Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 19 件
1HDO
DownloadVisualize
BU of 1hdo by Molmil
Human biliverdin IX beta reductase: NADP complex
分子名称: BILIVERDIN IX BETA REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Pereira, P.J.B, Macedo-Ribeiro, S, Parraga, A, Perez-Luque, R, Cunningham, O, Darcy, K, Mantle, T.J, Coll, M.
登録日2000-11-16
公開日2001-02-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme
Nat.Struct.Biol., 8, 2001
1HE2
DownloadVisualize
BU of 1he2 by Molmil
Human biliverdin IX beta reductase: NADP/biliverdin IX alpha ternary complex
分子名称: BILIVERDIN IX BETA REDUCTASE, BILIVERDINE IX ALPHA, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Pereira, P.J.B, Macedo-Ribeiro, S, Parraga, A, Perez-Luque, R, Cunningham, O, Darcy, K, Mantle, T.J, Coll, M.
登録日2000-11-18
公開日2001-02-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme
Nat.Struct.Biol., 8, 2001
5OOH
DownloadVisualize
BU of 5ooh by Molmil
Human biliverdin IX beta reductase: NADP/Erythrosin extra bluish ternary complex
分子名称: Erythrosin, Flavin reductase (NADPH), GLYCEROL, ...
著者Manso, J.A, Pereira, P.J.B.
登録日2017-08-07
公開日2018-03-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献In silicoand crystallographic studies identify key structural features of biliverdin IX beta reductase inhibitors having nanomolar potency.
J. Biol. Chem., 293, 2018
5OOG
DownloadVisualize
BU of 5oog by Molmil
Human biliverdin IX beta reductase: NADP/Phloxine B ternary complex
分子名称: Flavin reductase (NADPH), GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Manso, J.A, Pereira, P.J.B.
登録日2017-08-07
公開日2018-03-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献In silicoand crystallographic studies identify key structural features of biliverdin IX beta reductase inhibitors having nanomolar potency.
J. Biol. Chem., 293, 2018
7ERA
DownloadVisualize
BU of 7era by Molmil
Crystal structure of human Biliverdin IX-beta reductase B with Olsalazine Sodium (OSS)
分子名称: 5-[(E)-(3-carboxy-4-oxidanyl-phenyl)diazenyl]-2-oxidanyl-benzoic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
6OPL
DownloadVisualize
BU of 6opl by Molmil
Human biliverdin IX beta reductase Q14R mutant: NADP complex
分子名称: Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Paukovich, N.A, Eisenmesser, E.Z.
登録日2019-04-25
公開日2020-04-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Controlling biliverdin reductase B coenzyme binding through evolution
To Be Published
1HE3
DownloadVisualize
BU of 1he3 by Molmil
Human biliverdin IX beta reductase: NADP/mesobiliverdin IV alpha ternary complex
分子名称: BILIVERDIN IX BETA REDUCTASE, MESOBILIVERDIN IV ALPHA, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Pereira, P.J.B, Macedo-Ribeiro, S, Parraga, A, Perez-Luque, R, Cunningham, O, Darcy, K, Mantle, T.J, Coll, M.
登録日2000-11-18
公開日2001-02-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme
Nat.Struct.Biol., 8, 2001
1HE4
DownloadVisualize
BU of 1he4 by Molmil
Human biliverdin IX beta reductase: NADP/FMN ternary complex
分子名称: BILIVERDIN IX BETA REDUCTASE, FLAVIN MONONUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Pereira, P.J.B, Macedo-Ribeiro, S, Parraga, A, Perez-Luque, R, Cunningham, O, Darcy, K, Mantle, T.J, Coll, M.
登録日2000-11-19
公開日2001-02-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme
Nat.Struct.Biol., 8, 2001
7ER9
DownloadVisualize
BU of 7er9 by Molmil
Crystal structure of human Biliverdin IX-beta reductase B with Febuxostat (TEI)
分子名称: 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE-CARBOXYLIC ACID, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
7ER8
DownloadVisualize
BU of 7er8 by Molmil
Crystal structure of human Biliverdin IX-beta reductase B with Sulfasalazine (SAS)
分子名称: 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
1HE5
DownloadVisualize
BU of 1he5 by Molmil
Human biliverdin IX beta reductase: NADP/Lumichrome ternary complex
分子名称: BILIVERDIN IX BETA REDUCTASE, LUMICHROME, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Pereira, P.J.B, Macedo-Ribeiro, S, Parraga, A, Perez-Luque, R, Cunningham, O, Darcy, K, Mantle, T.J, Coll, M.
登録日2000-11-19
公開日2001-02-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme
Nat.Struct.Biol., 8, 2001
7ERC
DownloadVisualize
BU of 7erc by Molmil
Crystal structure of human Biliverdin IX-beta reductase B with Deferasirox (ICL)
分子名称: 4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
7ERB
DownloadVisualize
BU of 7erb by Molmil
Crystal structure of human Biliverdin IX-beta reductase B with Ataluren (PTC)
分子名称: 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
8ELL
DownloadVisualize
BU of 8ell by Molmil
Apo human biliverdin reductase beta (cryogenic)
分子名称: Flavin reductase (NADPH), SODIUM ION
著者McLeod, M.J, Eisenmesser, E.Z, Lee, E, Thorne, R.E.
登録日2022-09-26
公開日2023-09-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Identifying structural and dynamic changes during the Biliverdin Reductase B catalytic cycle.
Front Mol Biosci, 10, 2023
7ER6
DownloadVisualize
BU of 7er6 by Molmil
Crystal structure of human Biliverdin IX-beta reductase B
分子名称: Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
7ERE
DownloadVisualize
BU of 7ere by Molmil
Crystal structure of human Biliverdin IX-beta reductase B with Pyrantel Pamoate (PPA)
分子名称: 4-[(3-carboxy-2-oxidanyl-naphthalen-1-yl)methyl]-3-oxidanyl-naphthalene-2-carboxylic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
7ER7
DownloadVisualize
BU of 7er7 by Molmil
Crystal structure of hyman Biliverdin IX-beta reductase B with Tamibarotene (A80)
分子名称: 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
7ERD
DownloadVisualize
BU of 7erd by Molmil
Crystal structure of human Biliverdin IX-beta reductase B with Flunixin Meglumin (FMG)
分子名称: 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
8ELM
DownloadVisualize
BU of 8elm by Molmil
Apo human biliverdin reductase beta (293K)
分子名称: Flavin reductase (NADPH), SODIUM ION
著者McLeod, M.J, Eisenmesser, E.Z, Lee, E, Thorne, R.E.
登録日2022-09-26
公開日2023-09-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Identifying structural and dynamic changes during the Biliverdin Reductase B catalytic cycle.
Front Mol Biosci, 10, 2023

223166

件を2024-07-31に公開中

PDB statisticsPDBj update infoContact PDBjnumon