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PDB: 595 件

7KW2
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Non-ribosomal didomain (holo-PCP-C) acceptor bound state, R2577G
分子名称: 4'-PHOSPHOPANTETHEINE, PCP-C didomain
著者Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J.
登録日2020-11-29
公開日2021-03-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity.
Nat Commun, 12, 2021
5EJD
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The crystal structure of holo T3CT
分子名称: 4'-PHOSPHOPANTETHEINE, GLYCEROL, TqaA
著者Zhang, J.R, Tang, Y, Zhou, J.H.
登録日2015-11-01
公開日2016-10-19
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural basis of nonribosomal peptide macrocyclization in fungi
Nat.Chem.Biol., 12, 2016
2XZ0
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The Structure of the 2:1 (Partially Occupied) Complex Between Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean) and Acyl Carrier Protein.
分子名称: 1,2-ETHANEDIOL, ACYL CARRIER PROTEIN 1, CHLOROPLASTIC, ...
著者Moche, M, Guy, J.E, Whittle, E, Lengqvist, J, Shanklin, J, Lindqvist, Y.
登録日2010-11-22
公開日2011-09-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Remote Control of Regioselectivity in Acyl-Acyl Carrier Protein-Desaturases.
Proc.Natl.Acad.Sci.USA, 108, 2011
2FQ1
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Crystal structure of the two-domain non-ribosomal peptide synthetase EntB containing isochorismate lyase and aryl-carrier protein domains
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Isochorismatase, ...
著者Drake, E.J, Nicolai, D.A, Gulick, A.M.
登録日2006-01-17
公開日2006-05-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain.
Chem.Biol., 13, 2006
5ISX
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Structure of the holo PCP-E didomain of the gramicidin S synthetase A
分子名称: 4'-PHOSPHOPANTETHEINE, GLYCEROL, Gramicidin S synthase 1
著者Chen, W.-H, Li, K, Bruner, S.D.
登録日2016-03-15
公開日2016-06-29
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (2.335 Å)
主引用文献Interdomain and Intermodule Organization in Epimerization Domain Containing Nonribosomal Peptide Synthetases.
Acs Chem.Biol., 11, 2016
5ISW
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Structure of the apo PCP-E didomain of the gramicidin S synthetase A
分子名称: GLYCEROL, Gramicidin S synthase 1
著者Chen, W.-H, Li, K, Bruner, S.D.
登録日2016-03-15
公開日2016-06-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Interdomain and Intermodule Organization in Epimerization Domain Containing Nonribosomal Peptide Synthetases.
Acs Chem.Biol., 11, 2016
6U0J
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Crosslinked Crystal Structure of Malonyl-CoA Acyl Carrier Protein Transacylase, FabD, and Acyl Carrier Protein, AcpP
分子名称: 1,2-ETHANEDIOL, Acyl carrier protein, Malonyl CoA-acyl carrier protein transacylase, ...
著者Mindrebo, J.T, Misson, L, Davis, T.D, Burkart, M.D, Noel, J.P.
登録日2019-08-14
公開日2020-07-22
最終更新日2020-10-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Interfacial plasticity facilitates high reaction rate of E. coli FAS malonyl-CoA:ACP transacylase, FabD.
Proc.Natl.Acad.Sci.USA, 117, 2020
6SGA
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Body domain of the mt-SSU assemblosome from Trypanosoma brucei
分子名称: 9S rRNA, MAGNESIUM ION, PHOSPHATE ION, ...
著者Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
登録日2019-08-03
公開日2019-09-18
最終更新日2019-09-25
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
4H2X
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Crystal structure of engineered Bradyrhizobium japonicum glycine:[carrier protein] ligase complexed with carrier protein from Agrobacterium tumefaciens and an analogue of glycyl adenylate
分子名称: 4'-PHOSPHOPANTETHEINE, 5'-O-(glycylsulfamoyl)adenosine, Amino acid--[acyl-carrier-protein] ligase 1, ...
著者Luic, M, Weygand-Durasevic, I, Ivic, N, Mocibob, M.
登録日2012-09-13
公開日2013-03-06
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Adaptation of aminoacyl-tRNA synthetase catalytic core to carrier protein aminoacylation.
