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PDB: 39 件
8C2F
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BU of 8c2f by Molmil
Structure of 14-3-3 sigma delta C with electrophilic peptide 3MHR-5
分子名称: 14-3-3 protein sigma, ARG-ALA-HIS-SEP-CYS-PRO-ALA-SER-LEU-GLN, CHLORIDE ION, ...
著者van den Oetelaar, M.C.M, Ottmann, C.
登録日2022-12-22
公開日2023-11-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A simple method for developing lysine targeted covalent protein reagents.
Nat Commun, 14, 2023
6HIL
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BU of 6hil by Molmil
X-ray structure of TEAD1(Y421H mutant) complexed with YAP(wildtype): Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy
分子名称: MYRISTIC ACID, Transcriptional coactivator YAP1, Transcriptional enhancer factor TEF-1
著者Kallen, J.
登録日2018-08-30
公開日2019-04-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy.
Febs J., 286, 2019
3KYS
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BU of 3kys by Molmil
Crystal structure of human YAP and TEAD complex
分子名称: 65 kDa Yes-associated protein, Transcriptional enhancer factor TEF-1
著者Li, Z, Zhao, B, Wang, P, Chen, F, Dong, Z, Yang, H, Guan, K.L, Xu, Y.
登録日2009-12-07
公開日2010-02-23
最終更新日2020-10-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into the YAP and TEAD complex
Genes Dev., 24, 2010
2LTW
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BU of 2ltw by Molmil
YAP WW1 in complex with a Smad7 derived peptide
分子名称: Smad7 derived peptide, Yorkie homolog
著者Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
登録日2012-06-04
公開日2012-11-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
1JMQ
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BU of 1jmq by Molmil
YAP65 (L30K mutant) WW domain in Complex with GTPPPPYTVG peptide
分子名称: 65 KDA YES-ASSOCIATED PROTEIN, WW Domain Binding Protein-1
著者Pires, J.R, Taha-Nejad, F, Toepert, F, Ast, T, Hoffmuller, U, Schneider-Mergener, J, Kuhne, R, Macias, M.J, Oschkinat, H.
登録日2001-07-19
公開日2001-12-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
J.Mol.Biol., 314, 2001
1K9Q
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BU of 1k9q by Molmil
YAP65 WW domain complexed to N-(n-octyl)-GPPPY-NH2
分子名称: 65 kDa Yes-associated protein, N-OCTANE, WW domain binding protein-1
著者Pires, J.R, Taha-Nejad, F, Toepert, F, Ast, T, Hoffmuller, U, Schneider-Mergener, J, Kuhne, R, Macias, M.J, Oschkinat, H.
登録日2001-10-30
公開日2001-12-28
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
J.Mol.Biol., 314, 2001
1K9R
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BU of 1k9r by Molmil
YAP65 WW domain complexed to Acetyl-PLPPY
分子名称: 65 kDa Yes-associated protein, WW domain binding protein-1
著者Pires, J.R, Taha-Nejad, F, Toepert, F, Ast, T, Hoffmuller, U, Schneider-Mergener, J, Kuhne, R, Macias, M.J, Oschkinat, H.
登録日2001-10-30
公開日2001-12-28
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
J.Mol.Biol., 314, 2001
1K5R
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BU of 1k5r by Molmil
YAP65 WW domain S24-Amino-Ethylsulfanyl-Acetic Acid mutant
分子名称: 65 KDA YES-ASSOCIATED PROTEIN, Fragment of WBP-1
著者Ferguson, N, Pires, J.R, Toepert, F, Johnson, C.M, Pan, Y.P, Volkmer-Engert, R, Schneider-Mergener, J, Daggett, V, Oschkinat, H, Fersht, A.R.
登録日2001-10-12
公開日2001-11-02
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Using flexible loop mimetics to extend phi-value analysis to secondary structure interactions.
Proc.Natl.Acad.Sci.USA, 98, 2001
5YDX
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BU of 5ydx by Molmil
NMR structure of YAP1-2 WW1 domain with LATS1 PPxY motif complex
分子名称: WW domain with PPxY motif
著者Fan, J.S, Sivaraman, J.
登録日2017-09-15
公開日2018-05-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.
Oncotarget, 9, 2018
5YDY
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BU of 5ydy by Molmil
NMR structure of YAP1-2 WW2 domain with LATS1 PPxY motif complex
分子名称: WW2 domain and PPxY motif complex
著者Fan, J.S, Sivaraman, J.
登録日2017-09-15
公開日2018-05-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.
Oncotarget, 9, 2018
2LAW
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BU of 2law by Molmil
Structure of the second WW domain from human YAP in complex with a human Smad1 derived peptide
分子名称: Mothers against decapentaplegic homolog 1, Yorkie homolog
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LAX
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BU of 2lax by Molmil
Structure of first WW domain of human YAP in complex with a human Smad1 doubly-phosphorilated derived peptide.
分子名称: Mothers against decapentaplegic homolog 1, Yorkie homolog
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LTV
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BU of 2ltv by Molmil
YAP WW2 in complex with a Smad7 derived peptide
分子名称: Smad7 derived peptide, Yorkie homolog
著者Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
登録日2012-06-04
公開日2012-11-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LAY
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BU of 2lay by Molmil
Structure of the first WW domain of human YAP in complex with a phosphorylated human Smad1 derived peptide
分子名称: Mothers against decapentaplegic homolog 1, Yorkie homolog
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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