1CV1
| T4 LYSOZYME MUTANT V111M | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME | 著者 | Gassner, N.C, Baase, W.A, Lindstrom, J.D, Lu, J, Matthews, B.W. | 登録日 | 1999-08-20 | 公開日 | 1999-11-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding. Biochemistry, 38, 1999
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2OE4
| High Pressure Psuedo Wild Type T4 Lysozyme | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2006-12-28 | 公開日 | 2007-01-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cooperative water filling of a non-polar protein cavity observed by high-pressure crystallography and simulation Proc.Natl.Acad.Sci.USA, 102, 2005
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1OVK
| T4 Lysozyme Cavity Mutant L99A/M102Q Bound with N-Allyl-Aniline | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ... | 著者 | Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K. | 登録日 | 2003-03-26 | 公開日 | 2004-04-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Testing a Flexible-receptor Docking Algorithm in a Model Binding Site J.Mol.Biol., 337, 2004
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6X19
| Non peptide agonist CHU-128, bound to Glucagon-Like peptide-1 (GLP-1) Receptor | 分子名称: | 3-{(1S)-1-[5-(2,2-dimethylmorpholin-4-yl)-2-{(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carbonyl}-1H-indol-1-yl]butyl}-1,2,4-oxadiazol-5(4H)-one, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Belousoff, M.J, Zhang, X, Danev, R. | 登録日 | 2020-05-18 | 公開日 | 2020-09-09 | 最終更新日 | 2020-11-18 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol.Cell, 80, 2020
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175L
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1CTW
| T4 LYSOZYME MUTANT I78A | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME | 著者 | Gassner, N.C, Baase, W.A, Lindstrom, J.D, Lu, J, Matthews, B.W. | 登録日 | 1999-08-20 | 公開日 | 1999-11-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding. Biochemistry, 38, 1999
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6X18
| GLP-1 peptide hormone bound to Glucagon-Like peptide-1 (GLP-1) Receptor | 分子名称: | Glucagon, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Belousoff, M.J, Zhang, X, Danev, R. | 登録日 | 2020-05-18 | 公開日 | 2020-09-09 | 最終更新日 | 2020-11-18 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol.Cell, 80, 2020
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2OE7
| High-Pressure T4 Lysozyme | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2006-12-28 | 公開日 | 2007-01-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Rigidity of a Large Cavity-containing Protein Revealed by High-pressure Crystallography. J.Mol.Biol., 367, 2007
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205L
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3C5T
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1L82
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1C6A
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2B75
| T4 Lysozyme mutant L99A at 150 MPa | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2005-10-03 | 公開日 | 2005-11-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation Proc.Natl.Acad.Sci.Usa, 102, 2005
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1OV5
| T4 Lysozyme Cavity Mutant L99a/M102Q Bound With 2-Allylphenol | 分子名称: | 2-ALLYLPHENOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | 著者 | Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K. | 登録日 | 2003-03-25 | 公開日 | 2004-04-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Testing a Flexible-receptor Docking Algorithm in a Model Binding Site J.Mol.Biol., 337, 2004
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2B72
| T4 Lysozyme mutant L99A at 100 MPa | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2005-10-03 | 公開日 | 2005-11-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2B6T
| T4 Lysozyme mutant L99A at 200 MPa | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2005-10-03 | 公開日 | 2005-11-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural rigidity of a large cavity-containing protein revealed by high-pressure crystallography. J.Mol.Biol., 367, 2007
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2B74
| T4 Lysozyme mutant L99A at 100 MPa | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2005-10-03 | 公開日 | 2005-11-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation Proc.Natl.Acad.Sci.Usa, 102, 2005
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5OTW
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216L
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1QT4
| T26Q MUTANT OF T4 LYSOZYME | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, PROTEIN (T4 LYSOZYME) | 著者 | Kuroki, R, Weaver, L.H, Matthews, B.W. | 登録日 | 1999-06-30 | 公開日 | 1999-07-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of the conversion of T4 lysozyme into a transglycosidase by reengineering the active site. Proc.Natl.Acad.Sci.USA, 96, 1999
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2Q9E
| Structure of spin-labeled T4 lysozyme mutant S44R1 | 分子名称: | 2-HYDROXYETHYL DISULFIDE, Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | 著者 | Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L. | 登録日 | 2007-06-12 | 公開日 | 2007-06-26 | 最終更新日 | 2023-08-30 | 実験手法 | EPR (2.1 Å), X-RAY DIFFRACTION | 主引用文献 | Structural determinants of nitroxide motion in spin-labeled proteins: Solvent-exposed sites in helix B of T4 lysozyme. Protein Sci., 17, 2008
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1LWK
| Multiple Methionine Substitutions are Tolerated in T4 Lysozyme and have Coupled Effects on Folding and Stability | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Lysozyme | 著者 | Gassner, N.C, Baase, W.A, Mooers, B.H.M, Busam, R.D, Weaver, L.H, Lindstrom, J.D, Quillin, M.L, Matthews, B.M. | 登録日 | 2002-05-31 | 公開日 | 2003-05-20 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability. Biophys.Chem., 100, 2003
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252L
| GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME | 著者 | Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. | 登録日 | 1997-10-28 | 公開日 | 1998-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
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1DYG
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1DYD
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