Structure, 21, 2013
4H2U
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Crystal structure of Bradyrhizobium japonicum glycine:[carrier protein] ligase complexed with cognate carrier protein and ATP
分子名称: 4'-PHOSPHOPANTETHEINE, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Luic, M, Weygand-Durasevic, I, Ivic, N, Mocibob, M.
登録日2012-09-13
公開日2013-03-06
最終更新日2013-05-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Adaptation of aminoacyl-tRNA synthetase catalytic core to carrier protein aminoacylation.
Structure, 21, 2013
6RCX
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Mycobacterial 4'-phosphopantetheinyl transferase PptAb in complex with the ACP domain of PpsC.
分子名称: CACODYLATE ION, COENZYME A, MANGANESE (II) ION, ...
著者Nguyen, M.C, Mourey, L, Pedelacq, J.D.
登録日2019-04-12
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases.
Febs J., 287, 2020
6VTJ
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Structure of a thiolation-reductase di-domain from an archaeal non-ribosomal peptide synthetase
分子名称: 4'-PHOSPHOPANTETHEINE, Non-ribosomal peptide synthetase
著者Deshpande, S, Lott, J.S, Lee, T.V.
登録日2020-02-12
公開日2020-02-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural characterization of a PCP-R didomain from an archaeal nonribosomal peptide synthetase reveals novel interdomain interactions.
J.Biol.Chem., 296, 2021
4H2Y
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Crystal structure of engineered Bradyrhizobium japonicum glycine:[carrier protein] ligase complexed with carrier protein from Agrobacterium tumefaciens and ATP
分子名称: 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, Amino acid--[acyl-carrier-protein] ligase 1, ...
著者Luic, M, Weygand-Durasevic, I, Ivic, N, Mocibob, M.
登録日2012-09-13
公開日2013-03-06
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Adaptation of aminoacyl-tRNA synthetase catalytic core to carrier protein aminoacylation.
Structure, 21, 2013
4H2S
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BU of 4h2s by Molmil
Crystal structure of Bradyrhizobium japonicum glycine:[carrier protein] ligase complexed with cognate carrier protein and AMP
分子名称: 4'-PHOSPHOPANTETHEINE, ACETATE ION, ADENOSINE MONOPHOSPHATE, ...
著者Luic, M, Weygand-Durasevic, I, Ivic, N, Mocibob, M.
登録日2012-09-13
公開日2013-03-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Adaptation of aminoacyl-tRNA synthetase catalytic core to carrier protein aminoacylation.
Structure, 21, 2013
4H2V
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BU of 4h2v by Molmil
Crystal structure of Bradyrhizobium japonicum glycine:[carrier protein] ligase complexed with glycylated carrier protein
分子名称: 4'-PHOSPHOPANTETHEINE, ACETATE ION, ADENOSINE MONOPHOSPHATE, ...
著者Luic, M, Weygand-Durasevic, I, Ivic, N, Mocibob, M.
登録日2012-09-13
公開日2013-03-06
最終更新日2013-05-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Adaptation of aminoacyl-tRNA synthetase catalytic core to carrier protein aminoacylation.
Structure, 21, 2013
4H2T
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Crystal structure of Bradyrhizobium japonicum glycine:[carrier protein] ligase complexed with cognate carrier protein and an analogue of glycyl adenylate
分子名称: 4'-PHOSPHOPANTETHEINE, 5'-O-(glycylsulfamoyl)adenosine, Amino acid--[acyl-carrier-protein] ligase 1, ...
著者Luic, M, Weygand-Durasevic, I, Ivic, N, Mocibob, M.
登録日2012-09-13
公開日2013-03-06
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Adaptation of aminoacyl-tRNA synthetase catalytic core to carrier protein aminoacylation.
Structure, 21, 2013
6VTZ
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BU of 6vtz by Molmil
Structure of a thiolation-reductase di-domain from an archaeal non-ribosomal peptide synthetase
分子名称: Non-ribosomal peptide synthetase
著者Deshpande, S, Lott, J.S, Lee, T.V.
