8DNZ
 
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8DNY
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8DO0
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8DO2
 | | Cryo-EM structure of the human Sec61 complex inhibited by cyclotriazadisulfonamide (CADA) | | 分子名称: | 9-benzyl-1,5-bis(4-methylbenzene-1-sulfonyl)-3-methylidene-1,5,9-triazacyclododecane, Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, ... | | 著者 | Park, E, Itskanov, S. | | 登録日 | 2022-07-12 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | A common mechanism of Sec61 translocon inhibition by small molecules.
Nat.Chem.Biol., 19, 2023
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8DNX
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8DO1
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8DNV
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8DO3
 | | Cryo-EM structure of the human Sec61 complex inhibited by eeyarestatin I | | 分子名称: | N'-(4-chlorophenyl)-N-[(4R)-3-(4-chlorophenyl)-5,5-dimethyl-1-(2-{(2E)-2-[(2E)-3-(5-nitrofuran-2-yl)prop-2-en-1-ylidene]hydrazinyl}-2-oxoethyl)-2-oxoimidazolidin-4-yl]-N-hydroxyurea, Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, ... | | 著者 | Park, E, Itskanov, S. | | 登録日 | 2022-07-12 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | A common mechanism of Sec61 translocon inhibition by small molecules.
Nat.Chem.Biol., 19, 2023
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8OJ0
 | | 60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | | 登録日 | 2023-03-23 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
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8OJ8
 | | 60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native) | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | | 登録日 | 2023-03-24 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
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8DNW
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6W6L
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8B6L
 | | Subtomogram average of the human Sec61-TRAP-OSTA-translocon | | 分子名称: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, ... | | 著者 | Gemmer, M, Fedry, J.M.M, Forster, F.G. | | 登録日 | 2022-09-27 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Visualization of translation and protein biogenesis at the ER membrane.
Nature, 614, 2023
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