
公開日2009-08-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The crystal structure of the C-terminus of adseverin reveals the actin-binding interface.
Proc.Natl.Acad.Sci.USA, 106, 2009
6JEH
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BU of 6jeh by Molmil
Crystal structure of calcium free human gelsolin amyloid mutant D187Y
分子名称: Gelsolin
著者Zorgati, H, Robinson, R.C.
登録日2019-02-05
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The role of gelsolin domain 3 in familial amyloidosis (Finnish type).
Proc.Natl.Acad.Sci.USA, 116, 2019
6JCO
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Crystal structure of calcium free human gelsolin amyloid mutant D187N
分子名称: Gelsolin
著者Zorgati, H, Robinson, R.C.
登録日2019-01-29
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献The role of gelsolin domain 3 in familial amyloidosis (Finnish type).
Proc.Natl.Acad.Sci.USA, 116, 2019
6JEG
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Crystal structure of calcium free human gelsolin amyloid mutant G167R
分子名称: GLYCEROL, Gelsolin
著者Zorgati, H, Robinson, R.C.
登録日2019-02-05
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.975 Å)
主引用文献The role of gelsolin domain 3 in familial amyloidosis (Finnish type).
Proc.Natl.Acad.Sci.USA, 116, 2019
6H1F
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BU of 6h1f by Molmil
Structure of the nanobody-stabilized gelsolin D187N variant (second domain)
分子名称: Gelsolin, THIOCYANATE ION, gelsolin nanobody, ...
著者Hassan, A, Milani, M, Mastrangelo, E, de Rosa, M.
登録日2018-07-11
公開日2019-01-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
8HR0
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BU of 8hr0 by Molmil
The complex structure of COPII coat with HCoV-OC43 DD sorting motif
分子名称: HCoV-OC43, Protein transport protein Sec23A, Protein transport protein Sec24A, ...
著者Ma, W.F, Nan, Y.N, Yang, M.R, Li, Y.Q.
登録日2022-12-14
公開日2023-12-20
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Tighter ER retention of SARS-CoV-2 Omicron spike caused by a constellation of folding disruptive mutations
To Be Published
1M2V
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BU of 1m2v by Molmil
Crystal Structure of the yeast Sec23/24 heterodimer
分子名称: ZINC ION, protein transport protein SEC23, protein transport protein SEC24
著者Bi, X, Corpina, R.A, Goldberg, J.
登録日2002-06-25
公開日2002-09-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat
Nature, 419, 2002
5VNG
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Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal II sorting motif
分子名称: C-terminal ILE-ILE, Protein transport protein Sec23A, Protein transport protein Sec24A, ...
著者Ma, W, Goldberg, J.
登録日2017-04-30
公開日2017-07-05
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate.
Elife, 6, 2017
5KYW
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BU of 5kyw by Molmil
crystal structure of Sec23 and TANGO1 peptide3 complex
分子名称: Protein transport protein Sec23A, Protein transport protein Sec24D, TANGO1 peptide3, ...
著者Ma, W, Goldberg, J.
登録日2016-07-22
公開日2016-09-07
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coats.
Proc.Natl.Acad.Sci.USA, 113, 2016
5KYU
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BU of 5kyu by Molmil
crystal structure of Sec23 and TANGO1 peptide2 complex
分子名称: Protein transport protein Sec23A, Protein transport protein Sec24D, TANGO1 peptide2, ...
著者Ma, W, Goldberg, J.
登録日2016-07-22
公開日2016-09-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.512 Å)
主引用文献TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coats.
Proc.Natl.Acad.Sci.USA, 113, 2016
5KYY
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Crystal structure of Sec23 and TANGO1 peptide4 complex
分子名称: Protein transport protein Sec23A, Protein transport protein Sec24D, ZINC ION
著者Ma, W, Goldberg, J.
登録日2016-07-22
公開日2016-09-07
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (3.403 Å)
主引用文献TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coats.
Proc.Natl.Acad.Sci.USA, 113, 2016
5KYX
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crystal structure of Sec23 and TANGO1 peptide1 complex
分子名称: Protein transport protein Sec23A, Protein transport protein Sec24D, ZINC ION
著者Ma, W, Goldberg, J.
登録日2016-07-22
公開日2016-09-07
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (3.516 Å)
主引用文献TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coats.
Proc.Natl.Acad.Sci.USA, 113, 2016

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