登録日2020-02-13
公開日2020-02-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural characterization of a PCP-R didomain from an archaeal nonribosomal peptide synthetase reveals novel interdomain interactions.
J.Biol.Chem., 296, 2021
4ETW
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BU of 4etw by Molmil
Structure of the Enzyme-ACP Substrate Gatekeeper Complex Required for Biotin Synthesis
分子名称: Acyl carrier protein, Pimelyl-[acyl-carrier protein] methyl ester esterase, methyl 7-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-7-oxoheptanoate
著者Agarwal, V, Nair, S.K.
登録日2012-04-24
公開日2012-10-17
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DXE
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2.52 Angstrom resolution crystal structure of the acyl-carrier-protein synthase (AcpS)-acyl carrier protein (ACP) protein-protein complex from Staphylococcus aureus subsp. aureus COL
分子名称: Acyl carrier protein, MALONATE ION, acyl-carrier-protein synthase
著者Halavaty, A.S, Minasov, G, Filippova, E.V, Dubrovska, I, Winsor, J, Shuvalova, L, Peterson, S.N, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-02-27
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献2.52 Angstrom resolution crystal structure of the acyl-carrier-protein synthase (AcpS)-acyl carrier protein (ACP) protein-protein complex from Staphylococcus aureus subsp. aureus COL
To be Published
4H2W
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BU of 4h2w by Molmil
Crystal structure of engineered Bradyrhizobium japonicum glycine:[carrier protein] ligase complexed with carrier protein from Agrobacterium tumefaciens and AMP
分子名称: 4'-PHOSPHOPANTETHEINE, ADENOSINE MONOPHOSPHATE, Amino acid--[acyl-carrier-protein] ligase 1, ...
著者Luic, M, Weygand-Durasevic, I, Ivic, N, Mocibob, M.
登録日2012-09-13
公開日2013-03-06
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Adaptation of aminoacyl-tRNA synthetase catalytic core to carrier protein aminoacylation.
Structure, 21, 2013
5ZK4
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The structure of DSZS acyltransferase with carrier protein
分子名称: DisA protein, DisD protein, N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ...
著者Miyanaga, A, Ouchi, R, Kudo, F, Eguchi, T.
登録日2018-03-23
公開日2018-06-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structural basis of protein-protein interactions between a trans-acting acyltransferase and acyl carrier protein in polyketide disorazole biosynthesis
J. Am. Chem. Soc., 140, 2018
6BUH
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Crystal structure of a membrane protein, crystal form II
分子名称: D-alanyl carrier protein, D-alanyl transfer protein DltB
著者Ma, D, Wang, Z, Xu, W.
登録日2017-12-10
公開日2018-10-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Crystal structure of a membrane-bound O-acyltransferase.
Nature, 562, 2018
6BUG
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Crystal structure of a membrane protein, crystal form I
分子名称: D-alanyl carrier protein, D-alanyl transfer protein DltB
著者Ma, D, Wang, Z, Xu, W.
登録日2017-12-10
公開日2018-10-10
最終更新日2018-10-24
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Crystal structure of a membrane-bound O-acyltransferase.
Nature, 562, 2018
8H6S
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Structure of acyltransferase VinK in complex with the loading acyl carrier protein of vicenistatin PKS
分子名称: MAGNESIUM ION, Malonyl-CoA-[acyl-carrier-protein] transacylase, N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ...
著者Kawada, K, Miyanaga, A, Chisuga, T, Kudo, F, Eguchi, T.
登録日2022-10-18
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis of Transient Interactions of Acyltransferase VinK with the Loading Acyl Carrier Protein of the Vicenistatin Modular Polyketide Synthase.
Biochemistry, 62, 2023
8G3I
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Non-ribosomal PCP-C didomain (thioether stabilised glycolic acid) acceptor bound state
分子名称: N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(2-hydroxyethyl)sulfanyl]ethyl}-beta-alaninamide, PCP-C didomain
著者Ho, Y.T.C, Izore, T, Cryle, M.J.
登録日2023-02-08
公開日2023-06-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Exploring the selectivity and engineering potential of an NRPS condensation domain involved in the biosynthesis of the thermophilic siderophore fuscachelin
Front Catal, 3, 2023

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