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PDB: 19 件
2GIG
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Alteration of sequence specificity of the type II restriction endonuclease HINCII through an indirect readout mechanism
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*GP*C)-3', SODIUM ION, Type II restriction enzyme HincII
著者Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J.
登録日2006-03-28
公開日2006-07-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism.
J.Biol.Chem., 281, 2006
2GIJ
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Q138F HincII bound to cognate DNA GTTAAC and Ca2+
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*GP*C)-3', CALCIUM ION, SODIUM ION, ...
著者Horton, N.C, Joshi, H.K.
登録日2006-03-28
公開日2006-07-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism.
J.Biol.Chem., 281, 2006
3E40
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Q138F HincII bound to GTTAAC and cocrystallized with 5 mM Ca2+
分子名称: 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DP*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3'), CALCIUM ION, SODIUM ION, ...
著者Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M.
登録日2008-08-08
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献DNA distortion and specificity in a sequence-specific endonuclease.
J.Mol.Biol., 383, 2008
2AUD
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BU of 2aud by Molmil
Unliganded HincII
分子名称: Type II restriction enzyme HincII
著者Horton, N.C, Little, E.J.
登録日2005-08-27
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献DNA-induced conformational changes in Type II restriction endonucleases: The structure of unliganded HincII
J.Mol.Biol., 351, 2005
3E3Y
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BU of 3e3y by Molmil
Q138F HincII bound to GTTAAC and cocrystallized with 5 mM Ca2+
分子名称: 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DTP*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ...
著者Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M.
登録日2008-08-08
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献DNA distortion and specificity in a sequence-specific endonuclease.
J.Mol.Biol., 383, 2008
2GII
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BU of 2gii by Molmil
Q138F HincII bound to cognate DNA GTTAAC
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*GP*C)-3', Type II restriction enzyme HincII
著者Horton, N.C, Joshi, H.K.
登録日2006-03-28
公開日2006-07-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism.
J.Biol.Chem., 281, 2006
1TX3
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HINCII BOUND TO COGNATE DNA
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*G)-3', SODIUM ION, Type II restriction enzyme HindII
著者Horton, N.C, Dorner, L.F, Perona, J.J.
登録日2004-07-01
公開日2005-02-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ca2+ binding in the active site of HincII: implications for the catalytic mechanism
Biochemistry, 43, 2004
2GIH
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Q138F HincII bound to cognate DNA GTCGAC and Ca2+
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*GP*C)-3', CALCIUM ION, Type II restriction enzyme HincII
著者Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J.
登録日2006-03-28
公開日2006-07-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism.
J.Biol.Chem., 281, 2006
1XHV
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HincII bound to cleaved cognate DNA GTCGAC and Mn2+
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*C)-3', 5'-D(P*GP*AP*CP*CP*GP*G)-3', MANGANESE (II) ION, ...
著者Etzkorn, C, Horton, N.C.
登録日2004-09-20
公開日2004-09-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanistic Insights from the Structures of HincII Bound to Cognate DNA Cleaved from Addition of Mg(2+) and Mn(2+)
J.Mol.Biol., 343, 2004
3E44
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BU of 3e44 by Molmil
Q138F HincII bound to cleaved DNA (GTT | AAC) and Mn2+
分子名称: 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DT)-3', 5'-D(P*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3', MANGANESE (II) ION, ...
著者Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M.
登録日2008-08-08
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献DNA distortion and specificity in a sequence-specific endonuclease.
J.Mol.Biol., 383, 2008
3EBC
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BU of 3ebc by Molmil
Structure of N141A HincII with Cognate DNA
分子名称: 5'-D(*DGP*DCP*DCP*DCP*DGP*DTP*DCP*DGP*DAP*DCP*DCP*DGP*DGP*DC)-3', 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DCP*DGP*DAP*DCP*DGP*DGP*DGP*DC)-3', MANGANESE (II) ION, ...
著者Little, E.J, Babic, A.C, Horton, N.C.
登録日2008-08-27
公開日2008-12-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Early Interrogation and Recognition of DNA Sequence by Indirect Readout
Structure, 16, 2008
2GIE
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BU of 2gie by Molmil
HincII bound to cognate DNA GTTAAC
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*G)-3', SODIUM ION, Type II restriction enzyme HincII
著者Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J.
登録日2006-03-28
公開日2006-07-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism.
J.Biol.Chem., 281, 2006
1KC6
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BU of 1kc6 by Molmil
HincII Bound to Cognate DNA
分子名称: 5'-D(P*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*G)-3', SODIUM ION, TYPE II RESTRICTION ENZYME HINCII
著者Horton, N.C, Dorner, L.F, Perona, J.J.
登録日2001-11-07
公開日2001-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation.
Nat.Struct.Biol., 9, 2002
3E42
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BU of 3e42 by Molmil
Q138F HincII bound to GTCGAC and Ca2+ (cocrystallized)
分子名称: 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DCP*DGP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ...
著者Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M.
登録日2008-08-08
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献DNA distortion and specificity in a sequence-specific endonuclease.
J.Mol.Biol., 383, 2008
3E41
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BU of 3e41 by Molmil
Q138F HincII bound to GTCGAC and 5 mM Ca2+
分子名称: 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DCP*DGP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ...
著者Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M.
登録日2008-08-08
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献DNA distortion and specificity in a sequence-specific endonuclease.
J.Mol.Biol., 383, 2008
3E43
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BU of 3e43 by Molmil
Q138F HincII bound to GTTAAC and cocrystallized with 2.5 mM MgCl2
分子名称: 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DTP*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3', Type-2 restriction enzyme HindII, UNKNOWN ATOM OR ION
著者Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M.
登録日2008-08-08
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献DNA distortion and specificity in a sequence-specific endonuclease.
J.Mol.Biol., 383, 2008
3E45
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BU of 3e45 by Molmil
Q138F HincII bound to Noncognate DNA (GTGCAC) and Ca2+
分子名称: 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DGP*DCP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ...
著者Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M.
登録日2008-08-08
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献DNA distortion and specificity in a sequence-specific endonuclease.
J.Mol.Biol., 383, 2008
1TW8
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BU of 1tw8 by Molmil
HincII bound to Ca2+ and cognate DNA GTCGAC
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*G)-3', CALCIUM ION, Hinc II endonuclease, ...
著者Etzkorn, C, Horton, N.C.
登録日2004-06-30
公開日2004-08-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Ca2+ binding in the active site of HincII: implications for the catalytic mechanism
Biochemistry, 43, 2004
1XHU
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HincII bound to cleaved, cognate DNA containing GTCGAC
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*C)-3', 5'-D(P*GP*AP*CP*CP*GP*G)-3', Type II restriction enzyme HincII
著者Etzkorn, C, Horton, N.C.
登録日2004-09-20
公開日2004-09-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Mechanistic Insights from the Structures of HincII Bound to Cognate DNA Cleaved from Addition of Mg(2+) and Mn(2+)
J.Mol.Biol., 343, 2004

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